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Publication
Potenciais efeitos adversos da terapêutica adjuvante do cancro cervico-facial, uma atualização
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Advisor(s)
Abstract(s)
Considerando que o número de pacientes com cancro de cabeça e pescoço (ou cancro
cervico-facial - CCF) se mantém significativo, é importante que o Médico Dentista
mantenha um conhecimento atualizado em oncologia.
O CCF é definido pela Classificação Internacional de Doenças (CID) como o conjunto de
tumores malignos que afetam qualquer localização supra-hioideia, excluindo tecidos
especializados cerebrais e oculares (incluindolocalização da cavidade oral, dos lábios à
garganta, amígdalas e a faringe) apresentando uma elevada taxa de mortalidade.
A ingestão de álcool e de tabaco, isolados ou em associação, são causas etiológicas envolvidas no aparecimento destes cancros. A infeção pelo vírus do papiloma humano
também tem sido apontado como importante fator etiológico para certas neoplasias, em
especial, quando os tumores estão localizados na orofaringe, e presentes em pessoas mais jovens.
As terapêuticas principais para o CCF compreendem a cirurgia, a radioterapia e a
quimioterapia, selecionado conforme a localização, tipo histológico do tumor, estádio
clínico e condições físicas do paciente. Na maioria dos casos, a cirurgia é o tratamento de eleição, associada ou não às outras opções de tratamento.
A radioterapia e quimioterapia são modalidades terapêuticas boa eficácia no tratamento
do cancro, porém promovem algumas reações adversas que atingem a cavidade oral
quando esses cancros estão localizados na região de cabeça e pescoço.
Desta forma, através de uma pesquisa bibliográfica de artigos em bases de dados, como
Scielo, Pubmed e B-ON, e outras fontes digitais, este trabalho tem como objetivo fazer
uma investigação bibliográfica de metodologia qualitativa sobre os efeitos adversos
orais da terapêutica adjuvante do cancro cervico-facial.
Considering that the number of patients with head and neck cancer (or cervico-facial cancer - CCF) remains significant, it is important that the Dentist maintains an updated knowledge in oncology. The CCF is defined by the International Classification of Diseases (ICD) as the set of malignant tumors that affect any suprahyoid location, excluding specialized brain and eye tissues (including location of the oral cavity, from lips to throat, tonsils and pharynx) presenting a high mortality rate. Ingestion of alcohol and tobacco, alone or in combination, are etiological causes involved in the appearance of these cancers. Infection with the human papilloma virus has also been identified as an important etiological factor for certain neoplasms, especially when the tumors are located in the oropharynx, and present in younger people. The main therapies for CCF include surgery, radiotherapy and chemotherapy, selected according to the location, tumor histological type, clinical stage and physical condition of the patient. In most cases, surgery is the treatment of choice, associated or not with other treatment options. Radiotherapy and chemotherapy are good therapeutic modalities in the treatment of cancer, however they promote some adverse reactions that reach the oral cavity when these cancers are located in the head and neck region. Thus, through a bibliographic research of articles in databases, such as Scielo, Pubmed and B-ON, and other digital sources, this work aims to make a literary review of qualitative methodology on the oral adverse effects of adjuvant therapy. cervico-facial cancer
Considering that the number of patients with head and neck cancer (or cervico-facial cancer - CCF) remains significant, it is important that the Dentist maintains an updated knowledge in oncology. The CCF is defined by the International Classification of Diseases (ICD) as the set of malignant tumors that affect any suprahyoid location, excluding specialized brain and eye tissues (including location of the oral cavity, from lips to throat, tonsils and pharynx) presenting a high mortality rate. Ingestion of alcohol and tobacco, alone or in combination, are etiological causes involved in the appearance of these cancers. Infection with the human papilloma virus has also been identified as an important etiological factor for certain neoplasms, especially when the tumors are located in the oropharynx, and present in younger people. The main therapies for CCF include surgery, radiotherapy and chemotherapy, selected according to the location, tumor histological type, clinical stage and physical condition of the patient. In most cases, surgery is the treatment of choice, associated or not with other treatment options. Radiotherapy and chemotherapy are good therapeutic modalities in the treatment of cancer, however they promote some adverse reactions that reach the oral cavity when these cancers are located in the head and neck region. Thus, through a bibliographic research of articles in databases, such as Scielo, Pubmed and B-ON, and other digital sources, this work aims to make a literary review of qualitative methodology on the oral adverse effects of adjuvant therapy. cervico-facial cancer
Description
Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas Moniz
Keywords
Cancro de cabeça e pescoço Terapêutica antineoplásica Efeitos adversos