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Publication
Disfunções da tiroide e o seu impacto em pacientes com Diabetes mellitus
| Name: | Description: | Size: | Format: | |
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| 1.6 MB | Adobe PDF |
Authors
Advisor(s)
Abstract(s)
Introdução: As disfunções da tiroide influenciam significativamente a saúde metabólica, especialmente em doentes com diabetes mellitus. A co-existência destas patologias é comum e tem importantes implicações clínicas. A interação entre estas doenças é intrincada, pois as disfunções tiroidianas podem afetar o controlo glicémico, enquanto o estado glicémico pode também influenciar a função da tiroide.
Objetivos: Este estudo teve como principal objetivo realizar uma revisão narrativa sobre as disfunções da tiroide e o seu impacto em pacientes com diabetes mellitus.
Métodos: A investigação baseou-se numa revisão narrativa de estudos científicos publicados nas bases de dados PubMed, ScienceDirect e Google Scholar. Foram incluídos artigos que analisaram a relação entre disfunções da tiroide e o seu impacto em doentes com diabetes mellitus, bem como artigos que discutiram o efeito do tratamento das disfunções tiroidianas no controlo glicémico. A pesquisa recaiu em estudos envolvendo doentes adultos diagnosticados com diabetes mellitus e distúrbios da tiroide, analisando o impacto do tratamento destes últimos nos níveis de glucose no sangue e na hemoglobina glicada A1c (HbA1c), que constitui um marcador do índice glicémico médio.
Resultados: Os estudos analisados indicaram uma associação clara entre as disfunções tiroidianas e o controlo da diabetes mellitus, evidenciando o impacto do hipotiroidismo e do hipertiroidismo no metabolismo da glucose. O hipotiroidismo, caracterizado pela redução da função tiroidiana, foi frequentemente associado a uma maior resistência à insulina, dificultando o controlo glicémico em doentes com diabetes tipo 2. O hipertiroidismo, por outro lado, pode aumentar a degradação de insulina e acelerar o metabolismo da glucose, dificultando o controlo glicémico em doentes com diabetes tipo 1 e tipo 2.
Conclusão: O diagnóstico atempado e o tratamento adequado das disfunções da tiroide em doentes com diabetes mellitus são essenciais para melhorar o controlo glicémico e minorar o risco de complicações.
Introduction: Thyroid disorders significantly influence metabolic health, especially in patients with diabetes mellitus. The co-existence of these pathologies is common and has important clinical implications. The interaction between these diseases is intricate, as thyroid disorders can affect glycemic control, while glycemic status can also influence thyroid function. Objectives: The main aim of this study was to conduct a narrative review on thyroid disorders and their impact on patients with diabetes mellitus. Methods: The research was based on a narrative review of scientific studies published in the PubMed, ScienceDirect, and Google Scholar databases. Articles that analyzed the relationship between thyroid disorders and their impact on patients with diabetes mellitus were included, as well as articles that discussed the effect of treating thyroid disorders on glycemic control. The research focused on studies with adult patients diagnosed with diabetes mellitus and thyroid disorders, analyzing the impact of thyroid treatment on blood glucose levels and hemoglobin A1c (HbA1c). Results: The studies analyzed indicated a clear association between thyroid dysfunction and the control of diabetes mellitus, highlighting the impact of hypothyroidism and hyperthyroidism on glucose metabolism. Hypothyroidism, characterized by reduced thyroid function, was often associated with greater insulin resistance, making glycemic control difficult in patients with type 2 diabetes. Hyperthyroidism, on the other hand, can increase insulin degradation and accelerate glucose metabolism, complicating glycemic control in patients with type 1 and type 2 diabetes. Conclusion: Timely diagnosis and appropriate treatment of thyroid dysfunction in patients with diabetes mellitus are essential to improve glycemic control and reduce the risk of complications.
Introduction: Thyroid disorders significantly influence metabolic health, especially in patients with diabetes mellitus. The co-existence of these pathologies is common and has important clinical implications. The interaction between these diseases is intricate, as thyroid disorders can affect glycemic control, while glycemic status can also influence thyroid function. Objectives: The main aim of this study was to conduct a narrative review on thyroid disorders and their impact on patients with diabetes mellitus. Methods: The research was based on a narrative review of scientific studies published in the PubMed, ScienceDirect, and Google Scholar databases. Articles that analyzed the relationship between thyroid disorders and their impact on patients with diabetes mellitus were included, as well as articles that discussed the effect of treating thyroid disorders on glycemic control. The research focused on studies with adult patients diagnosed with diabetes mellitus and thyroid disorders, analyzing the impact of thyroid treatment on blood glucose levels and hemoglobin A1c (HbA1c). Results: The studies analyzed indicated a clear association between thyroid dysfunction and the control of diabetes mellitus, highlighting the impact of hypothyroidism and hyperthyroidism on glucose metabolism. Hypothyroidism, characterized by reduced thyroid function, was often associated with greater insulin resistance, making glycemic control difficult in patients with type 2 diabetes. Hyperthyroidism, on the other hand, can increase insulin degradation and accelerate glucose metabolism, complicating glycemic control in patients with type 1 and type 2 diabetes. Conclusion: Timely diagnosis and appropriate treatment of thyroid dysfunction in patients with diabetes mellitus are essential to improve glycemic control and reduce the risk of complications.
Description
Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas Moniz
Keywords
Disfunções da tiroide Diabetes mellitus Controlo glicémico Hipotiroidismo Hipertiroidismo