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Blood pressure and tooth loss : a large cross-sectional study with age mediation analysis

2021-01Contribution to journal Open access
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datacite.subject.fosCiências Médicas
datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorMendes, José João
dc.contributor.authorViana, João
dc.contributor.authorCruz, Filipe
dc.contributor.authorPereira, Dinis
dc.contributor.authorFerreira, Sílvia
dc.contributor.authorPereira, Paula
dc.contributor.authorProença, Luís
dc.contributor.authorMachado, Vanessa
dc.contributor.authorBotelho, João
dc.contributor.authorRua, João
dc.contributor.authorDelgado, Ana Sintra
dc.date.accessioned2025-09-16T08:06:04Z
dc.date.available2025-09-16T08:06:04Z
dc.date.issued2021-01
dc.description.abstractWe aimed to investigate the association between blood pressure (BP) and tooth loss and the mediation effect of age. A cross-sectional study from a reference dental hospital was conducted from September 2017 to July 2020. Single measures of BP were taken via an automated sphygmomanometer device. Tooth loss was assessed through oral examination and confirmed radiographically. Severe tooth loss was defined as 10 or more teeth lost. Additional study covariates were collected via sociodemographic and medical questionnaires. A total of 10,576 patients were included. Hypertension was more prevalent in severe tooth loss patients than nonsevere tooth lost (56.1% vs. 39.3%, p < 0.001). The frequency of likely undiagnosed hypertension was 43.4%. The adjusted logistic model for sex, smoking habits and body mass index confirmed the association between continuous measures of high BP and continuous measures of tooth loss (odds ratio (OR) = 1.05, 95% CI: 1.03–1.06, p < 0.001). Age mediated 80.0% and 87.5% of the association between periodontitis with both systolic BP (p < 0.001) and diastolic BP (p < 0.001), respectively. Therefore, hypertension and tooth loss are associated, with a consistent mediation effect of age. Frequency of undiagnosed hypertension was elevated. Age, gender, active smoking, and BMI were independently associated with raised BP.eng
dc.identifier.citationMendes JJ, Viana J, Cruz F, Pereira D, Ferreira S, Pereira P, Proença L, Machado V, Botelho J, Rua J, et al. Blood Pressure and Tooth Loss: A Large Cross-Sectional Study with Age Mediation Analysis. International Journal of Environmental Research and Public Health. 2021; 18(1):285. https://doi.org/10.3390/ijerph18010285
dc.identifier.doi10.3390/ijerph18010285
dc.identifier.issn1660-4601
dc.identifier.urihttp://hdl.handle.net/10400.26/58665
dc.language.isoeng
dc.peerreviewedyes
dc.publisherMDPI
dc.relation.hasversionhttps://doi.org/10.3390/ijerph18010285
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjecthypertension
dc.subjecthigh blood pressure
dc.subjectoral health
dc.subjectdental medicine
dc.subjectpublic health
dc.subjectedentulism
dc.subjecttooth loss
dc.subjectage
dc.subjectmediation analysis
dc.titleBlood pressure and tooth loss : a large cross-sectional study with age mediation analysiseng
dc.typecontribution to journal
dspace.entity.typePublication
oaire.citation.issue1
oaire.citation.startPage285
oaire.citation.titleInternational Journal of Environmental Research and Public Health
oaire.citation.volume18
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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