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Effectiveness and Safety of a Self-Management Program for Substance Addiction Consequences: A Pilot Clinical Trial

2026-08Artigo científico Acesso aberto
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dc.contributor.authorSeabra, Paulo
dc.contributor.authorSequeira, Rui
dc.contributor.authorSequeira, Ana
dc.contributor.authorFilipe, Miguel
dc.contributor.authorAmaral, Paula
dc.contributor.authorSequeira, Carlos
dc.contributor.authorNunes, Inês
dc.date.accessioned2026-09-14T11:04:39Z
dc.date.available2026-09-14T11:04:39Z
dc.date.issued2026-08
dc.description.abstractBackground: Harmful substance use affects millions of people, producing health and social consequences that require both professional support and effective self-management. This study piloted a self-management program targeting the consequences of substance addiction in adults enrolled in medication-based program. Methods: A parallel-group pilot trial compared the Self-Management Substance Addiction Consequences Program (ADS Program) with treatment as usual (TAU) to assess the program’s effectiveness and identify the need for adjustments to the intervention or the trial design. Seventy-two randomly selected adults enrolled for at least 5 weeks in medication-based program for alcohol or other drugs participated. Data were collected at baseline and after 8 to 21 weeks to assess effects on substance addiction consequences (SAC) and positive mental health (PMH). Results: Of the 236 patients screened, 72 were randomized: 38 to the ADS Program and 34 to TAU. Twenty-five participants completed the ADS Program (34.2% attrition), and 16 completed TAU (52% attrition). ADS participants attended more sessions (6 vs 2), although still fewer than planned. Participants in the ADS Program demonstrated significant reduction in SAC (paired t(24) = –5.718, P < .001, d = –1.169). Similar improvements were observed in the TAU group (paired t(15) = –6.357, P < .001, d = –1.580), with no significant differences between groups (P > .05). PMH also improved in both groups. The ADS group showed a statistically significant increase (paired t(20) = –3.945, P < .001, d = –0.861), whereas the TAU group demonstrated marginally non-significant improvement (paired t(11) = –2.170, P = .053, d = –0.626). No significant between-group differences were identified (P > .05). Conclusions: This pilot trial indicates that the ADS Program is feasible, safe, and potentially effective in supporting self-management of SAC. Findings suggest an adjusted duration of 6 to 18 weeks may be beneficial. Given the substantial dropout rate, further research with larger samples is needed to confirm effectiveness and improve retention.eng
dc.identifier.citationSeabra, P., Sequeira, R., Sequeira, A., Filipe, M., Amaral, P., Nunes, I., & Sequeira, C. (2026). Effectiveness and Safety of a Self-Management Program for Substance Addiction Consequences: A Pilot Clinical Trial. Substance use & addiction journal, 29767342261465527. Advance online publication. https://doi.org/10.1177/29767342261465527
dc.identifier.doi10.1177/29767342261465
dc.identifier.issn2976-7350
dc.identifier.urihttp://hdl.handle.net/10400.26/64592
dc.language.isoeng
dc.peerreviewedyes
dc.publisherSage
dc.relation.hasversionhttps://journals.sagepub.com/doi/10.1177/29767342261465527
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectnursing interventions
dc.subjectpilot randomized control trial
dc.subjectprogram evaluation
dc.subjectself-management
dc.subjectsubstance use disorder
dc.titleEffectiveness and Safety of a Self-Management Program for Substance Addiction Consequences: A Pilot Clinical Trialpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleSubstance Use & Addiction Journal
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85
person.familyNameSeabra
person.familyNameSequeira
person.familyNameCruz Sequeira
person.familyNameRobalo Nunes
person.givenNamePaulo
person.givenNameRui
person.givenNameCarlos Alberto
person.givenNameInês
person.identifier1178705
person.identifierK-5026-2013
person.identifier2664129
person.identifier.ciencia-id0F17-FF1F-E4FF
person.identifier.ciencia-idEC12-73D4-420B
person.identifier.ciencia-id1216-6764-F297
person.identifier.orcid0000-0001-8296-1021
person.identifier.orcid0000-0002-7573-2279
person.identifier.orcid0000-0002-5620-3478
person.identifier.orcid0000-0003-4718-8285
person.identifier.scopus-author-id57194716231
relation.isAuthorOfPublication159d6aa5-85ac-400d-bd74-4446fab18b50
relation.isAuthorOfPublication78de3d71-b302-4ea1-9956-d26b7952ee1e
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relation.isAuthorOfPublication2c7dd3c7-0316-426e-a515-e5c58e45de77
relation.isAuthorOfPublication.latestForDiscovery159d6aa5-85ac-400d-bd74-4446fab18b50

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