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The effects of early rehabilitation on functional exercise tolerance in decompensated heart failure patients: Results of a multicenter randomized controlled trial (ERIC-HF study)
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Advisor(s)
Abstract(s)
Objective: To analyze (1) the effect of an aerobic training program on functional exercise tolerance in
decompensated heart failure (DHF) patients; (2) to assess the effects of an aerobic training program on
functional independence; and (3) dyspnea during activities of daily living.
Design: A randomized controlled clinical trial with follow-up at discharge.
Settings: Eight hospitals. Recruitment took place between 9/ 2017 and 3/2019.
Group Assignments: Patients with DHF who were admitted to the hospital, were randomly assigned to
usual rehabilitation care guideline recommended (control group) or aerobic training program (exercise
group).
Main outcome: Functional exercise tolerance was measured with a 6-min walking test at discharge.
Results: In total 257 patients with DHF were included, with a mean age of 67±11 years, 84% (n=205)
had a reduced ejection fraction and the hospital stay was 16±10 days. At discharge, patients in the intervention group walked further compared to the control group (278±117m vs 219±115m, p < 0.01)
and this difference stayed significant after correcting for confounders (p < 0.01). A significant difference
was found favoring the exercise group in functional independence (96±7 vs 93±12, p=0.02) and dyspnea
associated to ADL (13±5 vs 17±7, p < 0.01) and these differences persisted after correcting for baseline
values and confounders (functional independence p < 0.01; dyspnea associated with ADL p=0.02).
Conclusion: The ERIC-HF program is safe, feasible, and effective in increasing functional exercise tolerance
and functional independence in hospitalized patients admitted due to DHF.
Description
Keywords
Functional exercise tolerance Activities of daily living Heart diseases Functional independence Heart failure
Citation
Delgado, B., Novo, A., Lopes, I., Rebelo, C., Almeida, C., Pestana, S., Gomes, B., Froelicher, E., & Klompstra, L. (2022). The effects of early rehabilitation on functional exercise tolerance in decompensated heart failure patients: Results of a multicenter randomized controlled trial (ERIC-HF study). Clinical Rehabilitation, 36(6), 813–821.
Publisher
SAGE Publications