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The effects of early rehabilitation on functional exercise tolerance in decompensated heart failure patients: Results of a multicenter randomized controlled trial (ERIC-HF study)

dc.contributor.authorDelgado, Bruno
dc.contributor.authorNovo, André
dc.contributor.authorLopes, Ivo
dc.contributor.authorRebelo, Carina
dc.contributor.authorAlmeida, Cecília
dc.contributor.authorPestana, Sandra
dc.contributor.authorGomes, Bárbara
dc.contributor.authorFroelicher, Erika
dc.contributor.authorKlompstra, Leonie
dc.date.accessioned2022-10-24T12:05:58Z
dc.date.available2022-10-24T12:05:58Z
dc.date.issued2022
dc.description.abstractObjective: To analyze (1) the effect of an aerobic training program on functional exercise tolerance in decompensated heart failure (DHF) patients; (2) to assess the effects of an aerobic training program on functional independence; and (3) dyspnea during activities of daily living. Design: A randomized controlled clinical trial with follow-up at discharge. Settings: Eight hospitals. Recruitment took place between 9/ 2017 and 3/2019. Group Assignments: Patients with DHF who were admitted to the hospital, were randomly assigned to usual rehabilitation care guideline recommended (control group) or aerobic training program (exercise group). Main outcome: Functional exercise tolerance was measured with a 6-min walking test at discharge. Results: In total 257 patients with DHF were included, with a mean age of 67±11 years, 84% (n=205) had a reduced ejection fraction and the hospital stay was 16±10 days. At discharge, patients in the intervention group walked further compared to the control group (278±117m vs 219±115m, p < 0.01) and this difference stayed significant after correcting for confounders (p < 0.01). A significant difference was found favoring the exercise group in functional independence (96±7 vs 93±12, p=0.02) and dyspnea associated to ADL (13±5 vs 17±7, p < 0.01) and these differences persisted after correcting for baseline values and confounders (functional independence p < 0.01; dyspnea associated with ADL p=0.02). Conclusion: The ERIC-HF program is safe, feasible, and effective in increasing functional exercise tolerance and functional independence in hospitalized patients admitted due to DHF.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationDelgado, B., Novo, A., Lopes, I., Rebelo, C., Almeida, C., Pestana, S., Gomes, B., Froelicher, E., & Klompstra, L. (2022). The effects of early rehabilitation on functional exercise tolerance in decompensated heart failure patients: Results of a multicenter randomized controlled trial (ERIC-HF study). Clinical Rehabilitation, 36(6), 813–821.pt_PT
dc.identifier.doi10.1177/02692155221088684pt_PT
dc.identifier.eissn1477-0873
dc.identifier.urihttp://hdl.handle.net/10400.26/42021
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSAGE Publicationspt_PT
dc.relation.publisherversionhttps://journals.sagepub.com/doi/full/10.1177/02692155221088684pt_PT
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/pt_PT
dc.subjectFunctional exercise tolerancept_PT
dc.subjectActivities of daily livingpt_PT
dc.subjectHeart diseasespt_PT
dc.subjectFunctional independencept_PT
dc.subjectHeart failurept_PT
dc.titleThe effects of early rehabilitation on functional exercise tolerance in decompensated heart failure patients: Results of a multicenter randomized controlled trial (ERIC-HF study)pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage821pt_PT
oaire.citation.issue6pt_PT
oaire.citation.startPage813pt_PT
oaire.citation.titleClinical Rehabilitationpt_PT
oaire.citation.volume36pt_PT
person.familyNameGomes
person.givenNameBárbara
person.identifier.orcid0000-0001-9312-8051
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationf128c193-26be-40c3-a936-21799ec8ca05
relation.isAuthorOfPublication.latestForDiscoveryf128c193-26be-40c3-a936-21799ec8ca05

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