Percorrer por autor "Pereira, Gabrielly Santos"
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- Effectiveness of cold-water immersion vs. massage in reducing delayed-onset muscle soreness and enhancing recovery following CrossFit® Murph Workout : randomized trialPublication . Pereira, Gabrielly Santos; Paulino, Giovana Eduarda; Almeida, Thais Helena Martins Faria de; Siqueira, Cissa Maria Ribeiro; Silva, Josie Resende Torres da; Silva, Marcelo Lourenço da; Ferreira, Luciano Maia AlvesThe Murph workout, one of the most challenging CrossFit® workouts, demands endurance and high intensity. This WOD (Workout of the Day) includes a 1-mile run, 100 pull-ups, 200 push-ups, 300 air squats, and another 1-mile run, typically performed while wearing a weighted vest. Due to its high physical demands, athletes commonly experience Delayed Onset Muscle Soreness (DOMS), characterized by increased sensitivity, fatigue, and reduced muscle function. To minimize these effects and ensure proper recovery, it is essential to adopt strategies that restore muscle function, reduce pain, and allow athletes to return to training without an elevated risk of injury. Thus, the objective of this study was to investigate the effects of massage therapy (MAS) or cold-water immersion (CWI) as a recovery intervention for DOMS in athletes following high-intensity physical activity during the CrossFit® Murph workout. For this purpose, thirty individuals with a minimum of six months of CrossFit® experience and familiarity with all exercises used in the study were recruited. Pain assessment questionnaires, including the Brief Pain Inventory (BPI) and the A-DOM questionnaire, along with a socioeconomic questionnaire, were administered before and after WOD. Additionally, pain assessments were conducted using algometry and thermographic imaging. After completing the WOD, participants were randomly assigned to one of two recovery interventions: MAS or CWI. The study results highlight the differential impacts of CWI and MAS on pain management and recovery dynamics following structured exercise. Our findings clearly demonstrate that CWI significantly reduces pain prevalence, both at rest and during exercise, as evidenced by the absence of pain reports from participants 48 hours after the intervention. While our study provides valuable insights into the effectiveness of CWI and MAS for post-exercise recovery, limitations such as the non-blinded study design and small sample size may influence the generalizability of the findings.
- The effectiveness of spinal cord stimulation combined with physiotherapy in the management of chronic pain in adults : a systematic reviewPublication . Barros, Adilia Maria Soares Porciuncula; Pereira, Gabrielly Santos; Silva, Josie Resende Torres da; Silva, Marcelo Lourenço da; Silva, Maria do Desterro da Costa e; Ferreira, Luciano Maia AlvesBackground: Chronic pain affects a significant portion of the population, and conventional treatments often prove insufficient. Spinal Cord Stimulation (SCS), a neuromodulation technique, has shown benefits in pain relief, while physiotherapy is widely employed to enhance physical function and quality of life. Although the combination of these approaches may offer synergistic effects, existing evidence is limited and fragmented. Objective: This systematic review aimed to evaluate the clinical outcomes of Spinal Cord Stimulation (SCS), with or without the association of physiotherapy, in the management of chronic pain in adults. Methodology: The review was conducted following PRISMA guidelines and the PICO strategy. A comprehensive search was performed across databases including Cochrane Library, ScienceDirect, BASE, and VHL (BVS: MEDLINE, IBECS, WPRIM, LILACS, PERIÓDICO CAPES) using MeSH terms and Boolean operators: (“Spinal Cord Stimulation” OR “Neuromodulation”) AND (“Chronic Pain” OR “Pain Management”) AND (“Physical Therapy Modalities” OR “Physiotherapy” OR “Rehabilitation”). Only studies published in English, Spanish, or Portuguese in the past 10 years were included, focusing on chronic pain and reporting outcomes related to pain reduction and functional improvement. Results: Eight studies comprising 777 patients were included. Spinal cord stimulation alone led to significant pain reductions, with responder rates above 80% and average decreases of 5–6 cm on pain scales. Improvements in quality of life and functional disability were also reported, with reductions of over 30 points in disability indices and up to 40% in opioid use. However, only one study included physiotherapy as a complementary intervention, without isolating its effects. No study directly evaluated the combined efficacy of SCS and physiotherapy, highlighting a gap in the literature. Conclusion: The findings highlight the proven effectiveness of SCS in chronic pain management but reveal a lack of studies assessing its integration with physiotherapy. Future clinical trials should address this gap to explore potential synergistic effects and optimize interdisciplinary pain treatment strategies.
