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  • Effect of carrageenans on vegetable jelly in humans with hypercholesterolemia
    Publication . Valado, Ana; Pereira, Maria; Caseiro, Armando; Figueiredo, João; Loureiro, Helena; Almeida, Carla; Cotas, João; Pereira, Leonel
    Changes in lipid profile constitute the main risk factor for cardiovascular diseases. Algae extracted carrageenans are long-chain polysaccharides and their ability to form gels provides for the formation of vegetable jelly. The objective was to evaluate the bioactive potential of carrageenan (E407) in the lipid profile, after ingestion of jelly. A total of 30 volunteers of both sexes, aged 20-64 years and with total cholesterol (TC) values ≥200 mg/dL, who ingested 100 mL/day of jelly for 60 days, were studied. All had two venous blood collections: before starting the jelly intake and after 60 days. At both times, TC, high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C) and triglycerides (TG), were evaluated using commercial kits and spectrophotometer. The statistics were performed using the SPSS 25.0 software and p < 0.05 were considered statistically significant. Serum values after 60 days of jelly intake revealed a statistically significant decrease in TC levels (5.3%; p = 0.001) and LDL-C concentration (5.4%; p = 0.048) in females. The daily intake of vegetable jelly for 60 days showed a reduction in serum TC and LDL-C levels in women, allowing us to conclude that carrageenan has bioactive potential in reducing TC concentration.
  • Matrix metalloproteinase 9 and its tissue inhibitor 1 in obesity
    Publication . Lopes, Ana; Figueiredo, João; Santos, Rute; Loureiro, Helena; Castanheira, Joaquim; Osório, Nádia; Monteiro, Mário
  • Desnutrição em doentes idosos diabéticos: um problema atual
    Publication . Carvalho, M.C.; Loureiro, Helena; Figueiredo, João; Figueiredo, H.
    A prevalência de desnutrição em doentes hospitalizados (DDH) encontra-se descrita na literatura apresentando valores entre os 20 % e 50 % dependendo dos instrumentos de avaliação utilizados. A DDH está associada a um aumento das complicações, duração do tempo internamento e custos associados, comparativamente, com a ausência de desnutrição quer na admissão, quer no fim do internamento. Também a Diabetes tipo 2 (DMT2) é uma doença crónica com elevada expressão no doente idoso (DI) podendo contribuir para o aumento do risco da DDH não só pelo impacto negativo da diabetes no metabolismo dos Hidratos de Carbono mas também pela adoção de dietas rigorosas e pouco apelativas como medida terapêutica.
  • Malnutrition in diabetic elderly patients: an actual problem
    Publication . Loureiro, Helena; Carvalho, Maria do Carmo; Figueiredo, João; Matos, Luís
  • Interleukin 6 and Matrix Metalloproteinase 8 in obesity
    Publication . Figueiredo, João; Santos, Rute; Loureiro, Helena; Castanheira, Joaquim; Osório, Nádia; Monteiro, Mário; Caseiro, Armando
  • Association between serum levels of C-reactive protein and lipid profile
    Publication . Lopes, Ana; Figueiredo, João; Santos, Rute; Loureiro, Helena; Castanheira, Joaquim; Osório, Nádia; Monteiro, Mário; Caseiro, Armando