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Multiple Myeloma Presenting with Distal Limb Gangrene: An Odd Case Report

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Multiple myeloma (MM) is a plasmocytic malignant proliferation of a single clone resulting in an overabundance of monoclonal immunoglobulins. MM commonly presents with bone disorders, renal failure, anaemia and hypercalcaemia. Hyperviscosity syndrome is rare, as are vaso-occlusive symptoms. The authors report a dramatic case of an 80-year-old woman admitted to the emergency department with full-blown distal gangrene. The culprit turned out to be a MM, unusually presenting with symptomatic hyperviscosity and peripheral occlusive ischaemia. This catastrophic and particularly dramatic presentation is almost unprecedented, with only a few cases reported worldwide.

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multiple myeloma (MM) dystal limb gangrene Madeira Island Portugal plasmocytic malignant proliferation symptomatic hyperviscosity peripheral occlusive ischaemia

Citation

Jacinto, Joana; Malheiro, Alexandra; Pestana, Andreia; Freitas, Tiago; Brazão, M. Luz (2014) Multiple Myeloma Presenting with Distal Limb Gangrene: An Odd Case Report.European Journal of Case Reports in Internal Medicine, 1 (1).pp. 1-5.

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European Journal of Internal Case Report

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