EM - Egas Moniz School of Health & Science
URI permanente desta comunidade:
A Egas Moniz School of Health & Science, entidade instituidora do Instituto Universitário Egas Moniz (anteriormente designado Instituto Superior de Ciências da Saúde Egas Moniz) e da Escola Superior de Saúde Egas Moniz (Politécnico), é uma instituição de ensino de referência dedicada à formação de profissionais de saúde, assumindo-se igualmente como um pólo de responsabilidade social fortemente inserido na comunidade local através da prestação de cuidados de saúde.
Enquanto instituição académica, desenvolve atividade pedagógica e científica, contando com um corpo docente altamente qualificado e participando em projetos de investigação científica desenvolvidos em parceria com instituições nacionais e estrangeiras.
O presente repositório visa colecionar, preservar e disponibilizar o acesso à produção científica da comunidade académica da Egas Moniz, contribuindo simultaneamente para o aumento da sua visibilidade e impacto no contexto da transferência de conhecimento.
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- 1ª consulta de Enfermagem de Saúde Infantil: estudo de casoPublication . Góias, Catarina; Loureiro, Fernanda
- 1ª Consulta de enfermagem de vigilância de saúde infantil : um estudo de casoPublication . Reis, Joana; Loureiro, Fernanda
- 2-Phenoxyethanol derivatization in ink dating determinationPublication . Leal, Teresa Argente; Ferreira, Carla; Quintas, Alexandre; Bernardo, Alexandra
- The 2018 periodontitis case definition improves accuracy performance of full-mouth partial diagnostic protocolsPublication . Botelho, João; Machado, Vanessa; Proença, Luís; Mendes, José JoãoWe aimed to compare the accuracy performance of the new 2018 periodontitis case definition by the European Federation of Periodontology (EFP)/ American Association of Periodontology (AAP) with Centers for Disease Control (CDC)/AAP 2012 in full-mouth partial recording protocols (PRP). Retrospective data from NHANES 2011-2012 and 2013-2014 were analyzed. For each case definition, full-mouth diagnostic was defined as the reference standard. Patients were diagnosed for the presence of periodontitis and staging for each PRP. Sensitivity, specificity, accuracy and precision, through several indicators, were determined. Performance measurement was assessed through binary and multiclass ROC/AUC analyses. Our performance analysis shows that the new 2018 classification outperforms the 2012 classification regarding the diagnosis and staging of periodontitis on full-mouth PRPs. This recent case definition has strengthened the utility of PRPs and its improvements certainly explain the observed findings. Also, our findings contribute to the reliability of PRPs and its use in future worldwide epidemiological surveys.
- 25 anos da descoberta à cura da Hepatite C. Análise retrospectiva de uma coorte de doentesPublication . Duarte, H.; Almeida, P.; Morais, C.; Carradinha, C.; Soares, A.; Alcobia, A.
- 3D assessment of mandibular buccal shelf geometry for optimal micro-implant placement site in Portuguese individuals : a retrospective cone-beam computed tomography studyPublication . Borga, Joana; Bugaighis, Iman; Proença, Luís; Pereira, François Durand; Costa, Helder Nunes; Pereira, Pedro MarianoObjectives: To determine the most favourable Micro-Implant (MI) insertion site along the mandibular buccal shelf (MBS), using Cone Beam Computed Tomography (CBCT). Methods: This retrospective study assessed CBCT scans from 90 Portuguese patients (32 males and 58 females, aged 14 to 40 years). Paired MBS sites were determined. Comparative and correlation analyses were performed at p < 0.05. Results: A significant increase in MBS width was observed from the mesial to the distal direction (p < 0.001). Conversely, both the MBS steepness and cortical bone thickness significantly decreased from mesial to distal (p < 0.001). Significant negative correlation was also found between age and cortical bone thickness adjacent to the distobuccal cusp and distal tangent of both mandibular second molars (r ≤ −0.373, p ≤ 0.007). Furthermore, significant asymmetric differences were identified between the right and left MBS steepness as well as in the paired cortical bone thickness at the mesiobuccal cusp, buccal groove, and distobuccal cusp of the mandibular second molar (p ≤ 0.016). Conclusions: The results indicate that although there are sufficient MBS width and cortical bone thickness, vestibular to the mandibular second molar for MI insertion, the sites towards the distal root of the mandibular second molar are more favourable when considering MBS steepness. These findings are consistent for both sexes and apply to young and old individuals.
