Mitochondrial DNA in human identification: a review

Amorim, António; Fernandes, Teresa; Taveira, Nuno

http://hdl.handle.net/10400.26/58087

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Authors

Amorim, António

Fernandes, Teresa

Taveira, Nuno

Abstract(s)

Mitochondrial DNA (mtDNA) presents several characteristics useful for forensic studies, especially related to the lack of recombination, to a high copy number, and to matrilineal inheritance. mtDNA typing based on sequences of the control region or full genomic sequences analysis is used to analyze a variety of forensic samples such as old bones, teeth and hair, as well as other biological samples where the DNA content is low. Evaluation and reporting of the results requires careful consideration of biological issues as well as other issues such as nomenclature and reference population databases. In this work we review mitochondrial DNA profiling methods used for human identification and present their use in the main cases of humanidentification focusing on the most relevant issues for forensics.

Keywords

Mitochondrial DNA Human identification Forensics

URI

http://hdl.handle.net/10400.26/58087

Citation

Amorim A, Fernandes T, Taveira N. 2019. Mitochondrial DNA in human identification: a review. PeerJ 7:e7314 https://doi.org/10.7717/peerj.7314

Publisher

Peer J

DOI

10.7717/peerj.7314

Collections

EM - Artigos Científicos

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