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Enterite Linfoplasmocítica em equinos: Estudo de um caso clínico
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Advisor(s)
Abstract(s)
A enterite linfoplasmocítica é uma causa pouco frequente da doença inflamatória intestinal, em equinos. A inflamação da mucosa ocorre através de uma infiltração por células inflamatórias prejudicando os processos de absorção e digestão, resultando na perda crónica de peso, dor abdominal recorrente e hipoproteinémia.
Esta dissertação de mestrado aborda um caso clínico de um equino de 25 anos de idade com enterite linfoplasmocitíca que originou caquexia severa e episódios recorrentes de cólica, com duração superior a um ano.
Foram realizados exames complementares de diagnóstico, incluído ecografia abdominal e retal, abdominocentese e análise sanguínea, dentro das possibilidades económicas e expectativas do proprietário. São ainda abordados quais os exames complementares de diagnóstico que se deveriam ter realizado para um diagnóstico definitivo.
Inicialmente e num curto espaço de tempo, observou-se uma resposta positiva ao tratamento farmacológico e à dieta fornecida ao animal. Contudo o reaparecimento de cólica recorrente determinou a eutanásia do animal.
Durante a necropsia observou-se que 80% do intestino delgado estava espessado, tendo-se retirado uma amostra e enviado para análise histopatológica que revelou um diagnóstico de enterite linfoplasmocítica.
Lymphoplasmocytic enteritis is not a common cause for inflammatory bowel disease in equines. The inflammation of the mucosa occurs due to an infiltration of inflammatory cells that alter the absorption and digestion processes, resulting in chronic weight loss, recurrent abdominal pain and hypoproteinemia. This dissertation approaches a clinical case of a 25 year old equine with lymphoplasmocytic enteritis that lead to severe cachexia and recurrent colic episodes, with over a year duration. Diagnostic complementary exams were executed, including abdominal and rectal ultrasound, abdominocentesis and blood tests, within the economic possibilities and expectations of the owner. The dissertation also approaches the diagnostic complementary exams that should have been executed for a more precise diagnose. Initially and in a short space of time, a positive response to pharmacologic treatment and change of diet was observed. The reappearance of recurrent colic lead to euthanasia. During observation in the necropsy 80% of the small intestine has thickened walls, a sample was collected and sent to histopathologic analysis that revealed the lymphoplasmocytic enteritis diagnosis.
Lymphoplasmocytic enteritis is not a common cause for inflammatory bowel disease in equines. The inflammation of the mucosa occurs due to an infiltration of inflammatory cells that alter the absorption and digestion processes, resulting in chronic weight loss, recurrent abdominal pain and hypoproteinemia. This dissertation approaches a clinical case of a 25 year old equine with lymphoplasmocytic enteritis that lead to severe cachexia and recurrent colic episodes, with over a year duration. Diagnostic complementary exams were executed, including abdominal and rectal ultrasound, abdominocentesis and blood tests, within the economic possibilities and expectations of the owner. The dissertation also approaches the diagnostic complementary exams that should have been executed for a more precise diagnose. Initially and in a short space of time, a positive response to pharmacologic treatment and change of diet was observed. The reappearance of recurrent colic lead to euthanasia. During observation in the necropsy 80% of the small intestine has thickened walls, a sample was collected and sent to histopathologic analysis that revealed the lymphoplasmocytic enteritis diagnosis.
Description
Keywords
Enterite linfoplasmocítica Doença inflamatória intestinal Perda de peso crónica Cólica Equino Lymphoplasmocytic enteritis Inflammatory bowel disease Chronic weight loss Colic Equine