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Publication
Etiologia e manifestações bioquímico fisiológicas da disfunção salivar
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Abstract(s)
A disfunção salivar é uma das patologias mais frequentes nos dias de hoje que afeta a qualidade de vida e bem-estar do paciente em causa. É definida como uma alteração na saliva produzida pelas glândulas major e minor, sendo a sua secreção controlada pelo sistema nervoso autónomo: alteração na composição (proteínas, iões orgânicos e inorgânicos), alteração na fluidez (quantidade de água) e/ou alteração na quantidade excretada, podendo ocorrer devido a diversos fatores etiológicos, como efeitos secundários medicamentosos e repercussões de diferentes tipos de terapias.
Tendo em conta que a cavidade oral é um dos principais meios de comunicação do meio interno do organismo humano com o meio externo, a saliva é um dos essenciais agentes na sua proteção devido à sua ação antimicrobiana, entre outras, onde o seu comprometimento levará a consequências a nível sistémico, assim como a nível oral, resultando em alterações das estruturas dentárias tal como dos tecidos moles e duros.
A presente revisão narrativa tem como objetivo correlacionar as diferentes etiologias da DS com as suas manifestações fisiológicas e bioquímicas. A revisão bibliográfica será fundamentada em artigos científicos publicados, disponíveis em diversas bases de dados, obedecendo a um limite temporal de dez anos.
Salivary dysfunction is one of the most common pathologies nowadays that affects the quality of life and well-being of the patient in question. It is defined as a change in saliva produced by the major and minor glands, with its secretion controlled by the autonomic nervous system: change in composition (proteins, organic and inorganic ions), change in fluidity (amount of water) and/or change in the amount excreted, which may occur due to various etiological factors, such as medication side effects and repercussions of different types of therapies. Taking into account that the oral cavity is one of the main means of communication between the internal environment of the human organism and the external environment, saliva is one of the essential agents in its protection due to its antimicrobial action, among others, where its impairment will lead to consequences at a systemic level, as well as at an oral level, resulting in changes to dental structures as well as soft and hard tissues. The present narrative review aims to correlate the different etiologies of salivary dysfunction with its physiological and biochemical manifestations. The bibliographic review will be based on published scientific articles, available in various databases, within a time limit of ten years.
Salivary dysfunction is one of the most common pathologies nowadays that affects the quality of life and well-being of the patient in question. It is defined as a change in saliva produced by the major and minor glands, with its secretion controlled by the autonomic nervous system: change in composition (proteins, organic and inorganic ions), change in fluidity (amount of water) and/or change in the amount excreted, which may occur due to various etiological factors, such as medication side effects and repercussions of different types of therapies. Taking into account that the oral cavity is one of the main means of communication between the internal environment of the human organism and the external environment, saliva is one of the essential agents in its protection due to its antimicrobial action, among others, where its impairment will lead to consequences at a systemic level, as well as at an oral level, resulting in changes to dental structures as well as soft and hard tissues. The present narrative review aims to correlate the different etiologies of salivary dysfunction with its physiological and biochemical manifestations. The bibliographic review will be based on published scientific articles, available in various databases, within a time limit of ten years.
Description
Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas Moniz
Keywords
Disfunção Saliva Xerostomia Glândula salivar