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Publication
Relações entre experiências adversas na infância, funcionamento cognitivo e doença de Alzheimer : o papel da reserva cognitiva
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Abstract(s)
O envelhecimento populacional a nível mundial está a aumentar e com ele aumentam também os casos de demência. A demência é muito comum nas pessoas com idade mais avançada, sendo a DA uma das mais prevalentes. Na literatura, têm-se vindo a identificar fatores de risco associados à DA, estando entre eles, e mais recentemente, as EAI. A literatura tem demonstrado uma relação entre as duas e, apesar da evidência ainda escassa, os resultados disponíveis, são consistentes e corroboram esta relação. A RC é considerada um fator protetor, podendo ter um papel importante nesta relação enquanto protetora do declínio cognitivo. O presente estudo visou analisar a relação entre as EAI, a demência/declínio cognitivo, o funcionamento cognitivo e a RC. Recorreu-se a uma amostra constituída por 49 mulheres idosas integradas em dois grupos, mulheres saudáveis (n = 31) e mulheres com demência/declínio cognitivo (n = 18) com idades compreendidas entre os 65 e 99 anos. Os dados foram recolhidos através do questionário sociodemográfico, o MoCA, o DRS-2, o CTQ-SF, o CRS, o TeLPI, a EDG-15 e, por fim, a EAA-10. Os resultados evidenciaram que houve diferenças entre os grupos em relação ao funcionamento cognitivo, no entanto, não houve diferenças entre os grupos em relação às EAI e à RC. Além disso, verificou-se que a subescala da RC relativa à idade adulta tardia, as EAI e a negligência emocional foram um preditor significativo do funcionamento cognitivo. Os resultados destacam a importância de continuar a investigar a relação entre as EAI e a demência/declínio cognitivo, incluindo a RC como variável mediadora.
The world's ageing population is increasing and with it the number of cases of dementia. Dementia is very common in older people, and AD is one of the most prevalent. In the literature, risk factors associated with AD have been identified, including, most recently, ACEs. The literature has shown a relationship between the two and, although the evidence is still scarce, the available results are consistent and corroborate this relationship. CR is considered a protective factor and may play an important role in this relationship as a protector of cognitive decline. This study aimed to analyze the relationship between ACEs, dementia/cognitive decline, cognitive functioning and CR. The sample consisted of 49 elderly women divided into two groups: healthy women (n = 31) and women with dementia/cognitive decline (n = 18) aged between 65 and 99 years. Data was collected using a sociodemographic questionnaire, the MoCA, the DRS-2, the CTQ-SF, the CRS, the TeLPI, the GDS-15 and, finally, the AES-10. The results showed that there were differences between the groups in relation to cognitive functioning, however, there were no differences between the groups in relation to ACEs and CR. In addition, it was found that the CR subscale relating to late adulthood, ACEs and emotional neglect were a significant predictor of cognitive functioning. The results highlight the importance of continuing to investigate the relationship between ACEs and dementia/cognitive decline, including CR as a mediating variable.
The world's ageing population is increasing and with it the number of cases of dementia. Dementia is very common in older people, and AD is one of the most prevalent. In the literature, risk factors associated with AD have been identified, including, most recently, ACEs. The literature has shown a relationship between the two and, although the evidence is still scarce, the available results are consistent and corroborate this relationship. CR is considered a protective factor and may play an important role in this relationship as a protector of cognitive decline. This study aimed to analyze the relationship between ACEs, dementia/cognitive decline, cognitive functioning and CR. The sample consisted of 49 elderly women divided into two groups: healthy women (n = 31) and women with dementia/cognitive decline (n = 18) aged between 65 and 99 years. Data was collected using a sociodemographic questionnaire, the MoCA, the DRS-2, the CTQ-SF, the CRS, the TeLPI, the GDS-15 and, finally, the AES-10. The results showed that there were differences between the groups in relation to cognitive functioning, however, there were no differences between the groups in relation to ACEs and CR. In addition, it was found that the CR subscale relating to late adulthood, ACEs and emotional neglect were a significant predictor of cognitive functioning. The results highlight the importance of continuing to investigate the relationship between ACEs and dementia/cognitive decline, including CR as a mediating variable.
Description
Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas Moniz
Keywords
Experiências adversas na infância Doença de Alzheimer Demência Funcionamento cognitivo Reserva cognitiva