Publicação
Chronic granulomatous disease associated with common variable immunodeficiency - 2 clinical cases
| dc.contributor.author | Pacheco, C | |
| dc.contributor.author | Morais, A | |
| dc.contributor.author | Rolo, R | |
| dc.contributor.author | Ferreira, L | |
| dc.contributor.author | Nabiço, R | |
| dc.contributor.author | Cunha, J | |
| dc.date.accessioned | 2014-02-14T12:50:43Z | |
| dc.date.available | 2014-02-14T12:50:43Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | INTRODUCTION: Chronic granulomatous disease associated with common variable immunodeficiency (GD-CVID), although well documented, is rare. Granulomatous lesions can affect several organs and are histologically indistinguishable from sarcoidosis. CLINICAL CASES: Case 1: A 39-year-old male patient with CVID, asymptomatic although with thrombocytopenia and mediastinal-hilar adenopathies. GD-CVID was diagnosed by bone marrow biopsy. Progressive clinical and radiological improvement was obtained with corticotherapy. Case 2: A 38-year-old male patient with CVID, suffered from asthenia, anorexia, myalgia, lower limbs edemas, and dry cough. He had mediastinal and bilateral hilar adenopathies within which biopsy revealed non-necrotizing granulomatous infiltrate. A spontaneous resolution was detected after 9 months of evolution. CONCLUSION: GD-CVID is rare and can mimetize other pathologies, namely, sarcoidosis; it should therefore be publicized and discussed so that it becomes a general clinical knowledge. | por |
| dc.identifier.citation | Rev Port Pneumol. 2014 Jan 22. pii: S0873-2159(13)00159-1. | por |
| dc.identifier.uri | http://hdl.handle.net/10400.26/5690 | |
| dc.language.iso | eng | por |
| dc.peerreviewed | yes | por |
| dc.publisher | Sociedade Portuguesa de Pneumologia | por |
| dc.subject | Doença Granulomatosa Crónica | por |
| dc.subject | Imunodeficiência de Variável Comum | por |
| dc.title | Chronic granulomatous disease associated with common variable immunodeficiency - 2 clinical cases | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |
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