- 3D assessment of the relationship of the mandibular buccal shelf with the mandibular canal : a CBCT retrospective studyPublication . Feliciano, Jéssica; Pereira, Pedro Mariano; Proença, Luís; Borga, Joana; Bugaighis, ImanObjective: This study aimed to evaluate the micro-implant safest insertion site on the mandibular buccal shelf (MBS) without compromising the integrity of the mandibular canal (MC). Methods: This retrospective investigation included cone-beam computed tomography (CBCT) of 96 Portuguese patients (58 females and 38 males, average age of 25.5±10.2 years). Measurements were taken in four bilateral MBS sites buccal to the mandibular second molar; tangent to the distal surface (7D), distobuccal cusp tip (7CD), buccal groove (7S) and mesiobuccal cusp tip (7CM). The transversal MBS midpoint was also determined, and the maximum angulation from the transversal MBS midpoint was extracted relative to the true vertical plane. Subsequently, the distance from the MBS midpoint to the MC was calculated at this angulation. Descriptive and inferential statistical analyses were performed at p<0.05 Results: Significant correlations were observed among several variables and age, sex and bilateral asymmetry (p<0.05). The MBS transversal width and the distance from the MBS midpoint to the MC progressively increased in the posterior direction while the angulation decreased. Conclusion: The most appropriate micro-implant insertion location compared to the other MBS investigated sites, in the absence of impacted third molars, is adjacent to the distal surface of the second molar. This finding is consistent across all age groups, sexes, and insertion sides. However, due to the demonstrated variability, taking a CBCT scan prior to mini-implant insertion might be considered to minimize the risk of injury to the inferior alveolar nerve.
- 3D bioprinting of novel κ-carrageenan bioinks : an algae-derived polysaccharidePublication . Marques, Diana M. C.; Silva, João C.; Serro, Ana Paula; Cabral, Joaquim M. S.; Sanjuan-Alberte, Paola; Ferreira, Frederico C.Novel green materials not sourced from animals and with low environmental impact are becoming increasingly appealing for biomedical and cellular agriculture applications. Marine biomaterials are a rich source of structurally diverse compounds with various biological activities. Kappa-carrageenan (κ-c) is a potential candidate for tissue engineering applications due to its gelation properties, mechanical strength, and similar structural composition of glycosaminoglycans (GAGs), possessing several advantages when compared to other algae-based materials typically used in bioprinting such as alginate. For those reasons, this material was selected as the main polysaccharide component of the bioinks developed herein. In this work, pristine κ-carrageenan bioinks were successfully formulated for the first time and used to fabricate 3D scaffolds by bioprinting. Ink formulation and printing parameters were optimized, allowing for the manufacturing of complex 3D structures. Mechanical compression tests and dry weight determination revealed young’s modulus between 24.26 and 99.90 kPa and water contents above 97%. Biocompatibility assays, using a mouse fibroblast cell line, showed high cell viability and attachment. The bioprinted cells were spread throughout the scaffolds with cells exhibiting a typical fibroblast-like morphology similar to controls. The 3D bio-/printed structures remained stable under cell culture conditions for up to 11 days, preserving high cell viability values. Overall, we established a strategy to manufacture 3D bio-/printed scaffolds through the formulation of novel bioinks with potential applications in tissue engineering and cellular agriculture.
- 3D printing for dental applicationsPublication . Figueiredo-Pina, Célio Gabriel; Serro, Ana Paula
- 3D-Printing of paracetamol tablets by fused deposition modellingPublication . Pereira, Gabriela G.; Henriques, Ana I.; Fernandes, A.I.; Santos, Inês A.; Pinto, João F.