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Ovarian sertoli-leydig cell tumour with heterologous elements of gastrointestinal type associated with elevated serum alpha-fetoprotein level: an unusual case and literature review
| dc.contributor.author | Horta, Mariana | |
| dc.contributor.author | Cunha, Teresa Margarida | |
| dc.contributor.author | Marques, Rita Canas | |
| dc.contributor.author | Félix, Ana | |
| dc.date.accessioned | 2016-10-04T14:33:33Z | |
| dc.date.available | 2016-10-04T14:33:33Z | |
| dc.date.issued | 2014 | |
| dc.date.updated | 2016-07-23T12:03:41Z | |
| dc.description.abstract | Here we describe the case of a 19-year-old woman with a poorly differentiated ovarian Sertoli-Leydig cell tumor and an elevated serum alphafetoprotein level. The patient presented with diffuse abdominal pain and bloating. Physical examination, ultrasound, and magnetic resonance imaging revealed a right ovarian tumor that was histopathologically diagnosed as a poorly differentiated Sertoli-Leydig cell tumor with heterologous elements. Her alpha-fetoprotein serum level was undetectable after tumor resection. Sertoli-Leydig cell tumors are rare sex cord-stromal tumors that account for 0.5% of all ovarian neoplasms. Sertoli-Leydig cell tumors tend to be unilateral and occur in women under 30 years of age. Although they are the most common virilizing tumor of the ovary, about 60% are endocrineinactive tumors. Elevated serum levels of alpha-fetoprotein are rarely associated with Sertoli-Leydig cell tumors, with only approximately 30 such cases previously reported in the literature. The differential diagnosis should include common alpha-fetoprotein-producing ovarian entities such as germ cell tumors, as well as other non-germ cell tumors that have been rarely reported to produce this tumor marker. | pt_PT |
| dc.identifier | 1943-0922 | en_US |
| dc.identifier.citation | Mariana Horta; Teresa Margarida Cunha; Rita Canas Marques; Ana Félix. Ovarian Sertoli-Leydig Cell Tumour with Heterologous Elements of Gastrointestinal Type Associated with Elevated Serum Alpha-Fetoprotein Level: An Unusual Case and Literature Review, Journal of Radiology Case Reports, 8, 11, 30-41, 2014. | pt_PT |
| dc.identifier.doi | 10.3941/jrcr.v8i11.2272 | pt_PT |
| dc.identifier.issn | 1943-0922 | |
| dc.identifier.uri | http://hdl.handle.net/10400.26/14946 | |
| dc.language.iso | eng | pt_PT |
| dc.title | Ovarian sertoli-leydig cell tumour with heterologous elements of gastrointestinal type associated with elevated serum alpha-fetoprotein level: an unusual case and literature review | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 41 | pt_PT |
| oaire.citation.issue | 11 | pt_PT |
| oaire.citation.startPage | 30 | pt_PT |
| oaire.citation.title | Journal of Radiology Case Reports | pt_PT |
| oaire.citation.volume | 8 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |
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