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Síndrome de Sjögren e a prevalência da cárie dentária : uma revisão sistemática
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Abstract(s)
As evidências científicas relativas à prevalência de cárie dentária em indivíduos com Síndrome de Sjögren primária (SSp) são limitadas, pois muitas delas englobam a SSp não fazendo distinção entre a primária e secundária, tornando difícil a obtenção de conclusões definitivas.
Objetivo: Avaliar, através de uma revisão sistemática com meta-análise, a prevalência de cárie dentária em indivíduos adultos com SSp relativamente a populações controlo, a partir da evidência disponível na literatura científica.
Métodos: A pesquisa foi efetuada a partir de três bases de dados universais: PubMed, B-on e Scopus utilizando um algoritmo de pesquisa resultante da combinação das seguintes palavras chave: “Sjögren´s Syndrome”, “Adults”, “Caries” e “Prevalence”. Os gráficos meta-analíticos e estatísticas associadas foram realizados pelo software Open Meta Analyst. Em cada meta-análise foram avaliados os efeitos da idade, rácio masculino/feminino, DMFT e geografia no risco e prevalência de cárie dentária em indivíduos adultos com SSp. Os resultados estatísticos foram considerados significativos sempre que p< 0.05.
Resultados: No geral, a incidência média de cárie em indivíduos com SSp foi de 63.3%. Os indivíduos com SSp tiveram ainda em média mais 5.7 unidades de DMFT que o grupo controlo. Foi possível avaliar a incidência de cáries nos continentes Asiático e Americano. Verificou-se nos indivíduos com SSp um risco acrescido de ter cárie dentária na ordem das três vezes em relação a um indivíduo sem SSp.
Conclusão: Com o presente estudo, foi possível concluir que existe uma maior prevalência de cárie dentária em indivíduos com SSp que em indivíduos sem esta síndrome. Contudo, devido às limitações desta revisão, são necessários mais estudos que confirmem estes resultados.
Scientific evidence on the prevalence of dental caries in individuals with primary Sjögren's Syndrome (pSS) is quite scarce, as many of it encompass pSS without distinguishing between primary and secondary, thus making it difficult to obtain definitive conclusions. Objective: To assess, through a meta-analysis review, the prevalence of dental caries in adults with pSS compared to control samples, based on the available scientific evidence. Methods: The research was performed using three universal databases: PubMed, B-on and Scopus using a search algorithm resulting from the combination of the following keywords: “Sjögren's Syndrome”, “Adults”, “Caries” and “Prevalence”. The meta-analytic graphics and associated statistics were performed by the Open Meta Analyst software. In each meta-analysis, the effects of age, male/female ratio, DMFT and geography on the risk and prevalence of dental caries in adult individuals with pSS were evaluated. Statistical results were considered significant whenever p< 0.05. Results: In general, through the differences in DMFT means, it was possible to conclude that individuals with pSS have an average increase of 5.7 DMFT units compared to the control group. Regarding the incidence of caries in the Asian and American continents, there was a threefold increased risk of an individual with pSS having dental caries in relation to a healthy individual. Conclusion: With the present study it was possible to conclude that there is a higher incidence of dental caries in individuals with pSS compared to healthy individuals. However, further studies are needed to confirm these results.
Scientific evidence on the prevalence of dental caries in individuals with primary Sjögren's Syndrome (pSS) is quite scarce, as many of it encompass pSS without distinguishing between primary and secondary, thus making it difficult to obtain definitive conclusions. Objective: To assess, through a meta-analysis review, the prevalence of dental caries in adults with pSS compared to control samples, based on the available scientific evidence. Methods: The research was performed using three universal databases: PubMed, B-on and Scopus using a search algorithm resulting from the combination of the following keywords: “Sjögren's Syndrome”, “Adults”, “Caries” and “Prevalence”. The meta-analytic graphics and associated statistics were performed by the Open Meta Analyst software. In each meta-analysis, the effects of age, male/female ratio, DMFT and geography on the risk and prevalence of dental caries in adult individuals with pSS were evaluated. Statistical results were considered significant whenever p< 0.05. Results: In general, through the differences in DMFT means, it was possible to conclude that individuals with pSS have an average increase of 5.7 DMFT units compared to the control group. Regarding the incidence of caries in the Asian and American continents, there was a threefold increased risk of an individual with pSS having dental caries in relation to a healthy individual. Conclusion: With the present study it was possible to conclude that there is a higher incidence of dental caries in individuals with pSS compared to healthy individuals. However, further studies are needed to confirm these results.
Description
Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas Moniz
Keywords
Síndrome de Sjögren Adultos Cáries Prevalência