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IANA - Comunicações em Eventos Científicos

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http://hdl.handle.net/10400.26/7948

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Browsing IANA - Comunicações em Eventos Científicos by Author "Cunha, Teresa Margarida"

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  • Assessing of depth of myometrial invasion and preoperative staging of endometrial cancer: the added value of diffusion-weighted imaging and dynamic contrast-enhanced MRI sequences
    Publication . Alves, Inês; Ramalho, Madalena; Cunha, Teresa Margarida
    Purpose: To compare T2-weighted image (T2WI) vs dynamic contrastenhanced magnetic resonance imaging (DCE-MRI) vs diffusion-weighted imaging (DWI) for the evaluation of depth of myometrial invasion and preoperative overall staging of endometrial cancer. Methods and Materials: This retrospective study included forty-four women with endometrial cancer who underwent 1.5 Tesla pelvic MRI as part of their initial preoperative staging. T2WI, DCE-MRI, and DWI sequences were obtained. Retrospectively, two radiologists performed a consensus interpretation of all images interpreted the depth of myometrial invasion, overall stage, and presence of pitfalls. Surgical histology was available for each case and was the gold standard for comparison. The accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for each method were assessed. Results: Respective diagnostic accuracy, sensitivity, specificity, PPV and NPV in assessing the depth of myometrial invasion were: T2WI 61%, 58%, 64%, 55% and 67%; DCE-MRI 86%, 84%, 88%, 84% and 88%; DWI 95%, 95%, 96%, 95% and 96%. DWI correctly staged more patients (41/44) than DCEMRI (34/44) and T2WI (22/44) (P<0.05). For overall cancer staging, κ values were 0.29 with T2WI, 0.59 with DCE-MRI, and 0.89 with DWI. Conclusion: DWI considerably improved the diagnostic sensitivity and accuracy of MRI compared to DCE-MRI and T2WI in assessing both depth of myometrial invasion and overall staging in endometrial cancer.
    2017Book part Open access Show more
  • Mistakes in assessment of endometrial cancer
    Publication . Cunha, Teresa Margarida; Horta, Mariana
    Pelvic MR imaging allows to avoid most of the mistakes in the assessment of ovarian masses made using transvaginal ultrasonography or CT scan. However, even using pelvic MR imaging, there are some pathologies that may mimic primitive ovarian cancer including pelvic inflammatory disease, uterine myoma, digestive tumour or ovarian metastases. Preoperative diagnosis of these pathologies is crucial because the therapeutic strategy is completely different and the absence of a diagnosis may impact the prognosis. Thus, this lecture will present three clinical situations where the radiologist needs to accurately analyse MR images to not misdiagnose a wide variety of pelvic pathologies as ovarian cancer. Learning Objectives: 1. To become familiar with benign masses mimicking ovarian cancer. 2. To demonstrate benign and malignant diseases mimicking peritoneal carcinomatosis. 3. To learn about imaging strategies for avoiding these pitfalls.
    2017Book part Open access Show more