Percorrer por autor "Manso, Ana Cristina"
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- Autopercepção da saúde bucal em idosos de uma população urbana em Lisboa, PortugalPublication . Carvalho, Catarina; Manso, Ana Cristina; Escova, Ana; Salvado, Francisco; Nunes, CarlaOBJETIVO: Analisar se a autopercepção de saúde bucal em contexto urbano está associada aos factores sociodemográficos que interferem na qualidade de vida da saúde bucal.
- Beauty choices : uncovering the profile of who opts for aesthetic proceduresPublication . Agrizzi, Rafaela Rocha; Peroni, Matheus Bellanda; Gonçalves-Soares, Leticia Machado; Carbone, Ana Claudia; Câmara-Souza, Mariana Barbosa; Sanchez-Ayala, Alfonso; Manso, Ana Cristina; Canales, Giancarlo De la TorreBackground: The demand for aesthetic procedures has increased, driven by advances in aesthetic therapies. Therefore, understanding the factors that influence individuals to undergo aesthetic procedures is important. This study aimed to assess the profile of patients that received or did not receive aesthetic procedures. Methods: This cross-sectional study enrolled 834 female participants aged between 18 and 65 years which were divided in two groups: yes to aesthetic procedures (YAP) and no to aesthetic procedures (NAP). Participants were instructed to fill out a form that included sociodemographic questions, a question regarding performing or not aesthetic procedures and the Portuguese validated versions of five FACE-Q scales. Data were collected electronically from October 2023 to February 2025. For group comparison for continuous variables, the Yuen test was used and Fisher's exact test for categorical variables. Multivariate logistic regression was also performed to assess the influence of variables in performing aesthetic procedures. Results: The sociodemographic data showed group differences in age, education and marital status and income (p < 0.001). Botulinum toxin type A was the most common minimally invasive procedures reported by the participants. Also, volunteers of the YAP group showed greater self-perception and concern about ageing (FACE-Q1 ageing appraisal) (p=0.001). Multivariate logistic regression analysis showed that marital and education status, income and FACE-Q1 influence the decision of performing aesthetic procedures. Conclusion: Women of higher educational level, divorce, with higher income and that present higher concerns about ageing are linked to a greater likelihood of undergoing facial aesthetic procedures.
- Botulinum toxin effects on biochemical biomarkers related to inflammation-associated head and neck chronic conditions : a systematic review of clinical researchPublication . Pereira, Inês Novo; Durão, Sara; Hassan, Haidar; Braga, Ana Cristina; Almeida, André Mariz de; Manso, Ana Cristina; Faria- Almeida, Ricardo; Canales, Giancarlo De la TorreBotulinum toxin type A (BoNT) has emerged as a potential alternative to conventional therapies to many debilitating chronic diseases characterised by inflammatory states. However, the biological rationale remains ambiguous. Our review aimed to systematically assessed which biochemical biomarkers have been reported in clinical research to evaluate BoNT analgesic and mood-lifting effects in head and neck chronic conditions related to inflammation. We searched databases and registries between inception and September 29, 2023. Of the nine included studies, there were concerns about risk of bias for six studies. The leading biomarker with five studies was the calcitonin gene-related peptide (CGRP), followed by serotonin with two studies. Oxidative stress biomarkers were only reported in one study. Several important players in inflammatory processes and different immune cell classes have been evaluated in four studies. There was only one trial measuring changes in beta Tubulin and SNAP-25, and another study evaluating cutaneous neuropeptide substance-P. After BoNT, a significant effect was reported in six studies, including decrease in plasma levels of CGRP in chronic migraine and trigeminal neuralgia; serotonin decrease when collected from human tears in refractory intractable dry eye disease and increase in peripheral blood platelets in painful cervical dystonia associated to depression and anxiety; decrease in plasma concentration of markers of oxidative damage to proteins and increase in biomarkers for antioxidant power; decrease in expression of gene sets involved in inflammatory pathways and immune cells classes in the periosteum and metalloproteinase-9 molecule in the tears. BoNT seems to affect some biomarkers present in chronic inflammatory conditions. However, the certainty evidence found was very low to moderate. This study is registered on PROSPERO (CRD42023432131).
- Botulinum toxin effects on biochemical biomarkers related to inflammation-associated head and neck chronic conditions : a systematic review of preclinical researchPublication . Pereira, Inês Novo; Canales, Giancarlo De La Torre; Durão, Sara; Shado, Rawand; Braga, Ana Cristina; Almeida, André Mariz de; Hassan, Haidar; Manso, Ana Cristina; Faria-Almeida, RicardoCurrent research reported that the number of clinical studies found for botulinum toxin (BoNT) key effects on biochemical biomarkers in head and neck chronic conditions linked to inflammation was very low. There are no systematic reviews of animal studies on this topic, and hence our review aimed to evaluate the quality of the preclinical evidence. We searched PubMed, Scopus, and Web of Science databases, and registries up to 29 January 2024. There were 22 eligible records, and data were available for 11 randomised controlled trials. There were concerns about the risk of bias and great variations of data obtained regarding chronic conditions, which included mostly trigeminal neuralgia. The leading biomarkers were proinflammatory cytokines (IL-1β, TNF-α) and synaptosomal-associated protein-25 (SNAP25), followed by neuron activation marker c-Fos and calcitonin gene-related peptide (CGRP). Overall, data found that BoNT significantly altered the under/over-expression of biomarkers evoked by the investigated disease models and had no effect when the levels of these biomarkers were not changed by the induced chronic conditions in animals. However, there were some mixed results and exceptions, and the certainty evidence found was very low to low. Although the sample sizes detected significant effect size (p < 0.05), most studies are based on male inferior animals, which may limit the recommendations for clinical trials. This study is registered on PROSPERO (CRD42023432411).
