Synergistic Association of Genetic Variants with Environmental Risk Factors in Susceptibility to Essential Hypertension

Essential hypertension (EH) is a disease in which both environment and genes have an important role. This study was designed to identify the interaction model between genetic variants and environmental risk factors that most highly potentiates EH development.

Keywords

Case-Control Studies Diabetes Essential Hypertension Genetic Predisposition to Disease Genetic Variation Multifactor Dimensionality Reduction Obesity Polymorphism, Single Nucleotide Portugal Risk Factors Sterol Regulatory Element Binding Protein 1 Gene-Environment Interaction Madeira ADD1

URI

http://hdl.handle.net/10400.26/28007

Citation

Sousa, A. C., Mendonça, M. I., Pereira, A., Gouveia, S., Freitas, A. I., Guerra, G., ... & Pereira, D. (2017). Synergistic Association of Genetic Variants with Environmental Risk Factors in Susceptibility to Essential Hypertension. Genetic testing and molecular biomarkers, 21(10), 625-631.