Percorrer por autor "Rodrigues, Carlota"
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- Diagnostic performance of AI-assisted software in sports dentistry : a validation studyPublication . Júdice, André; Brandão, Diogo; Rodrigues, Carlota; Simões, Cátia; Nogueira, Gabriel; Machado, Vanessa; Ferreira, Luciano Maia Alves; Ferreira, Daniel; Proença, Luís; Botelho, João; Fine, Peter; Mendes, José JoãoArtificial Intelligence (AI) applications in sports dentistry have the potential to improve early detection and diagnosis. We aimed to validate the diagnostic performance of AI-assisted software in detecting dental caries, periodontitis, and tooth wear using panoramic radiographs in elite athletes. This cross-sectional validation study included secondary data from 114 elite athletes from the Sports Dentistry department at Egas Moniz Dental Clinic. The AI software’s performance was compared to clinically validated assessments. Dental caries and tooth wear were inspected clinically and confirmed radiographically. Periodontitis was registered through self-reports. We calculated sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), as well as the area under the curve and respective 95% confidence intervals. Inter-rater agreement was assessed using Cohen’s kappa statistic. The AI software showed high reproducibility, with kappa values of 0.82 for caries, 0.91 for periodontitis, 0.96 for periapical lesions, and 0.76 for tooth wear. Sensitivity was highest for periodontitis (1.00; AUC = 0.84), moderate for caries (0.74; AUC = 0.69), and lower for tooth wear (0.53; AUC = 0.68). Full agreement between AI and clinical reference was achieved in 86.0% of cases. The software generated a median of 3 AI-specific suggestions per case (range: 0–16). In 21.9% of cases, AI’s interpretation of periodontal level was deemed inadequate; among these, only 2 cases were clinically confirmed as periodontitis. Of the 34 false positives for periodontitis, 32.4% were misidentified by the AI. The AI-assisted software demonstrated substantial agreement with clinical diagnosis, particularly for periodontitis and caries. The relatively high false-positive rate for periodontitis and limited sensitivity for tooth wear underscore the need for cautious clinical integration, supervision, and further model refinements. However, this software did show overall adequate performance for application in Sports Dentistry.
- Post-market non-controlled study on the clinical safety of a synthetic calcium phosphate ceramic in alveolar bone regeneration : a 6-month prospective studyPublication . Silva, Nuno; Rodrigues, Carlota; Lobito, Angel; Azul, António Mano; Trancoso, Pedro Ferreira; Machado, Vanessa; Botelho, JoãoThis prospective, single-arm post-market study aimed to evaluate the clinical safety and performance of a synthetic calcium phosphate ceramic used in alveolar bone regeneration procedures. Eighty adult patients requiring bone augmentation were treated with β-tricalcium phosphate (β-TCP) under routine clinical indications. Surgical approaches were adapted to defect morphology. Safety outcomes included adverse events (AEs) and device deficiencies (DDs), while performance outcomes focused on two-dimensional radiographic bone assessment. Radiographic bone consolidation was defined as continuous trabecular radiopacity without radiolucent defects or clinical signs of infection. Patients were followed for six months post-surgery, with clinical and radiographic evaluations, as well as assessment of oral health-related quality of life (OHIP-14). All 80 patients (mean age: 47.2 ± 18.9 years; 51% male) completed the immediate postoperative assessment. Eleven DDs (granule loss) were observed postoperatively (13.8%) and no AEs. At six months, 71 patients (88.8%) completed follow-up. Radiographic bone repair was confirmed in all cases clinically observed and with follow-up X-ray (100%). No AEs or DDs reported (AE-free rate: 100%) at this follow-up. The median OHIP-14 score improved significantly at six months (p = 0.037), indicating better self-reported oral health. Given the observational design, absence of a control group, and partial reliance on non-radiographic follow-up, these findings should be interpreted with caution. Within these limitations, the synthetic calcium phosphate ceramic demonstrated a favorable short-term safety profile and apparent bidimensional radiographic signs of clinical performance under real-world conditions, rather than definitive evidence of effectiveness. Further controlled studies incorporating histological and volumetric analyses are warranted to confirm its regenerative potential.