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Abstract(s)
A formação dos dentes é influenciada por diversos fatores, envolvendo interações complexas entre elementos genéticos, epigenéticos e ambientais ao longo do processo de desenvolvimento. O resultado dessas influências traduz-se em variações fenotípicas que abrangem o número, o tamanho, posição, erupção ou estrutura dentária. As anomalias dentárias são relativamente comuns e podem ser isoladas ou associadas a outros fatores.
Estas podem resultar da transmissão genética, estando presentes desde o nascimento devido a fatores hereditários dos pais.
O conhecimento destes síndromes permite que as crianças afetadas possam ser encaminhadas para especialistas em odontopediatria capazes de restaurar a função oral, sendo que uma deteção precoce proporciona um tratamento mais eficaz.
O objetivo desta revisão narrativa é explorar a forma como os fatores genéticos contribuem para o desenvolvimento de anomalias dentárias e como estas características são transmitidas de geração em geração.
Para a elaboração desta revisão bibliográfica, foram utilizadas como base de dados as plataformas: PubMed/Medline, Scielo, Google Acadêmico, B-on e Web of Science, tendo como objetivo reunir artigos que correspondem aos critérios essenciais para a elaboração desta tese.
The formation of teeth is influenced by various factors, involving complex interactions between genetic, epigenetic, and environmental elements throughout the developmental process. The outcome of these influences results in phenotypic variations that affect the number, size, position, eruption, or structure of teeth. Dental anomalies are relatively common and may occur in isolation or be associated with other factors. These anomalies can result from genetic transmission, being present from birth due to hereditary factors inherited from parents. Understanding these syndromes allows affected children to be referred to paediatric dental specialists capable of restoring oral function, as early detection provides more effective treatment. The aim of this narrative review is to explore how genetic factors contribute to the development of dental anomalies and how these traits are passed from one generation to the next. For the preparation of this bibliographic review, the following databases were used: PubMed/Medline, Scielo, Google Scholar, B-on, and Web of Science, with the goal of gathering articles that meet the essential criteria for the development of this thesis.
The formation of teeth is influenced by various factors, involving complex interactions between genetic, epigenetic, and environmental elements throughout the developmental process. The outcome of these influences results in phenotypic variations that affect the number, size, position, eruption, or structure of teeth. Dental anomalies are relatively common and may occur in isolation or be associated with other factors. These anomalies can result from genetic transmission, being present from birth due to hereditary factors inherited from parents. Understanding these syndromes allows affected children to be referred to paediatric dental specialists capable of restoring oral function, as early detection provides more effective treatment. The aim of this narrative review is to explore how genetic factors contribute to the development of dental anomalies and how these traits are passed from one generation to the next. For the preparation of this bibliographic review, the following databases were used: PubMed/Medline, Scielo, Google Scholar, B-on, and Web of Science, with the goal of gathering articles that meet the essential criteria for the development of this thesis.
Description
Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas Moniz
Keywords
Anomalias do desenvolvimento dentário Etiologia Hereditariedade Genética