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  • Endoscopic vacuum therapy of a refractory esophagopleural fistula in a patient with Boerhaave syndrome, using an innovative hybrid stent
    Publication . Mendes, Ivo; Nunes, Gonçalo; Vara-Luiz, Francisco; Vaz, João; Luz, Carlos; Fonseca, Jorge; Pinto-Marques, Pedro
  • Endoscopic extraction of two giant stone bezoars using mechanical and laser lithotripsy
    Publication . Oliveira, Carla; Nunes, Gonçalo; Vara-Luiz, Francisco; Oliveira, Gabriel Paiva de; Nunes, Ana; Fonseca, Jorge
  • Comunicação emocional em saúde : apresentando a ferramenta de codificação de Verona de sequências emocionais (VR-CoDES)
    Publication . Romeiro, Fernanda Bittencourt; Castro, Elisa Kern de; Carlotto, Mary Sandra
    A comunicação clínica, com foco nas competências emocionais, é uma habilidade que requer treinamento devido à necessidade de reconhecer expressões emocionais dos pacientes e dar uma resposta adequada. O objetivo deste estudo é apresentar uma ferramenta para avaliação da comunicação emocional dos profissionais de saúde, abordando as principais definições teóri-cas sobre a temática e pesquisas baseadas em evidências que aplicaram a ferramenta Codifica-ção de Verona para Sequências Emocionais(VR-CoDES). Baseado numa pesquisa de levantamen-to bibliográfico, o estudo analisa a comunicação emocional dos profissionais de saúde e o uso dessa ferramenta, tendo em vista que a comunicação é a componente chave na alta qualidade do tratamento, com impacto na satisfação e adesão dos pacientes. O estudo discute a impor-tância do reconhecimento de pistas e preocupações emocionais de pacientes em tratamentos de saúde e destaca as lacunas e desafios sobre os treinamentos de habilidades de comunicação emocional nos contextos de saúde
  • Efficacy of a new fenbendazole treatment protocol against Capillaria spp. in northern white-breasted hedgehog (Erinaceus roumanicus)
    Publication . Alfaia, Francisco; Baptista, Catarina Jota; Lozano, João; Sós-Koroknai, Viktória; Hoitsy, Márton; Carvalho, Luís M. Madeira de; Sós, Endre
    Hedgehogs, Erinaceus spp., are commonly admitted to rescue centres in European countries. However, there are still few studies on parasitological fauna and treatment possibilities, including for E. roumanicus. This study aimed to evaluate parasitism in 34 hedgehogs directly after their admission to the Budapest Zoo and Botanical Garden Wildlife Rescue Centre, as well as the efficacy of fenbendazole treatment. The Mini-Flotac method was used to quantitatively evaluate and assess the efficacy of treatment with fenbendazole (100 mg/kg PO. BID for 7 days) in five selected individuals. Faecal samples were analysed at D0 and D14 after the beginning of the treatment. Globally, the prevalence of positive animals was 76%. Capillaria spp. were the most prevalent (68%), while coccidia showed a prevalence of 32%. Considering the range of action of this benzimidazole, the treatment provided an efficacy of 100%, eliminating all forms of Capillaria spp. Considering the high number of hedgehogs admitted to rescue centres and the potential effects of parasitism in morbidity and mortality during recovery, it is essential to improve our knowledge with regard to the parasitological fauna of these species and to attain effective treatment protocols.
  • Efficacy and safety of poly-l-lactic acid in facial aesthetics : a systematic review
    Publication . Signori, Roberta; Barbosa, Antony de Paula; Cezar-dos-Santos, Fernando; Carbone, Ana Claudia; Ventura, Silvio; Nobre, Bryanne Brissian de Souza; Neves, Maria Luiza Boechat Borges; Câmara-Souza, Mariana Barbosa; Poluha, Rodrigo Lorenzi; Canales, Giancarlo De la Torre
    The primary objective of this systematic review study was to investigate the effectiveness, durability, and adverse events of PLLA treatment for aesthetic indications. The search strategy was performed in MEDLINE (Ovid). The electronic literature search of five databases was performed, from the inception of the databases until the 12th of February 2024. This was to identify randomized clinical trials that assessed PLLA treatment in adult individuals exhibiting facial aging and/or facial lipoatrophy. Risk of bias was assessed using the Cochrane Risk-of-Bias Tool for Randomized Trials (RoB 2). Eleven RCTs out of 1467 identified citations were included. Four studies showed increased dermal thickness, significant improvement in facial lipoatrophy severity and aesthetic clinical scores, after PLLA treatment with its effects sustained for at least 25 months. Two studies demonstrated the superiority of PLLA over injectable human collagen. Also, three studies showed positive results favoring PLLA when compared with PH gel in lipoatrophy severity, transepidermal water loss, skin quality, elasticity, and patient satisfaction. All adverse events were mild-to-moderate in intensity, and the main ones worth noting were bruising, hematoma, tenderness, nodules, and edema. Five out of eleven studies were considered having high risk of bias. The evidence on the effectiveness and safety of PLLA for facial rejuvenation is of low quality; thus, the reported high effectiveness, safety, and long-lasting effects for this purpose should be further investigated.
