CHUSJ - Imunohemoterapia
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- Decision on conducting HCV Immunoblot and HCV Viral Load Tests Dependent upon the Result of the Screening TestsPublication . Bischoff, Francisco; Koch, Maria; Araújo, FernandoTesting for the presence of antibody to hepatitis C virus (anti-HCV) is recommended for initially identifying persons with HCV infection. According to the CDC guidelines it is appropriate to use a signal-to-cut-off value (S/CO) to limit the number of samples that needs supplemental testing. Moreover, the use of quantitative PCR assays for HCV RNA testing is fundamental for the assessment of chronic hepatitis C. The purpose of this study is to determine a specific value for a serological test for anti-HCV with a Positive Predictive Value (PPV) of 95% on positive HCV Immunoblot, and also determine a cut-off value for performing a clinically relevant HCV PCR. Were observed 415 individuals identified de novo as anti-HCV reactive, between 2009 and 2011. We estimate that a S/CO of 6.0 has a PPV of 99.83% being positive Immunoblot assay and that 99.49% of the samples with a S/CO ≤6.0 will have no detectable virus on PCR. Based on these results we propose a new algorithm for evaluation persons identified de novo as anti-HCV reactive: Immunoblot assay needs to be performed only for samples with a S/CO ≤6.0 and HCV PCR will be performed for persons with a S/CO >6.0. Using these criteria it would be possible to save € 9,000/year with acceptable clinical accuracy. This algorithm does not apply to rare cases of suspected acute HCV infection or suspicion of HCV infection in immunocompromised patients; for these cases we maintain the current approach of NAT testing for laboratory diagnosis of HCV infection.
- [Comparing the Application of Hema-Obs RSS to 250 Pregnancies from Obstetrics/Hematology Consultation in Centro Hospitalar São João, Portugal with the Application of Galit Sarig RSS to 90 Pregnancies from Rambam Health Care Campus, Israel]Publication . Salselas, Ana; Pestana, Inês; Bischoff, Francisco; Guimarães, Mariana; Andrade, Joaquim AguiarPregnant women with thromboembolic diseases, previous thrombotic episodes or thrombophilia family history were supervised in a multidisciplinary Obstetrics/ Hematology consultation in Centro Hospitalar São João EPE, Porto, Portugal. For the evaluation and medication of these women, a risk stratification scale was used.
- Nurses knowledge in Transfusion Medicine in a Portuguese university hospital: the impact of an educationPublication . Freixo, Ana; Matos, Isabel; Leite, Ana; Silva, Albina; Bischoff, Francisco; Carvalho, Milene; Monteiro, Carla; Ferreira, Alcídio; Fernandes, Susana; Lemos, Nuno; Delgado, Beatriz; Gomes, Helena; Regalado, Maria; Sabio, Federico; Cardoso, Filomena; Do Carmo Koch, Maria; Ramos, Lurdes; Araújo, Fernando
- Fiscalidade ao Serviço da Saúde Pública: A Experiência na Tributação das Bebidas Açucaradas em PortugalPublication . Goiana-da-Silva, Francisco; Nunes, Alexandre Morais; Miraldo, Marisa; Bento, Alexandra; Breda, João; Araújo, Fernando Ferreira
- A new interministerial strategy for the promotion of healthy eating in Portugal: implementation and initial resultsPublication . Graça, Pedro; Gregório, Maria João; de Sousa, Sofia Mendes; Brás, Sónia; Penedo, Tatiana; Carvalho, Telmo; Bandarra, Narcisa M.; Lima, Rui Matias; Simão, Ana Paula; Goiana-da-Silva, Francisco; Freitas, Maria Graça; Araújo, Fernando FerreiraTo describe the implementation, main intervention areas and initial results of the Integrated Strategy for the Promotion of Healthy Eating (EIPAS) in Portugal.