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Publication
As manifestações orais do vírus da hepatite C
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Advisor(s)
Abstract(s)
Descoberto em 1989, o Vírus da Hepatite C, designado mundialmente pela designação inglesa hepatitis C virus (HCV), ocupou desde então um lugar muito importante na hepato-gastroenterologia. O HCV é uma doença inflamatória do fígado, que pode levar a uma doença hepática aguda ou mesmo crónica. A sua gravidade varia entre uma forma leve, que dura apenas algumas semanas, e uma doença grave que pode persistir por toda a vida.
A sua infecção crónica acompanha-se de um grande número de doenças extrahepáticas.
Muitos destes são apenas casos relatados ou não são apoiados por provas suficientes. Outros, por outro lado, parecem estar claramente associados ao HCV, embora nem todos os mecanismos fisiopatológicos sejam compreendidos.
Esta dissertação define o que é o HCV, como suas fases de desenvolvimento, seus
modos de transmissão, replicação e sua prevalência a nível mundial. Além disso, seu
comportamento clínico, que envolve muitas manifestações na cavidade oral, como o
líquen plano, a síndrome de Sjögren e o cancro oral, será abordado, seguido de regras de higiene e assépsia necessárias na prática quotidiana em medicina dentária devido aos riscos de exposição ao sangue a que estão sujeitos os médicos dentistas, os assistentes dentários e doentes.
Discovered in 1989, the Hepatitis C Virus, known worldwide as the English hepatitis C virus (HCV), has since then occupied a very important place in hepatogastroenterology. HCV is an inflammatory liver disease that can lead to acute or even chronic liver disease. Its severity ranges from a mild form, which lasts only a few weeks, to a severe disease that can persist for a lifetime. Its chronic infection is accompanied by a large number of extrahepatic diseases. Many of these are only reported cases or are not supported by sufficient evidence. Others, on the other hand, appear to be clearly associated with HCV, although not all pathophysiological mechanisms are understood. This dissertation defines what the HCV is, as its development stages, its modes of transmission, replication and its prevalence worldwide. In addition, its clinical behaviour, which involves many manifestations in the oral cavity, such as lichen planus, Sjögren's syndrome and oral cancer, will be addressed, followed by the necessary hygiene and asepsis rules in daily dental practice due to the risks of exposure to blood to which dentists, dental practitioners and patients are subjected.
Discovered in 1989, the Hepatitis C Virus, known worldwide as the English hepatitis C virus (HCV), has since then occupied a very important place in hepatogastroenterology. HCV is an inflammatory liver disease that can lead to acute or even chronic liver disease. Its severity ranges from a mild form, which lasts only a few weeks, to a severe disease that can persist for a lifetime. Its chronic infection is accompanied by a large number of extrahepatic diseases. Many of these are only reported cases or are not supported by sufficient evidence. Others, on the other hand, appear to be clearly associated with HCV, although not all pathophysiological mechanisms are understood. This dissertation defines what the HCV is, as its development stages, its modes of transmission, replication and its prevalence worldwide. In addition, its clinical behaviour, which involves many manifestations in the oral cavity, such as lichen planus, Sjögren's syndrome and oral cancer, will be addressed, followed by the necessary hygiene and asepsis rules in daily dental practice due to the risks of exposure to blood to which dentists, dental practitioners and patients are subjected.
Description
Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas Moniz
Keywords
Vírus da hepatite C Manifestações orais Saúde oral Fatores de risco