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Publication
Neurocosméticos : ligação cérebro-pele
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Advisor(s)
Abstract(s)
Os neurocosméticos representam uma abordagem emergente e inovadora nos cuidados dermatológicos, baseando-se na complexa interação entre o sistema nervoso e a pele, mediada pelo eixo Pele-Cérebro. Este eixo é regulado por diversos mediadores bioquímicos como neuropéptidos, hormonas e citocinas, que promovem uma comunicação bidirecional entre os dois sistemas. Formulados com ingredientes ativos, como péptidos, extratos marinhos e vegetais, os neurocosméticos interagem com a rede nervosa e com os neurotransmissores presentes na pele, modulando as suas respostas. Desta forma oferecem benefícios tanto estéticos quanto emocionais, tornando-se uma solução avançada e multifuncional para os cuidados de pele. Estes produtos destacam-se no contexto do envelhecimento cutâneo ao intervirem nos processos de neurodegeneração, inibirem neurotransmissores responsáveis pela contração muscular e modularem a síntese de colagénio e elastina. Consequentemente, contribuem para a atenuação de rugas e para o aumento da firmeza cutânea. Adicionalmente, regulam a libertação de substâncias inflamatórias como o cortisol, protegendo a pele do stress cutâneo, inflamação e do envelhecimento precoce. Alguns neurocosméticos também são capazes de atuar na sensibilidade cutânea, regulando a atividade de recetores associados a esta condição, aliviando assim, os seus sintomas. Além disto, promovem sensações de bem-estar ao estimularem a produção de β-endorfinas na pele e proporcionarem uma experiência multissensorial através de texturas e aromas que induzem sensações de conforto. Apesar dos potenciais benefícios, a classificação dos neurocosméticos pode ser ambígua, pois não se enquadram na definição estrita de cosmético estabelecida pelo Regulamento (CE) nº 1223/2009 do Parlamento Europeu e do Conselho, de 30 de novembro de 2009, relativo aos produtos cosméticos, colocando-os numa interseção entre cosméticos e produtos farmacêuticos.
Neurocosmetics represent an emerging and innovative approach to dermatological care, based on the complex interaction between the nervous system and the skin, mediated by the Skin-Brain axis. This axis is regulated by various biochemical mediators such as neuropeptides, hormones and cytokines, which promote bidirectional communication between the two systems. Formulated with active ingredients such as peptides, marine and plant extracts, neurocosmetics interact with the skin’s nerve network and neurotransmitters present in the skin, modulating their responses. In this way, they offer both aesthetic and emotional benefits, making them an advanced, multifunctional skincare solution. These products stand out in the context of skin aging by intervening in neurodegeneration processes, inhibiting neurotransmitters responsible for muscle contraction and modulating collagen and elastin synthesis. As a result, they help reduce wrinkles and increase skin firmness. In addition, they regulate the release of inflammatory substances, such as cortisol, protecting the skin from inflammation and premature aging. Some neurocosmetics are also able to act on skin sensitivity by regulating the activity of receptors associated with this condition, thereby relieving its symptoms. In addition, they promote a sense of well-being by stimulating the production of β-endorphins in the skin and providing a multisensory experience through textures and aromas that evoke feelings of comfort. Despite the potential benefits, the classification of neurocosmetics remains ambiguous, as they do not fall within the strict definition of cosmetics established by Regulation (EC) No. 1223/2009 of the European Parliament and of the Council of November 30, 2009 on cosmetic products. This places them at the intersection between cosmetics and pharmaceutical products.
Neurocosmetics represent an emerging and innovative approach to dermatological care, based on the complex interaction between the nervous system and the skin, mediated by the Skin-Brain axis. This axis is regulated by various biochemical mediators such as neuropeptides, hormones and cytokines, which promote bidirectional communication between the two systems. Formulated with active ingredients such as peptides, marine and plant extracts, neurocosmetics interact with the skin’s nerve network and neurotransmitters present in the skin, modulating their responses. In this way, they offer both aesthetic and emotional benefits, making them an advanced, multifunctional skincare solution. These products stand out in the context of skin aging by intervening in neurodegeneration processes, inhibiting neurotransmitters responsible for muscle contraction and modulating collagen and elastin synthesis. As a result, they help reduce wrinkles and increase skin firmness. In addition, they regulate the release of inflammatory substances, such as cortisol, protecting the skin from inflammation and premature aging. Some neurocosmetics are also able to act on skin sensitivity by regulating the activity of receptors associated with this condition, thereby relieving its symptoms. In addition, they promote a sense of well-being by stimulating the production of β-endorphins in the skin and providing a multisensory experience through textures and aromas that evoke feelings of comfort. Despite the potential benefits, the classification of neurocosmetics remains ambiguous, as they do not fall within the strict definition of cosmetics established by Regulation (EC) No. 1223/2009 of the European Parliament and of the Council of November 30, 2009 on cosmetic products. This places them at the intersection between cosmetics and pharmaceutical products.
Description
Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas Moniz
Keywords
Neurocosméticos Neuropéptidos Pele Sistema nervoso Cosmecêuticos