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Publication
Carcinoma pavimento-celular da língua
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Advisor(s)
Abstract(s)
O carcinoma pavimento-celular da língua, tal como outras formas de cancro oral e da orofaringe, é uma doença de elevada complexidade, difícil de tratar, mas cuja etiologia está na maior parte dos casos associada a hábitos culturais. Por outro lado, uma vez desenvolvida a doença, verifica-se que o seu tratamento pode ser simplificado se diagnosticada precocemente. A existência deste trabalho no âmbito da medicina dentária
deve-se apesar de tudo à importância do médico dentista na fase maior probabilidade de sucesso no combate à doença: prevenção e diagnóstico precoce. Por forma a contribuir para a consciencialização acerca da doença, foi feita uma revisão geral, descrevendo-se os principais aspetos da doença: na epidemiologia onde se verifica uma dispersão que acompanha a dos principais fatores etiológicos ; na carcinogénese, com a noção da acumulação de alterações genéticas com vista a progénie mutante e sua heterogeneidade;
nos fatores etiológicos com o destaque para o efeito sinérgico tabaco-álcool e infeção por vírus como o HPV, entre outros; na prevenção, com destaque para o Projeto de Intervenção Precoce no Cancro Oral – PIPCO ; na anatomia , pela importante perceção de como a localização topográfica e restantes características anatómicas ajudam a explicar a dispersão da doença ; na patogénese pela explicação do cursar da doença; na identificação de lesões potencialmente malignas, apresentação clinica da doença, caracterização de sinais e sintomas e descrição dos principais exames complementares de diagnostico, pela sua importância com vista ao diagnostico; no prognostico e consequentes grupos de estadiamento identificando os principais fatores e já atualizando os respetivos grupos de estadiamento; no tratamento, fazendo referência a algumas das
abordagens mais utilizadas e últimas técnicas, nomeadamente no âmbito da cirurgia robótica ; na descrição das principais complicações e sequelas ao tratamento sua gestão e análise da resultante qualidade de vida.
Squamous cell carcinoma of the tongue, like other forms of oral and oropharyngeal cancer, is a highly complex disease, difficult to treat, but whose etiology is in most cases associated with cultural habits. On the other hand, once the disease develops, it appears that its treatment can be simplified if diagnosed early. The existence of this work in the field of dentistry is, despite everything, due to the importance of the dental surgeon in the phase that is most likely to be successful in combating the disease: prevention and early diagnosis. In order to contribute to raising awareness about the disease, a general review was carried out, describing the main aspects of the disease: in epidemiology, where there is a dispersion that accompanies the main etiological factors; in carcinogenesis, with the notion of the accumulation of genetic changes aimed at mutant progeny and their heterogeneity; in etiological factors, with emphasis on the synergistic effect of tobaccoalcohol and infection by viruses such as HPV, among others; in prevention, with an emphasis on the Early Oral Cancer Intervention Project – PIPCO; in anatomy, due to the important perception of how topographic location and other anatomical characteristics help to explain the spread of the disease; in pathogenesis by explaining the course of the disease; in the identification of potentially malignant lesions, clinical presentation of the disease, characterization of signs and symptoms and description of the main complementary diagnostic tests, due to their importance for diagnosis; in the prognosis and consequent staging groups, identifying the main factors and updating the respective staging groups; in treatment, making reference to some of the most used approaches and latest techniques, particularly within the scope of robotic surgery; in the description of the main complications and sequelae of treatment, management and analysis of the resulting quality of life.
Squamous cell carcinoma of the tongue, like other forms of oral and oropharyngeal cancer, is a highly complex disease, difficult to treat, but whose etiology is in most cases associated with cultural habits. On the other hand, once the disease develops, it appears that its treatment can be simplified if diagnosed early. The existence of this work in the field of dentistry is, despite everything, due to the importance of the dental surgeon in the phase that is most likely to be successful in combating the disease: prevention and early diagnosis. In order to contribute to raising awareness about the disease, a general review was carried out, describing the main aspects of the disease: in epidemiology, where there is a dispersion that accompanies the main etiological factors; in carcinogenesis, with the notion of the accumulation of genetic changes aimed at mutant progeny and their heterogeneity; in etiological factors, with emphasis on the synergistic effect of tobaccoalcohol and infection by viruses such as HPV, among others; in prevention, with an emphasis on the Early Oral Cancer Intervention Project – PIPCO; in anatomy, due to the important perception of how topographic location and other anatomical characteristics help to explain the spread of the disease; in pathogenesis by explaining the course of the disease; in the identification of potentially malignant lesions, clinical presentation of the disease, characterization of signs and symptoms and description of the main complementary diagnostic tests, due to their importance for diagnosis; in the prognosis and consequent staging groups, identifying the main factors and updating the respective staging groups; in treatment, making reference to some of the most used approaches and latest techniques, particularly within the scope of robotic surgery; in the description of the main complications and sequelae of treatment, management and analysis of the resulting quality of life.
Description
Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas Moniz
Keywords
Cancro oral Carcinoma pavimento-celular língua Cancro oral rastreio dentista Cancro cabeça e pescoço