Publication
Cardiorenal syndrome: therapeutical challenge
| dc.contributor.advisor | Vieira, Maria JoĆ£o Nobre de Matos Pereira | |
| dc.contributor.author | Lopes, Sara Cristina Cerqueira | |
| dc.date.accessioned | 2016-12-29T10:35:26Z | |
| dc.date.available | 2016-12-29T10:35:26Z | |
| dc.date.issued | 2016-07-22 | |
| dc.description.abstract | Cardiorenal syndrome is described by the coexistence of cardiac and renal disease on the same individual, and it can affect both dogs and cats. The most consensual definition describes it as a āpathophysiologic disorder of the heart and kidneys whereby acute or chronic dysfunction of one of the organs causes acute or chronic dysfunction of the otherā. The interest, recognition of the importance and prevailing of this syndrome in veterinary medicine has grown and, recently, a committee of veterinarians specialized in cardiology and nephrology proposed that cardiorenal syndrome would be further designated as cardiovascular-renal axis disorders, classifying it in three types according to the disorders primary cause: CvRDH to heart as the primary failing organ, CvRDK to kidneys as the primary failing organ and CvRDO to when it has other causes. The current therapeutic for cardiorenal syndrome presents many variations, depending on the veterinarian preference as for what drugs should be used. However, there are certain assumptions that must be considered regarding this therapeutic challenge, and shouldnāt be undervalued since they take serious effect on the therapeutics success and, therefore, on the animal life expectancy. The dosages for the drugs used must suffer constant review, together with careful monitoring to the patients cardiac and renal functions, since the main challenge relies on the attempt to improve at the most one the organs function, without causing damage, or deterioration, to the other. This dissertation objective is to revise the current state of knowledge of cardiorenal syndrome in small animals, focusing on its diagnosis, classification and therapeutic challenge. | pt_PT |
| dc.description.abstract | A sĆndrome cardiorenal caracteriza-se pela coexistĆŖncia de doenƧa cardĆaca e renal num mesmo indivĆduo, podendo afetar cĆ£es e gatos. A definiĆ§Ć£o mais consensual descreve-o como um ādistĆŗrbio fisiopatolĆ³gico do coraĆ§Ć£o e dos rins, em que a afeĆ§Ć£o aguda ou crĆ³nica de um dos Ć³rgĆ£os, origina dano agudo ou crĆ³nico no outroā. O interesse e reconhecimento da importĆ¢ncia e prevalĆŖncia desta sĆndrome em medicina veterinĆ”ria tem sido crescente e, recentemente, um comitĆ© formado por mĆ©dicos veterinĆ”rios especialistas em cardiologia e nefrologia propuseram que a sĆndrome cardiorenal fosse designada como um distĆŗrbio do eixo cardiovascular-renal, classificando-a em trĆŖs tipos, consoante a origem do distĆŗrbio: CvRDH para o coraĆ§Ć£o como Ć³rgĆ£o de falĆŖncia primĆ”rio, CvRDK para rins como Ć³rgĆ£os de falĆŖncia primĆ”rio e CvRDO para quando Ć© originada por outras causas. A terapĆŖutica atual para a sĆndrome cardiorenal Ć© muito variada, e depende em muito da preferĆŖncia do mĆ©dico veterinĆ”rio quanto aos fĆ”rmacos utilizados. No entanto, hĆ” certas premissas que devem ser consideradas no que diz respeito a este desafio terapĆŖutico e que nĆ£o devem ser subvalorizadas, pois refletem-se seriamente no sucesso da terapĆŖutica e consequentemente na esperanƧa de vida do animal. As dosagens dos fĆ”rmacos utilizados devem sofrer uma revisĆ£o constante, acompanhada de uma cuidada monitorizaĆ§Ć£o das funƧƵes cardĆaca e renal do paciente, dado que o principal desafio reside na tentativa de melhorar ao mĆ”ximo a funĆ§Ć£o de um dos Ć³rgĆ£os sem causar dano, ou deterioraĆ§Ć£o, Ć funĆ§Ć£o do outro. Esta dissertaĆ§Ć£o tem como objetivo uma revisĆ£o do estado atual do conhecimento sobre a sĆndrome cardiorenal em animais de companhia, incidindo no seu diagnĆ³stico, classificaĆ§Ć£o e desafios terapĆŖuticos. | pt_PT |
| dc.identifier.tid | 201230160 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.26/17153 | |
| dc.language.iso | eng | pt_PT |
| dc.subject | Cardiorenal syndrome | pt_PT |
| dc.subject | Heart failure | pt_PT |
| dc.subject | Kidney failure | pt_PT |
| dc.subject | Therapeutics | pt_PT |
| dc.subject | SĆndrome cardiorenal | pt_PT |
| dc.subject | InsuficiĆŖncia cardĆaca | pt_PT |
| dc.subject | InsuficiĆŖncia renal | pt_PT |
| dc.subject | TerapĆŖutica | pt_PT |
| dc.title | Cardiorenal syndrome: therapeutical challenge | pt_PT |
| dc.type | master thesis | |
| dspace.entity.type | Publication | |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | masterThesis | pt_PT |
| thesis.degree.name | Medicina VeterinƔria | pt_PT |