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Development of Nevirapine resistance in children exposed to the prevention of mother-to-child HIV-1 transmission programme in Maputo, Mozambique

dc.contributor.authorAntunes, Francisco
dc.contributor.authorZindoga, Pereira
dc.contributor.authorGomes, Perpétua
dc.contributor.authorAugusto, Orvalho
dc.contributor.authorMahumane, Isabel
dc.contributor.authorVeloso, Luís
dc.contributor.authorValadas, Emília
dc.contributor.authorCamacho, Ricardo
dc.date.accessioned2016-09-28T10:38:10Z
dc.date.available2016-09-28T10:38:10Z
dc.date.issued2015-07
dc.descriptionThis is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.pt_PT
dc.description.abstract"Background: single-dose nevirapine (sd-NVP) has been the main option for prevention of mother-to-child transmission (PMTCT) of HIV-1 in low-resource settings. However, sd-NVP can induce the selection of HIV-1 resistant mutations in mothers and infants. In Mozambique, there are limited data regarding the profile of NVP resistance associated mutations (RAM) in the context of PMTCT. Objectives: to assess the prevalence and the factors associated with NVP RAM among children born to HIV-1 infected mothers enrolled in the PMTCT programme adopted in Mozambique."pt_PT
dc.identifier.citationAntunes F, Zindoga P, Gomes P, Augusto O, Mahumane I, Veloso L, et al. (2015) Development of Nevirapine Resistance in Children Exposed to the Prevention of Mother-to-Child HIV-1 Transmission Programme in Maputo, Mozambique. PLoS ONE 10 (7): e0131994. doi:10.1371/journal.pone.0131994pt_PT
dc.identifier.doi10.1371/journal.pone.0131994pt_PT
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/10400.26/14897
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherPLoSpt_PT
dc.relation.publisherversionhttp://dx.doi.org/10.1371/journal.pone.0131994pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectSingle-dose nevirapinept_PT
dc.subjectMother-to-child transmissionpt_PT
dc.subjectHIV-1pt_PT
dc.subjectMozambiquept_PT
dc.subjectNVP resistancept_PT
dc.titleDevelopment of Nevirapine resistance in children exposed to the prevention of mother-to-child HIV-1 transmission programme in Maputo, Mozambiquept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPagee0131994pt_PT
oaire.citation.titlePLoS ONEpt_PT
oaire.citation.volume10(7)pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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