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Browsing by Author "Barros, Andreia"

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  • Dengue em Portugal – Experiência da Região Autónoma da madeira
    Publication . Castro, Leonor; Marçal, Filipa; Goncalves, Jenny F; Oliveira, Joana; Miranda, Victor; Freitas, Cristina; Barros, Andreia; Freitas, Pedro
    Introduction: Dengue is a self-limited viral disease, transmitted by infected Aedes mosquitoes. The introduction of the vector to the island of Madeira raised the menace of an epidemic outbreak. Despite the implementation of vector control measures, the first dengue outbreak was reported eight years after the first detection of the vector in the region. The objective of this study was to characterize cases in paediatric ages during the first outbreak of dengue in Madeira. Methods: We performed a retrospective, observational, descriptive study including children aged 0 to 14 years with laboratory confirmed dengue. Clinical, demographic and laboratory variables were characterized, followed by statistical analysis.Results: One hundred and eighty-two cases were confirmed by laboratory methods, predominantly male, mean age 9.6 years. The incidence was 413.5/100 000 population, the peak incidence being observed in November 2012. The most frequently described symptoms were fever (98.3%), headache (75.2%), myalgia (66.5%) and rash (51.6%). Bleeding was identified in 9.9% of cases. Of the paediatric cases,15.9% were admitted, with a mean duration of 3.8 days. No deaths were reported. Only the DEN-1 serotype was identified. Conclusions: The high density of the vector, together with susceptible hosts, may have triggered the outbreak following the introduction of the virus in the region. Given the possibility of a new outbreak, and since immunity is specific to the infecting serotype, vector management strategies and individual protection measures must be sustained.
    2014Journal article Open access Show more
  • Diffuse infantile hepatic haemangioma—how to manage an incidental but potentially lethal finding
    Publication . Rodrigues, Alexandra; Forno, Andreia; Costa, Edite; Berenguer, Alberto; Pilar, Carla; Loureiro, Rui; Rufino, Duarte; Barros, Andreia; Teixeira, Filomena
    Infantile hepatic haemangioma (IHH) is a rare vascular tumour that is potentially lethal due to its associated complications, including heart failure, hepatic failure, hypothyroidism and abdominal compartment syndrome. The authors report a case of an asymptomatic diffuse IHH in a newborn male, which was presented as an incidental finding at the time that the patient was diagnosed with pyloric stenosis. The patient was treated with increasing doses of propranolol that were well tolerated. With the regression of the IHH by the time that the patient reached one year of age, there was a significant imagiologic improvement. Because there is no consensus on the optimal approach for the treatment of liver tumours in newborns, it is important to adopt a systematic approach. After the diagnosis of diffuse IHH has been established, the decision to initiate treatment and the therapeutic of choice is often controversial. Regular follow-up is recommended to monitor possible complications.
    2018Journal article Open access Show more