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A Enteropatia Inflamatória Crónica Canina (EICC) é uma patologia crónica que representa uma preocupação crescente em medicina veterinária. De facto, 10 a 20% dos casos observados em clínicas veterinárias de referência estão relacionados com distúrbios gastrointestinais. Trata-se de uma doença complexa e multifatorial que pode estar associada a diversos fatores, nomeadamente fatores genéticos, ambientais e imunitários. A EICC é uma doença que atualmente não tem cura e cujo tratamento visa o alívio dos sinais clínicos e a melhoria da qualidade de vida dos animais. A EICC é classificada de acordo com a resposta clínica ao tratamento. Embora alguns cães que sofrem de EICC necessitem de antibioterapia e imunossupressores, a grande maioria dos animais responde favoravelmente a modificações na dieta. De facto, a dieta é um elemento-chave nas EICC que pode desempenhar um papel benéfico ou eventualmente deletério no âmbito desta doença, já que alguns estudos demonstram que a dieta pode promover disbiose intestinal, mas também pode limitá-la, se for administrada corretamente. A disbiose corresponde a uma alteração significativa da composição e diversidade da microbiota intestinal que poderá estar associada ao desenvolvimento de inúmeras doenças, entre as quais a EICC. A comunidade científica tem-se preocupado em desenvolver terapêuticas inovadoras, mais seguras e eficazes que visam regular a composição da microbiota intestinal e, com isso, contribuírem para o tratamento de diversas patologias crónica, como a EICC. Nos últimos anos, surgiram novas opções de tratamento, como os probióticos, prebióticos, simbióticos, pós-bióticos e o transplante fecal que constituem estratégias terapêuticas promissoras no contexto desta patologia.
Canine Chronic Inflammatory Enteropathy (CCIE) is a chronic pathology that represents a growing concern in veterinary medicine. In fact, 10 to 20 % of cases seen in veterinary clinics are related to gastrointestinal disorders. It is a complex, multifactorial disease that can be associated with various factors, including genetic, environmental and immune factors. EICC is a disease that currently has no cure and whose treatment is aimed at relieving clinical signs and improving the quality of life of animals. EICC is categorised according to the clinical response to treatment. Although some dogs suffering from EICC require antibiotic therapy and immunosuppressants, the vast majority of animals respond favourably to dietary modifications. In fact, diet is a key element in EICC that can play a beneficial or possibly deleterious role in this disease, as some studies show that diet can promote intestinal dysbiosis, but can also limit it, if managed correctly. Dysbiosis corresponds to a significant alteration in the composition and diversity of the intestinal microbiota, which may be associated with the development of numerous diseases, including EICC. The scientific community has been concerned with developing innovative, safer and more effective therapies that aim to regulate the composition of the intestinal microbiota and thus contribute to the treatment of various chronic pathologies, such as CCIE. In recent years, new treatment options have emerged, such as probiotics, prebiotics, synbiotics, postbiotics and faecal transplantation, which are promising therapeutic strategies in the context of this pathology.
Canine Chronic Inflammatory Enteropathy (CCIE) is a chronic pathology that represents a growing concern in veterinary medicine. In fact, 10 to 20 % of cases seen in veterinary clinics are related to gastrointestinal disorders. It is a complex, multifactorial disease that can be associated with various factors, including genetic, environmental and immune factors. EICC is a disease that currently has no cure and whose treatment is aimed at relieving clinical signs and improving the quality of life of animals. EICC is categorised according to the clinical response to treatment. Although some dogs suffering from EICC require antibiotic therapy and immunosuppressants, the vast majority of animals respond favourably to dietary modifications. In fact, diet is a key element in EICC that can play a beneficial or possibly deleterious role in this disease, as some studies show that diet can promote intestinal dysbiosis, but can also limit it, if managed correctly. Dysbiosis corresponds to a significant alteration in the composition and diversity of the intestinal microbiota, which may be associated with the development of numerous diseases, including EICC. The scientific community has been concerned with developing innovative, safer and more effective therapies that aim to regulate the composition of the intestinal microbiota and thus contribute to the treatment of various chronic pathologies, such as CCIE. In recent years, new treatment options have emerged, such as probiotics, prebiotics, synbiotics, postbiotics and faecal transplantation, which are promising therapeutic strategies in the context of this pathology.
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Keywords
Enteropatia Inflamatória Crónica Cão Microbiota Intestinal Disbiose Dieta Estratégias Terapêuticas Inovadoras Prebióticos Probióticos Simbióticos Pós-Bióticos Transplante Fecal Chronic Inflammatory Enteropathy Dog Intestinal Microbiota Dysbiosis Diet Innovative Therapeutic Strategies Prebiotics Probiotics Symbiotics Post-Biotics Faecal Transplantation