Percorrer por autor "Costa, Cristina"
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- Clinical rating scale for pantothenate kinase-associated neurodegeneration: A pilot studyPublication . Darling, Alejandra; Tello, Cristina; Martí, María Josep; Garrido, Cristina; Aguilera-Albesa, Sergio; Tomás Vila, Miguel; Gastón, Itziar; Madruga, Marcos; González Gutiérrez, Luis; Ramos Lizana, Julio; Pujol, Montserrat; Gavilán Iglesias, Tania; Tustin, Kylee; Lin, Jean Pierre; Zorzi, Giovanna; Nardocci, Nardo; Martorell, Loreto; Lorenzo Sanz, Gustavo; Gutiérrez, Fuencisla; García, Pedro J.; Vela, Lidia; Hernández Lahoz, Carlos; Ortigoza Escobar, Juan Darío; Martí Sánchez, Laura; Moreira, Fradique; Coelho, Miguel; Correia Guedes, Leonor; Castro Caldas, Ana; Ferreira, Joaquim; Pires, Paula; Costa, Cristina; Rego, Paulo; Magalhães, Marina; Stamelou, María; Cuadras Pallejà, Daniel; Rodríguez-Blazquez, Carmen; Martínez-Martín, Pablo; Lupo, Vincenzo; Stefanis, Leonidas; Pons, Roser; Espinós, Carmen; Temudo, Teresa; Pérez Dueñas, BelénPantothenate kinase-associated neurodegeneration is a progressive neurological disorder occurring in both childhood and adulthood. The objective of this study was to design and pilot-test a disease-specific clinical rating scale for the assessment of patients with pantothenate kinase-associated neurodegeneration.
- Expert perspectives on the use of safinamide for Parkinson’s disease in Portugal : insights from a Portuguese Delphi ConsensusPublication . Rodrigues, Ana Margarida; Costa, Cristina; Gago, Miguel; Grunho, Miguel; Guedes, Leonor Correia; Morgadinho, Ana; Rosas, Maria José; Simões, Rita; Velon, Ana GraçaAim: Safinamide is an approved medication for managing motor fluctuations in Parkinson’s disease (PD). However, limited data exist regarding its application in clinical practice in Portugal and the perspectives of Portuguese neurologists on its use. To address this, a group of Portuguese specialists with recognized expertise in PD management convened to compile the insights on various aspects of safinamide use in PD patients among the field and to develop recommendations aimed at informing and guiding physicians in Portugal on its optimal clinical application. Materials & methods: A focus group composed of nine Portuguese PD experts developed a questionnaire building on the 2022 European Delphi study, and employed a Delphi methodology approach to gather the views of Portuguese neurologists with a minimum of 5 years of clinical experience with safinamide (n = 35). A final online questionnaire comprising 35 statements was administered in a single-round Delphi format, utilizing a 5-point Likert scale. Consensus was defined as achieving ≥66% agreement or disagreement among the panelists. Results: A strong consensus emerged among Portuguese neurologists regarding the therapeutic efficacy of safinamide in addressing motor symptoms, motor fluctuations and quality of life. Additionally, agreement was reached on its positive effects on nonmotor symptoms such as sleep, fatigue, mood, quality of life and pain management. However, no consensus was achieved regarding safinamide’s efficacy in managing orthostatic hypotension, cognitive issues, urinary and sexual dysfunction, as well as its safety profile in PD patients with hallucinations. Overall, the opinions of Portuguese neurologists aligned closely with those of their European counterparts. Conclusion: This Delphi study highlights the consensus among Portuguese neurologists on the efficacy of safinamide for managing motor symptoms in PD. The considerations presented herein offer essential guidance for effectively managing PD with safinamide, ultimately enhancing patient care in Portugal.
- Exploring the Application of a Co-Creation Model in Archaeological Tourism: Two Case Studies developed under TURARQ's project within the frame of Link Me Up - 1000 ideas projectPublication . Garcês, Sara; Gomes, Hugo; Martins, Marco; Trindade, Anícia; Costa, Cristina; Manso, António Manuel Rodrigues; Marques, C. G.
- Trabalho Livre nº 18 - Síndrome de FournierPublication . Reia, Marta; Costa, Cristina; Mourato, Beatriz; Taré, Filipa; Fialho, GuilhermeO Síndrome de Fournier, também conhecido como fasceíte necrotizante do períneo, é uma infeção rara mas grave e que resulta muitas vezes da manipulação urológica ou proctológica, sendo mais frequente em doentes imunodeprimidos ou com Diabetes Mellitus. Caracteriza-se por uma infeção aguda dos tecidos moles e fáscias do períneo com celulite necrotizante secundária a bactérias gram-negativas e anaeróbias.