- CarieCheck : an mHealth app for caries-risk self-assessment : user-perceived usability and quality in a pilot studyPublication . Guerreiro, Eduardo; Souza, Guilherme; Mendes, José João; Manso, Ana Cristina; Botelho, JoãoBackground/Objectives: Mobile health (mHealth) technologies are increasingly used to support preventive oral care and patient self-management. CarieCheck is a Portuguese app intended to improve oral health literacy and support caries-risk self-assessment. This prospective pilot study focused on users’ perceived app quality and usability, assessed with uMARS-PT. Methods: Thirty participants from the academic community of Egas Moniz School of Health and Science used the app for 30 days and completed the uMARS-PT questionnaire. Descriptive statistics were used to calculate mean scores for Engagement, Functionality, Aesthetics, Information Quality, Subjective Quality, and Perceived Impact. Results: The overall mean uMARS-PT score was 4.22, indicating excellent perceived quality. The highest domain scores were Functionality (4.51), Aesthetics (4.45), and Information Quality (4.22). Engagement (3.71) and Subjective Quality (3.05) were moderate. Perceived Impact (3.85) reflected self-reported perception of increased awareness and motivation regarding oral health behaviors. Conclusions: CarieCheck was rated highly in usability, aesthetics, and information quality. These findings suggest that CarieCheck may be considered as a digital tool for preventive education and user-supported caries-risk self-assessment. Larger, longer-term studies in diverse populations using objective behavioral and clinical outcomes are warranted.
- Caries experience and risk indicators in a Portuguese population : a cross-sectional studyPublication . Guerreiro, Eduardo; Botelho, João; Machado, Vanessa; Proença, Luís; Mendes, José João; Manso, Ana CristinaOral health surveys are essential for assessing the dental caries experience and to influence national policies. This retrospective cross-sectional study aims to analyze dental caries experience for which dental treatment was sought in a reference university dental hospital at the Lisbon Metropolitan Area between January 2016 and March 2020. Full-mouth examination, and sociodemographic, behavior, and medical information were included. Descriptive analyses and logistic regression analysis were applied to ascertain risk indicators associated with dental caries experience. A final sample of 9349 participants (5592 females/3757 males) were included, aged 18 to 99 years old. In this population, caries experience was 91.1%, higher in female participants. Age (OR = 1.01, 95% CI [1.00–1.02], occupation (OR = 2.94, 95% CI [2.37–3.65], OR = 3.35, 95% CI [2.40–4.67], OR = 2.55, 95% CI [1.66–3.91], for employed, unemployed, and retired, respectively), overweight (OR = 1.52, 95% CI [1.18–1.96]), reporting to have never visited a dentist (OR = 0.38, 95% CI [0.23–0.64], and self-reported week teeth status (OR = 2.14, 95% CI [1.40–3.28]) were identified as risk indicators for the presence of dental caries, according to adjusted multivariable logistic analyses. These results highlight a substantial rate of dental experience in a Portuguese cohort and will pave the way for future tailored oral public health programs in Portugal.
- Caries experience before and after COVID-19 restrictions : an observational studyPublication . Guerreiro, Eduardo; Botelho, João; Machado, Vanessa; Proença, Luís; Mendes, José João; Manso, Ana CristinaBackground: The declaration of COVID-19 as a pandemic by the World Health Organization in 2020 led to the suspension of several clinical practices globally, including dentistry. This study investigates the impact of these restrictions on dental caries experience. Methods: A retrospective cross-sectional study was conducted at Egas Moniz University’s dental hospital in the Lisbon Metropolitan Area from June 2019 to June 2021. The study involved 3380 participants who were divided into two cohorts: after and before COVID-19 restrictions. Data collection included a questionnaire, full-mouth clinical examinations, and radiographs (panoramic X-rays, bitewings). Results: Before the COVID-19 restrictions, the prevalence of dental caries was 91.8%, with an average DMFT (decayed, missing, and filled teeth) index of 12.13. Post-restrictions, the prevalence decreased to 84.5%, with a DMFT index of 10.99. There was an increase in missing teeth and a decrease in decayed and filled teeth. Additionally, the frequency of toothbrushing declined among participants. Conclusions: The COVID-19 pandemic restrictions have significantly impacted dental caries experiences and oral health, highlighting a decrease in dental caries, but also a concerning reduction in oral hygiene practices. These results emphasize the importance of customized dental healthcare during public health emergencies to reduce impacts and maintain oral health.
