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Eficácia de um estimulante salivar tópico no tratamento da xerostomia numa população medicada com anti-hipertensivos
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Abstract(s)
Introdução: Cerca de 40% da população portuguesa é hipertensa. Os anti-hipertensivos são fármacos xerostomizantes. A xerostomia constitui um problema na saúde oral, no bem-estar e na qualidade de vida da população.
Objetivos: Compreender e avaliar a xerostomia e a prevalência de hipossalivação numa população medicada com anti-hipertensivos; verificar a eficácia de um sialogogo tópico nas alterações da taxa de fluxo salivar não estimulado (TFSNE) e estimulado (TFSE); avaliar a autoavaliação da qualidade de vida relacionada com saúde oral; avaliar a autopercepção da gravidade da xerostomia antes e depois da aplicação da terapêutica.
Métodos: Amostra de 32 indivíduos, selecionados aleatoriamente e divididos em 2 grupos (experimental e controlo). Aplicação de questionário com dados sociodemográficos, dados clínicos da hipertensão arterial, “Summated Xerostomia Inventory” (SXI-PL) e “The short version of Oral Health Impact Profile Questionnaire” (OHIP-14sp). Medição da tensão arterial, obtenção da TFSNE e da TFSE. Os dados recolhidos foram sujeitos a análise estatística com o SPSS®. Estudo aprovado pela Comissão de Ética do Instituto Universitário Egas Moniz e consentido pelos participantes.
Resultados: Amostra com média de idades de 67,46±12,36 anos e maioritariamente mulheres(72%). Na TFSNE obteve-se um aumento do fluxo salivar no grupo experimental de, em média, 0,03mL/min ± 0,03mL/min. Em relação ao SXI-PL, no grupo experimental, existiu um decréscimo, em média, de 1,38 ± 0,72 pontos na pontuação total e no grupo de controlo, existiu um decréscimo de, em média, 0,38 ± 0,62 pontos na pontuação total. No OHIP-14, observa-se um decréscimo (não significativo) de, em média, 1,56 ± 2,19 pontos na pontuação total no grupo de controlo e de 3,94 ± 2,76 pontos na pontuação total no grupo experimental.
Conclusão: A utilização de um estimulante salivar tópico com acido málico(1%), xilitol(10%) e fluoretos(0,05%) em forma de spray parece ter resultados positivos na TFSNE e na autopercepção da xerostomia.
Introduction: About 40% of the portuguese population is hypertensive. Antihypertensives are xerostomizing drugs. Xerostomia is a problem in oral health, well-being and quality of life of the population. Objectives: To understand and evaluate xerostomia and the prevalence of hyposalivation in a population medicated with antihypertensive drugs; to verify the efficacy of a topical sialogogue on changes in the rate of unstimulated (TFSNE) and stimulated (TFSE) salivary flow; to evaluate self-assessment of quality of life related to oral health; to evaluate self-perception of the severity of xerostomia before and after the application of therapy. Methods: Sample of 32 individuals, randomly selected and divided into 2 groups (experimental and control). Application of a questionnaire with sociodemographic data, clinical data of hypertension, “Summated Xerostomia Inventory” (SXI-PL) and “The short version of Oral Health Impact Profile Questionnaire” (OHIP-14sp). Blood pressure was measured, TFSNE and TFSE were obtained. The collected data were subjected to statistical analysis with SPSS®. Study approved by the Ethics Committee of Instituto Universitário Egas Moniz and consented by the participants. Results: Sample with a mean age of 67,46±12,36 years and mostly women (72%). In TFSNE we obtained an increased in salivary flow in the experimental group of, on average, 0.03mL/min±0.03mL/min. The SXI-PL score decreased in the experimental group by an average of 1.38±0.72 points. In the control group the total score decreased by an average of 0.38±0.62 points. In the OHIP-14sp, there was also a decrease (not significant) of, on average, 1.56±2.19 points in the total score in the control group and 3.94±2.76 points in the total score in the experimental group. Conclusion: The use of a topical salivary stimulant with malic acid (1%), xylitol (10%) and fluoride (0.05%) in spray form seems to have positive results on unstimulated saliva production and self-perception of xerostomia.
Introduction: About 40% of the portuguese population is hypertensive. Antihypertensives are xerostomizing drugs. Xerostomia is a problem in oral health, well-being and quality of life of the population. Objectives: To understand and evaluate xerostomia and the prevalence of hyposalivation in a population medicated with antihypertensive drugs; to verify the efficacy of a topical sialogogue on changes in the rate of unstimulated (TFSNE) and stimulated (TFSE) salivary flow; to evaluate self-assessment of quality of life related to oral health; to evaluate self-perception of the severity of xerostomia before and after the application of therapy. Methods: Sample of 32 individuals, randomly selected and divided into 2 groups (experimental and control). Application of a questionnaire with sociodemographic data, clinical data of hypertension, “Summated Xerostomia Inventory” (SXI-PL) and “The short version of Oral Health Impact Profile Questionnaire” (OHIP-14sp). Blood pressure was measured, TFSNE and TFSE were obtained. The collected data were subjected to statistical analysis with SPSS®. Study approved by the Ethics Committee of Instituto Universitário Egas Moniz and consented by the participants. Results: Sample with a mean age of 67,46±12,36 years and mostly women (72%). In TFSNE we obtained an increased in salivary flow in the experimental group of, on average, 0.03mL/min±0.03mL/min. The SXI-PL score decreased in the experimental group by an average of 1.38±0.72 points. In the control group the total score decreased by an average of 0.38±0.62 points. In the OHIP-14sp, there was also a decrease (not significant) of, on average, 1.56±2.19 points in the total score in the control group and 3.94±2.76 points in the total score in the experimental group. Conclusion: The use of a topical salivary stimulant with malic acid (1%), xylitol (10%) and fluoride (0.05%) in spray form seems to have positive results on unstimulated saliva production and self-perception of xerostomia.
Description
Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas Moniz
Keywords
Qualidade de vida Xerostomia Estimulante salivar Hipertensão arterial