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Effects of multisession prefrontal cortex tDCS or taVNS on stress, perceived stress and sleep quality : a double-blind, randomized controlled study

datacite.subject.fosCiências Médicas::Ciências da Saúde
datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorReis, Laya Dalila dos
dc.contributor.authorGeneroso, Laura Pereira
dc.contributor.authorPereira, Gabrielly Santos
dc.contributor.authorBarú, João Paulo da Silva Teixeira
dc.contributor.authorCandido, Natalie Lange
dc.contributor.authorCapello, Maria Gabriela Maziero
dc.contributor.authorCastro, Renato Ortolani Marcondes de
dc.contributor.authorCardoso, Edvaldo José Rodrigues
dc.contributor.authorScoz, Robson Dias
dc.contributor.authorFerreira, Luciano Maia Alves
dc.contributor.authorSilva, Marcelo Lourenço da
dc.contributor.authorSilva, Josie Resende Torres da
dc.date.accessioned2026-03-25T15:35:34Z
dc.date.available2026-03-25T15:35:34Z
dc.date.issued2024-09
dc.description.abstractIntroduction: Chronic stress is a condition characterized by prolonged stimulation, leading to mental and physical weakness. It can have detrimental effects on individuals’ mental health and cognitive function, potentially causing various health issues. This article explores the potential of non-invasive neuromodulation techniques, specifically transcranial direct current stimulation (tDCS) and transcutaneous auricular vagus nerve stimulation (taVNS), in managing chronic stress and improving sleep quality.Methods: The study conducted a randomized, double-blinded, controlled trial with participants experiencing chronic stress. In total, 100 participants were randomly assigned to one of four conditions: the anodal tDCS group (n = 50), the sham tDCS group (n = 50), the taVNS group (n = 50), or the sham taVNS group (n = 50). Within each condition, participants received five sessions of either active treatment or sham treatment, with 20 min of tDCS over the dorsolateral prefrontal cortex (2 mA) for the tDCS groups, or taVNS on the left ear (20 Hz) for the taVNS groups. At baseline, post-intervention, and 4 weeks thereafter, we evaluated stress using the Lipp’s Inventory of Stress Symptoms for Adults (LSSI), perceived stress through the Perceived Stress Scale (PSS-10), and sleep quality via the Pittsburgh Sleep Quality Index (PSQI).Results: The tDCS and taVNS interventions resulted in reduced stress levels, improved sleep quality, and enhanced perception of stress.Discussion: These findings suggest that tDCS and taVNS hold promise as effective treatments for chronic stress, offering a safe and accessible approach to improving individuals’ wellbeing and overall quality of life.eng
dc.identifier.citationdos Reis LD, Pereira Generoso L, Pereira GS, Teixeira Barú JPS, Candido NL, Maziero Capello MG, de Castro ROM, Cardoso EJR, Scoz RD, Ferreira LMA, da Silva ML and da Silva JRT (2024) Effects of multisession prefrontal cortex tDCS or taVNS on stress, perceived stress and sleep quality: a double-blind, randomized controlled study. Front. Psychol. 15:1343413. doi: 10.3389/fpsyg.2024.1343413
dc.identifier.doi10.3389/fpsyg.2024.1343413
dc.identifier.issn1664-1078
dc.identifier.urihttp://hdl.handle.net/10400.26/62442
dc.language.isoeng
dc.peerreviewedyes
dc.publisherFrontiers Media
dc.relation.hasversionhttps://doi.org/10.3389/fpsyg.2024.1343413
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectchronic stress
dc.subjecttranscranial direct current stimulation
dc.subjecttranscutaneous auricular vagus nerve stimulation
dc.subjectsleep quality
dc.subjectneuromodulation
dc.titleEffects of multisession prefrontal cortex tDCS or taVNS on stress, perceived stress and sleep quality : a double-blind, randomized controlled studyeng
dc.typecontribution to journal
dspace.entity.typePublication
oaire.citation.startPage1343413
oaire.citation.titleFrontiers in Psychology
oaire.citation.volume15
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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