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Selenium in dysphagic patients who underwent endoscopic gastrostomy for long term enteral feeding

dc.contributor.authorSantos, Carla Adriana
dc.contributor.authorFonseca, Jorge
dc.contributor.authorCarolino, Elisabete
dc.contributor.authorLopes, Teresa
dc.contributor.authorGuerreiro, António Sousa
dc.date.accessioned2017-08-03T15:20:51Z
dc.date.available2017-08-03T15:20:51Z
dc.date.issued2015-12
dc.description.abstract"BACKGROUND AND AIMS: endoscopic gastrostomy (PEG) patients usually present protein-energy malnutrition, but little is known about selenium deficiency. We aimed to assess serum selenium evolution when patients underwent PEG, after 4 and 12 weeks. We also evaluated the evolution of albumin, transferrin and Body Mass Index and the influence of the nature of the underlying disease. METHODS: a blood sample was obtained before PEG (T0), after 4 (T1) and 12 (T3) weeks. Selenium was assayed using GFAAS (Furnace Atomic Absorption Spectroscopy). The PEG patients were fed through homemade meals. Patients were studied as a whole and divided into two groups: head and neck cancer (HNC) and neurological dysphagia (ND). RESULTS: we assessed 146 patients (89 males), between 21-95 years old: HNC-56; ND-90. Normal values of selenium in 79% (n=115); low albumin in 77, low transferrin in 94, low values for both serum proteins in 66. Low BMI in 78. Selenium has slow evolution, with most patients still displaying normal Selenium at T3 (82%). Serum protein levels increase from T0 to T3, most patients reaching normal values. The nature of the underlying disease is associated with serum proteins but not with selenium. CONCLUSIONS: low serum selenium is uncommon when PEG is performed, after 4 and 12 weeks of enteral feeding and cannot be related with serum proteins levels or dysphagia cause. Enteral nutrition using customized homemade kitchen meals is satisfactory to prevent or correct Selenium deficiency in the majority of PEG patients."pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationNutr Hosp. 2015;32(6):2725-2733pt_PT
dc.identifier.doi10.3305/nh.2015.32.6.9756pt_PT
dc.identifier.issn1699-5198
dc.identifier.urihttp://hdl.handle.net/10400.26/18743
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherAula Médica Edicionespt_PT
dc.relation.publisherversionhttp://www.aulamedica.es/nh/pdf/9756.pdfpt_PT
dc.subjectSeleniumpt_PT
dc.subjectGastrostomypt_PT
dc.subjectPEGpt_PT
dc.subjectEnteral feedingpt_PT
dc.titleSelenium in dysphagic patients who underwent endoscopic gastrostomy for long term enteral feedingpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage2733pt_PT
oaire.citation.startPage2725pt_PT
oaire.citation.titleNutricion Hospitalariapt_PT
oaire.citation.volume32(6)pt_PT
rcaap.embargofctPolítica de copyright da editorapt_PT
rcaap.rightsrestrictedAccesspt_PT
rcaap.typearticlept_PT

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