- Comparison of the effects of oral hygiene instruction methods on oral hygiene and self-perception in older adults : a randomized controlled trialPublication . Santos, Inês Caetano; Colaço, Catarina; Canales, Giancarlo De la Torre; Proença, Luís; Polido, Mário; Mendes, José João; Canhão, Helena; Manso, Ana CristinaBackground: Age-related conditions, such as being misinformed, having limited oral health literacy, and the loss of manual dexterity, autonomy, or visual acuity, may act as barriers to oral health. The aim of this study was to evaluate the effectiveness of two different oral hygiene instruction methods on oral hygiene and the self-perception of oral health in older adults. Methods: This randomized controlled trial included participants aged 65 and older who completed a questionnaire on socio-economic factors, self-perceived oral health, and oral hygiene behaviours. Oral hygiene status was assessed using the Oral Hygiene Index—Simplified (OHI-S). Participants were randomly allocated into two different groups, according to the method of oral hygiene instruction: a “General Approach” (GA) (n = 28) and a “Personalized Technique” (PT) (n = 26). After two months, a follow-up session was conducted. Data were analysed using descriptive and inferential methodologies. Results: The GA and PT methods were effective in promoting oral hygiene behaviours, with a significant increase in the use of interdental devices, but no significant differences were found between the two methods. Self-perceived oral health did not change significantly, neither after the instruction nor between methods. Significant improvements were achieved with both methods for the OHI-S, with significant differences between the two methods for the Calculus Index, where the PT achieved better results. Conclusions: Oral hygiene education leads to improvements in the adoption of oral hygiene behaviours and clinical indicators. Furthermore, a personalized approach promoted better results in clinical indicators.
- Do sociodemographic factors influence the levels of health and oral literacy? A cross-sectional studyPublication . Veladas, Francisco Manuel Veigas; Torre Canales, Giancarlo De la; Nobre, Bryanne Brissian de Souza; Escoval, Ana; Pedro, Ana Rita; Almeida, André Mariz de; Assunção, Victor Abreu; Manso, Ana CristinaBackground: Oral health literacy has gained importance in dental literature, and its relationship with oral health status and association with health status (HL) has been reported. Then, an association between the levels of HL and OHL could be expected. This study aimed to assess the levels of HL and OHL according to sociodemographic factors and to explore a possible association between HL and OHL. Methods: The European Health Literacy Survey and Oral Health Literacy Adults Questionnaire were applied to a convenience sample from Portuguese individuals. Also, sociodemographic factors such as sex, age, schooling level of the participants and their parents, and if the participants were professionals or students of the health field were assessed. To analyze the data, the Kruskal–Wallis and Mann–Whitney U tests were used to compared sociodemographic variables and the levels of literacy in general and oral health. The Spearman correlation test assessed the correlation between the levels of HL and OHL. Results: HL results showed that 45.1% of the volunteers were considered in a “problematic level” and 10.3% in “excellent level”. However, 75% presented an adequate level of OHL. Regarding the levels of HL in each sociodemographic variable, significant higher levels of “excellent level” were found in health professionals and students when compared with participants not related to health area (p < 0.001). Comparisons between the levels of OHL in each sociodemographic variable showed, significant differences regarding sex (p < 0.05), age (p < 0.001), levels of schooling of the participants and their parents (p < 0.009 and p < 0.001) and relationship with health field. (p < 0.001). A significant positive – weak correlation was found between HL and OHL (p < 0.001). Conclusions: HL and OHL levels are associated and could be influenced by sociodemographic factors.
- Effect of a tea tree oil mouthwash on plaque-induced gingivitis when comparing to chlorhexidine: an exploratory randomised clinical trialPublication . Menat, Alfred; Rozan, Cecília; Barroso, Helena; Proença, Luís; Salema-Oom, Madalena; Botelho, João; Zhiri, Abdesselam; Manso, Ana CristinaGingivitis, the most common periodontal disease, is an inflammatory condition of the gingiva resulting from bacterial biofilm accumulation without periodontal attachment loss. Chlorhexidine (CHX) is the gold standard for chemical plaque control, yet its prolonged use is associated with undesirable side effects. Tea tree essential oil (TTO, Melaleuca alternifolia), with documented antimicrobial and anti-inflammatory properties, has emerged as a potential natural alternative. This exploratory randomized, controlled, triple-blind clinical trial evaluated the antimicrobial, cytotoxic, and clinical effects of a 1% TTO-based mouthwash compared with 0.12% CHX in 30 adults with plaque-induced gingivitis. Both mouthwashes significantly reduced plaque and gingival indices as well as bacterial counts after 15 days (p < 0.001), with no significant intergroup differences in clinical outcomes. CHX achieved a greater reduction in bacterial load, while TTO presented fewer adverse effects, limited to mild taste alteration and transient increase in salivary flow. Both formulations exhibited in vitro cytotoxicity, though clinical tolerance was high. These results suggest that, under the tested conditions, TTO formulation at 1% (v/v) exerts an antibacterial effect comparable to CHX, while displaying a dose-dependent pattern.