- Effects of multisession prefrontal cortex tDCS or taVNS on stress, perceived stress and sleep quality : a double-blind, randomized controlled studyPublication . Reis, Laya Dalila dos; Generoso, Laura Pereira; Pereira, Gabrielly Santos; Barú, João Paulo da Silva Teixeira; Candido, Natalie Lange; Capello, Maria Gabriela Maziero; Castro, Renato Ortolani Marcondes de; Cardoso, Edvaldo José Rodrigues; Scoz, Robson Dias; Ferreira, Luciano Maia Alves; Silva, Marcelo Lourenço da; Silva, Josie Resende Torres daIntroduction: Chronic stress is a condition characterized by prolonged stimulation, leading to mental and physical weakness. It can have detrimental effects on individuals’ mental health and cognitive function, potentially causing various health issues. This article explores the potential of non-invasive neuromodulation techniques, specifically transcranial direct current stimulation (tDCS) and transcutaneous auricular vagus nerve stimulation (taVNS), in managing chronic stress and improving sleep quality.Methods: The study conducted a randomized, double-blinded, controlled trial with participants experiencing chronic stress. In total, 100 participants were randomly assigned to one of four conditions: the anodal tDCS group (n = 50), the sham tDCS group (n = 50), the taVNS group (n = 50), or the sham taVNS group (n = 50). Within each condition, participants received five sessions of either active treatment or sham treatment, with 20 min of tDCS over the dorsolateral prefrontal cortex (2 mA) for the tDCS groups, or taVNS on the left ear (20 Hz) for the taVNS groups. At baseline, post-intervention, and 4 weeks thereafter, we evaluated stress using the Lipp’s Inventory of Stress Symptoms for Adults (LSSI), perceived stress through the Perceived Stress Scale (PSS-10), and sleep quality via the Pittsburgh Sleep Quality Index (PSQI).Results: The tDCS and taVNS interventions resulted in reduced stress levels, improved sleep quality, and enhanced perception of stress.Discussion: These findings suggest that tDCS and taVNS hold promise as effective treatments for chronic stress, offering a safe and accessible approach to improving individuals’ wellbeing and overall quality of life.
- Non-invasive neuromodulation for pain management in children and adolescents : a systematic review of randomized controlled trialsPublication . Pereira, Gabrielly Santos; Silva, Marcelo Lourenço da; Oliveira, Ana Beatriz; Ferreira, Luciano Maia AlvesPain in children and adolescents remains an underestimated and undertreated condition, with long-term physical and psychosocial consequences. Non-invasive neuromodulation has emerged as a promising, low-risk approach for managing acute and chronic pain by modulating central and peripheral neural pathways. This systematic review followed PRISMA 2020 guidelines to evaluate the efficacy, safety, and clinical applicability of non-invasive neuromodulation techniques in pediatric pain. Searches were conducted in PubMed, Embase, Scopus, Web of Science, Cochrane CENTRAL, and ScienceDirect for randomized controlled trials (RCTs) published between 2015 and 2025. Six RCTs met the inclusion criteria, encompassing percutaneous electrical nerve field stimulation (PENFS), transcutaneous auricular vagus nerve stimulation (taVNS), transcutaneous electrical acupoint stimulation (TEAS), and transcutaneous electrical nerve stimulation (TENS). Four trials reported significant reductions in pain intensity alongside improvements in functional outcomes and quality of life, particularly in functional abdominal pain and postoperative contexts. Most studies showed low or moderate risk across domains, with appropriate randomization and blinded assessment. No serious adverse events were reported, confirming an excellent safety profile. These findings support non-invasive neuromodulation as a feasible and well-tolerated adjunct to conventional pediatric pain management. Further high-quality trials are warranted to standardize protocols and explore mechanisms of neuroplasticity in the developing nervous system. PROSPERO (CRD420251170866).
