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Study of y-SNPs genetic markers with forensic interest and ancestry informative power in Palop’s immigrant populations in Lisboa
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Orientador(es)
Resumo(s)
Since the early 70's, the flow of immigrants from African countries to Portugal has increased. According to Portugal Contemporary Base - PORDATA -, by the end of 2013, the total number of immigrants from PALOP (Portuguese-speaking
African countries) in Portugal was about 100 000, and from those, 75 000 are part of Lisboa population.
The number of immigrants in Portugal is an unavoidable reality and the migratory phenomenon in this country and, particularly in Lisboa, can become one of the main factors for the genetic variability
The single nucleotide polymorphisms (SNP) typically involve substitution of a nucleotide in DNA sequence, resulting an exchange on the sequence. SNP in forensic genetics are mainly used in samples where DNA is degraded, since only a small target DNA region is necessary because the size of the amplified product is under 100 bp. Recent advances in the SNP markers, show us the growing interest of Forensic Genetics in their use.
Markers located on the Y chromosome have special interest and application in origin and evolution population studies. Each chromosome has the story of millions of years of evolution and Y chromosome is no exception, telling the story of a male lineage. Having diverged from the same ancestral that the Xchromosome, the Y chromosome passed from generation to generation without change, except for the occurrence of mutations. Y-SNPs are single nucleotide
polymorphisms, with ancestry and population applications, and also with forensic application.
Since there is no data for Y-SNPs markers of PALOP immigrants living in Lisboa, our aim is the characterization of those groups of individuals by typing them with a panel of Y-SNPs proposed by Rosser and collaborators in 2000, with 9 YSNPs
markers, and compare different groups of individuals/populations.
Descrição
Poster apresentado no 26th Congress of the International Society for Forensic Genetics, Krakow, August 31 - September 5, 2015
Palavras-chave
Y-SNP PALOP LISBOA FORENSIC GENETICS