Publicação
High levels of physical activity reduce the esthetic durability of botulinum toxin type A : a controlled single-blind clinical trial
| datacite.subject.fos | Ciências Médicas::Ciências da Saúde | |
| datacite.subject.sdg | 03:Saúde de Qualidade | |
| dc.contributor.author | Morhy, Omar Neves | |
| dc.contributor.author | Sisnando, Andréa Lisbôa | |
| dc.contributor.author | Câmara-Souza, Mariana Barbosa | |
| dc.contributor.author | Carbone, Ana Claudia | |
| dc.contributor.author | Canales, Giancarlo De la Torre | |
| dc.date.accessioned | 2026-03-02T16:07:00Z | |
| dc.date.available | 2026-03-02T16:07:00Z | |
| dc.date.issued | 2023-07 | |
| dc.description.abstract | The present study aimed to evaluate the influence of physical activity on the durability of the esthetic effect of botulinum toxin type A (BoNT-A). Sixty female patients were allocated to three groups (n = 20) according to their physical activity level (PA): Low PA, Moderate PA, and High PA. All groups received a single injection of onabotulinumtoxinA, considering standardized doses in the frontalis (12U), corrugator supercilia (7U, each), and procerus muscles (4U). Outcomes were measured using electromyography (EMG), Merz 5-point scales, and Face-Q scales (perceived age and lines between eyebrows). A follow-up occurred after 30, 60, and 90 days. EMG results showed a significant decrease in muscle activity in the Low-PA group at all follow-ups compared with the other groups (p < 0.001). The Merz scale scores showed that the severity of forehead and glabellar lines significantly improved in the Low-PA group throughout this study compared with the other groups (p < 0.001). No significant differences between groups were found in the Face-Q scale for perceived age, while the Face-Q scale for lines between eyebrows showed better results for Low-PA (p < 0.01) and Moderate-PA (p < 0.01) groups compared to the High-PA group at the 30- and 90-day follow-ups. The durability of the esthetic effect of BoNT-A seems to be negatively influenced by the level of physical activity. | eng |
| dc.identifier.citation | Morhy ON, Sisnando AL, Câmara-Souza MB, Carbone AC, De la Torre Canales G. High Levels of Physical Activity Reduce the Esthetic Durability of Botulinum Toxin Type A: A Controlled Single-Blind Clinical Trial. Toxins. 2023; 15(7):463. https://doi.org/10.3390/toxins15070463 | |
| dc.identifier.doi | 10.3390/toxins15070463 | |
| dc.identifier.issn | 2072-6651 | |
| dc.identifier.uri | http://hdl.handle.net/10400.26/61926 | |
| dc.language.iso | eng | |
| dc.peerreviewed | yes | |
| dc.publisher | MDPI | |
| dc.relation.hasversion | https://doi.org/10.3390/toxins15070463 | |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | botulinum toxin | |
| dc.subject | electromyography | |
| dc.subject | physical activity | |
| dc.subject | wrinkles | |
| dc.title | High levels of physical activity reduce the esthetic durability of botulinum toxin type A : a controlled single-blind clinical trial | eng |
| dc.type | contribution to journal | |
| dspace.entity.type | Publication | |
| oaire.citation.issue | 7 | |
| oaire.citation.startPage | 463 | |
| oaire.citation.title | Toxins | |
| oaire.citation.volume | 15 | |
| oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 |