  • Effects of multisession prefrontal cortex tDCS or taVNS on stress, perceived stress and sleep quality : a double-blind, randomized controlled study
    Publication . Reis, Laya Dalila dos; Generoso, Laura Pereira; Pereira, Gabrielly Santos; Barú, João Paulo da Silva Teixeira; Candido, Natalie Lange; Capello, Maria Gabriela Maziero; Castro, Renato Ortolani Marcondes de; Cardoso, Edvaldo José Rodrigues; Scoz, Robson Dias; Ferreira, Luciano Maia Alves; Silva, Marcelo Lourenço da; Silva, Josie Resende Torres da
    Introduction: Chronic stress is a condition characterized by prolonged stimulation, leading to mental and physical weakness. It can have detrimental effects on individuals’ mental health and cognitive function, potentially causing various health issues. This article explores the potential of non-invasive neuromodulation techniques, specifically transcranial direct current stimulation (tDCS) and transcutaneous auricular vagus nerve stimulation (taVNS), in managing chronic stress and improving sleep quality.Methods: The study conducted a randomized, double-blinded, controlled trial with participants experiencing chronic stress. In total, 100 participants were randomly assigned to one of four conditions: the anodal tDCS group (n = 50), the sham tDCS group (n = 50), the taVNS group (n = 50), or the sham taVNS group (n = 50). Within each condition, participants received five sessions of either active treatment or sham treatment, with 20 min of tDCS over the dorsolateral prefrontal cortex (2 mA) for the tDCS groups, or taVNS on the left ear (20 Hz) for the taVNS groups. At baseline, post-intervention, and 4 weeks thereafter, we evaluated stress using the Lipp’s Inventory of Stress Symptoms for Adults (LSSI), perceived stress through the Perceived Stress Scale (PSS-10), and sleep quality via the Pittsburgh Sleep Quality Index (PSQI).Results: The tDCS and taVNS interventions resulted in reduced stress levels, improved sleep quality, and enhanced perception of stress.Discussion: These findings suggest that tDCS and taVNS hold promise as effective treatments for chronic stress, offering a safe and accessible approach to improving individuals’ wellbeing and overall quality of life.
  • Effectiveness, adherence and safety of home high flow nasal cannula in chronic respiratory disease and respiratory insufficiency : a systematic review
    Publication . Jácome, Cristina; Jácome, Marta; Correia, Sara; Flores, Inês; Farinha, Patrícia; Duarte, Mónica; Winck, João Carlos; Catalan, Javier Sayas; Lobato, Salvador Díaz; Luján, Manel; Caneiras, Cátia
    Introduction: The effectiveness of home high flow nasal cannula (HFNC) for the treatment of chronic respiratory failure in patients with chronic respiratory diseases (CRDs) has not been summarized. We aimed to conduct a systematic review of the effectiveness, adherence, and safety of HFNC in the long-term treatment of patients with chronic respiratory diseases and respiratory failure. Methods: A systematic review was conducted. PubMed, Web of science, and SCOPUS were search up to August 2023. Long-term HFNC studies (≥4 weeks) reporting dyspnea; exacerbations, hospitalizations; peripheral oxygen saturation (SpO2), comfort; patient experience, health-related quality of life or partial pressure of carbon dioxide (paCO2) were included. Results: Thirteen articles (701 patients) based on 10 studies were selected: randomized control trials (n = 3), randomized crossover trials (n = 2), crossover (n = 3) and retrospective (n = 2) studies. COPD (n = 6), bronchiectasis (n = 2), COPD/bronchiectasis (n = 1) and ILD (n = 1) were the underlined CRDs. HFNC reduced exacerbations when compared to usual care/home respiratory therapies (n = 6). Quality of life outcomes were also in favor of HFNC in patients with COPD and bronchiectasis (n = 6). HFNC had significant effects on hospitalizations, paCO2, and lung function. Adherence ranged from 5.2 to 8.6 h/day (n = 5). Three studies reported no events, 3 non-serious events and 2 no differences compared with other home respiratory therapies. Conclusions: HFNC seems more effective than usual care or other home respiratory therapies in reducing exacerbations and improving quality of life in patients with COPD and bronchiectasis, while presenting good adherence and being safe. Its apparently superior effectiveness needs to be better studied in future real-world pragmatic trials.
  • Effectiveness of the motivational interviewing techniques with perpetrators of intimate partner violence : a non-randomized clinical trial
    Publication . Cunha, Olga; Almeida, Telma Catarina; Gonçalves, Rui Abrunhosa; Caridade, Sónia
    The effectiveness of perpetrators’ intervention programs (PIPs) remains controversial. Readiness and motivation for change are associated with treatment success among intimate partner violence (IPV) perpetrators. In this study, we aimed to verify whether adding Motivational Interviewing Techniques (MIT) during the intake phase of a standard PIP (SPIP) increases treatment adherence. We also sought to evaluate the effectiveness of the MIT plus SPIP concerning an SPIP alone. In this non-randomized clinical trial, 50 participants were assigned to one of the two conditions SPIP alone or MIT plus SPIP. Data were collected at baseline and the end of the intervention. Proximal outcomes (dropout, intervention dose, motivation, attitudes toward IPV, problem-solving skills) and final outcomes (IPV perpetration, risk of IPV) were assessed. The Reliable Change Index (RCI) was also computed. Results indicated that SPIP plus MIT participants concluded the curriculum in a more advanced stage of change, revealed more readiness to change, evidenced greater clinical improvements, and displayed higher reductions in attitudes toward IPV, IPV perpetration, and recidivism risk than SPIP participants. These findings point to MIT’s ability to promote readiness to change and progression into the stages of change, enhancing intervention efficacy with IPV perpetrators. (NCT05484440)
  • Editorial : wildlife health consequences from environmental pollution
    Publication . Baptista, Catarina Jota; Seixas, Fernanda; Gonzalo-Orden, José M.; Oliveira, Paula A.