- Photobiomodulation in chronic pain : a systematic review of randomized clinical trialsPublication . Ferreira, Luciano Maia Alves; Oliveira, Ana Beatriz Cabral; Mendes, José João; Costa, Gabrielle Vitoria; Silva, Izadora Reis; Santos, Gabrielly Nogueira; Pereira, Gabrielly Santos; Silva, Marcelo LourençoIntroduction: Photobiomodulation (PBM) stands out as a promising therapeutic alternative for the management of chronic pain, but there is still controversy regarding its efficacy and safety, given the diversity of protocols and populations evaluated. Objectives: To critically review the available literature on the use of PBM in adults with chronic pain conditions, synthesizing the evidence on analgesic and functional effects, impact on quality of life, and safety profile. Methods: A systematic search was conducted in PubMed, Embase, Scopus, LILACS, and MEDLINE, including articles published between September 2015 and September 2025. Randomized clinical trials that compared PBM protocols to placebo, sham, or conventional care were selected. The outcomes investigated included pain intensity (primary), function, quality of life, and occurrence of adverse events (secondary). Results: Fourteen studies were included, covering populations with fibromyalgia, peripheral neuropathies, orofacial pain, and musculoskeletal pain. Most trials demonstrated significant pain reduction with PBM, particularly in fibromyalgia and neuropathy. In some studies, functional gains and improved quality of life were observed. The incidence of adverse events was low, reinforcing the method’s safety, although the heterogeneity of technical parameters compromises the standardization of results. Conclusion: PBM has analgesic potential and a safe profile for managing chronic pain, especially in cases difficult to control with conventional therapies. However, the variability of clinical parameters and limited follow-up still hinder more comprehensive recommendations. Additional multicenter studies with standardized protocols are needed to consolidate clinical guidelines.
- Transcutaneous auricular vagus nerve stimulation modulates masseter muscle activity, pain perception, and anxiety levels in university students : a double-blind, randomized, controlled clinical trialPublication . Ferreira, Luciano Maia Alves; Brites, Ricardo; Fraião, Gonçalo; Pereira, Gonçalo Pereira; Fernandes, Henrique; Brito, José Américo Almeida de; Generoso, Laura Pereira; Capello, Maria Gabriela Maziero; Pereira, Gabrielly Santos; Scoz, Robson Dias; Silva, Josie Resende Torres; Silva, Marcelo LourençoIntroduction: Chronic anxiety is a statemarked by sustained activation of the masseter muscle, manifesting in both mental and physical strain. This prolonged tension can significantly impact mental wellbeing and cognitive abilities, posing a risk for a range of health complications. This double-blind, randomized, controlled clinical trial investigated the impact of transcutaneous auricular vagus nerve stimulation (TAVNS) on masseter muscle activity, pressure pain threshold (PPT), and anxiety levels in university students with elevated anxiety. Methods: Forty-two participants meeting inclusion criteria were randomly assigned to either active TAVNS or sham TAVNS groups. Various parameters, including masseter muscle electromyographic (EMG) signals, PPT, and Beck Anxiety Inventory (BAI) scores, were assessed before pretreatment, immediately after the intervention week, and 2 weeks follow-up. Results: Active TAVNS significantly reduced both left and right masseter activation during resting mandibular position, persisting for 2 weeks post-intervention. Additionally, TAVNS induced a lasting decrease in both left and right masseter PPT, indicative of altered pain perception. Notably, BAI scores showed a substantial reduction, emphasizing TAVNS as a potential intervention for anxiety, with effects maintained at the 2-week follow-up. Discussion: This study provides comprehensive insights into the multifaceted effects of TAVNS on physiological and psychological aspects associated with anxiety in university students. The promising results underscore TAVNS as a potential neuromodulatory intervention for anxiety-related conditions, warranting further research and clinical exploration.