Publication
Determinants of self-medication with NSAIDs in a Portuguese community pharmacy
| dc.contributor.author | Nunes, Ana P. | |
| dc.contributor.author | Costa, Isabel M. | |
| dc.contributor.author | Costa, Filipa A. | |
| dc.date.accessioned | 2016-04-04T14:33:29Z | |
| dc.date.available | 2016-04-04T14:33:29Z | |
| dc.date.issued | 2016-01 | |
| dc.description | Licence CC BY-NC-ND http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt_PT |
| dc.description.abstract | "Background: Non-steroid anti-inflammatory drugs (NSAIDs) are a widely used therapeutic group in the world, and particularly in the Portuguese population. Objective: To compare NSAID’s use by prescription and self-medication acquisition and to determine the pattern of indication of NSAIDs, their usage profile and possible implications for patients’ safety. Methods: A cross-sectional design was used where individuals presenting at a community pharmacy requesting NSAIDs during the study period (one month) were invited to answer a face-to-face interview where socio-demographic characteristics, the indication pattern and previous experience of side effects were assessed. A follow-up interview was performed one week later to assess the incidence of adverse effects. The study was ethically approved. Results: A sample of 130 NSAIDs users was recruited, comprising mostly women (n=87; 66.9%), actively employed (n=77; 59.2%) and presenting a mean age of 49.5 years old (SD=20.49). An equal proportion of individuals acquired NSAIDs by self-medication and with medical prescription (n=65; 50%). Over 4/5 of patients (n=57; 87.7%) acquiring NSAIDs without a prescription were self-medicated by their own initiative, and only 10.8% (n=7) had been advised by the pharmacist. The most commonly acquired active substances were ibuprofen and diclofenac. Self-medicated users more frequently resorted to topical NSAIDs following short term treatments. The major underlying condition motivating NSAIDs sought were musculoskeletal disorders (45.0%), regardless of the regimen. An important proportion of prevalent users of NSAIDs reported previous experience of adverse effects (11.3%). One week after initiating NSAID therapy, a small proportion of patients reported incidence of adverse effects. Conclusion: Self-medication with NSAIDs is sought for numerous medical conditions. Reported adverse effects (prevalent and incident) confirm the need for a more rational use of NSAIDs and ongoing pharmacovigilance." | pt_PT |
| dc.identifier.citation | Nunes AP, Costa IM, Costa FA. Determinants of self-medication with NSAIDs in a Portuguese community pharmacy. Pharmacy Practice 2016 Jan-Mar;14(1):648. doi: 10.18549/PharmPract.2016.01.648 | pt_PT |
| dc.identifier.doi | 10.18549/PharmPract.2016.01.648 | pt_PT |
| dc.identifier.issn | 1886-3655 | |
| dc.identifier.uri | http://hdl.handle.net/10400.26/12862 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Centro de Investigaciones y Publicaciones Farmacéuticas | pt_PT |
| dc.relation.publisherversion | http://www.pharmacypractice.org/journal/index.php/pp/article/view/648 | pt_PT |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | pt_PT |
| dc.subject | Anti-Inflammatory Agents, Non-Steroidal | pt_PT |
| dc.subject | Drug-Related Side Effects and Adverse Reactions | pt_PT |
| dc.subject | Pharmacies | pt_PT |
| dc.subject | Cross-Sectional Studies | pt_PT |
| dc.subject | Portugal | pt_PT |
| dc.title | Determinants of self-medication with NSAIDs in a Portuguese community pharmacy | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.startPage | 648 | pt_PT |
| oaire.citation.title | Pharmacy Practice | pt_PT |
| oaire.citation.volume | 14(1) | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |