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Brain Activity during Lower-Limb Movement with Manual Facilitation: An fMRI Study

dc.contributor.authorAlmeida, Patrícia
dc.contributor.authorVieira, Ana Isabel
dc.contributor.authorCanário, Nádia
dc.contributor.authorCastelo-Branco, Miguel
dc.contributor.authorCastro-Caldas, Alexandre
dc.date.accessioned2022-03-22T11:49:10Z
dc.date.available2022-03-22T11:49:10Z
dc.date.issued2014-12-17
dc.description.abstractBrain activity knowledge of healthy subjects is an important reference in the context of motor control and reeducation. While the normal brain behavior for upper-limb motor control has been widely explored, the same is not true for lower-limb control. Also the effects that different stimuli can evoke on movement and respective brain activity are important in the context of motor potentialization and reeducation. For a better understanding of these processes, a functional magnetic resonance imaging (fMRI) was used to collect data of 10 healthy subjects performing lower-limb multijoint functional movement under three stimuli: verbal stimulus, manual facilitation, and verbal +manual facilitation. Results showed that, with verbal stimulus, both lower limbs elicit bilateral cortical brain activation; with manual facilitation, only the left lower limb (LLL) elicits bilateral activation while the right lower limb (RLL) elicits contralateral activation; verbal + manual facilitation elicits bilateral activation for the LLL and contralateral activation for the RLL. Manual facilitation also elicits subcortical activation in white matter, the thalamus, pons, and cerebellum. Deactivations were also found for lower-limb movement. Manual facilitation is stimulus capable of generating brain activity in healthy subjects. Stimuli need to be specific for bilateral activation and regarding which brain areas we aim to activate.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doihttp://dx.doi.org/10.1155/2015/701452pt_PT
dc.identifier.issn2090-1860
dc.identifier.urihttp://hdl.handle.net/10400.26/39783
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherHindawi Publishing Corporationpt_PT
dc.subjectBrain activitypt_PT
dc.subjectLower limb movementpt_PT
dc.subjectMotor controlpt_PT
dc.subjectReeducationpt_PT
dc.titleBrain Activity during Lower-Limb Movement with Manual Facilitation: An fMRI Studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage15pt_PT
oaire.citation.startPage1pt_PT
oaire.citation.titleNeurology Research Internationalpt_PT
oaire.citation.volume2015pt_PT
person.familyNameAlmeida
person.familyNameVieira
person.givenNamePatrícia
person.givenNameAna Isabel
person.identifier.ciencia-id651F-7E53-A25D
person.identifier.orcid0000-0003-2081-3976
person.identifier.orcid0000-0001-6023-2362
person.identifier.scopus-author-id56537784900
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationbc4b6a8c-d8e9-4abb-bd31-0649133227c0
relation.isAuthorOfPublication712b9d4f-f724-4d4b-a82d-c8784ee32ace
relation.isAuthorOfPublication.latestForDiscoverybc4b6a8c-d8e9-4abb-bd31-0649133227c0

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