Percorrer por autor "Ravazzi, Glória"
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- Effect of respiratory therapy on patients with sleep bruxism and associated respiratory events: study protocol for a randomized controlled clinical trial.Publication . Cavalcante-Leão, Bianca; Neto, José; Ravazzi, Glória; Fischer, Anne; Abdula, Yasmin; Cruz, Miguel; Santos, Rosane Sampaio; Zeigelboim, BiancaAim: The aim of this study will be to perform respiratory physiotherapy on patients with sleep bruxism and associated respiratory events (apnea and hypopnea). Methodology: The study will be a randomized, controlled, doubleblind, clinical trial with a sample of individuals with sleep bruxism and associated respiratory events. Respiratory (inspiratory and/or expiratory) physiotherapy will be performed using the THRESHOLD IMT and PEP and the results will be compared to a placebo group. Discussion: Regarding respiratory events, there is a broad variety of possible treatments for sleep apnea depending on the physiopathology, severity and patient preference, with CPAP considered the gold standard. However, data on CPAP are inconsistent, with adherence to therapy reported to be between 45 and 89%. Thus, other forms of treatment are proposed, including respiratory training. Understanding obstructive sleep apnea syndrome as the loss of the dilation strength of the pharynx and the inability to maintain the path open for air, respiratory muscle training could assist in increasing dilation strength, enabling the passage of air during sleep. Taking into consideration that sleep bruxism may be associated with events of apnea and hypopnea, the intervention to treat obstructive respiratory events related to sleep may have a positive impact on events related to sleep bruxism (rhythmic activity of the masticatory muscles). To determine this, we will measure the apnea/hypopnea index (AHI) and number of contractions of the masseter muscle (characteristic of the activity of bruxism) before and after the intervention using polysomnography.
- Effects of respiratory training on obstructive sleep apnea: systematic review and meta-analysisPublication . Cavalcante-Leão, Bianca; Araujo, Cristiano; Ravazzi, Glória; Basso, Isabela; Guariza‑Filho, Odilon; Taveira, Karinna; Santos, Rosane Sampaio; Neto, José; Zeigelboim, BiancaPurpose: This systematic review sought to answer the following focused question: “What are the effects of respiratory training devices on obstructive sleep apnea (OSA) outcomes in adults?” Methods: The acronym “PICOS” was used to determine eligibility criteria, which consists of (P population) = adults with mild to moderate OSA, (I intervention) = spirometry devices or breathing exercises, (C comparison) = compared to no breathing exercises in adults (> 18 years) with mild to moderate OSA, (O outcomes) = improved sleep quality (sleep quality indexes) and improved apnea-hypopnea indexes (AHI), (S study types) = randomized, pseudo-randomized, and nonrandomized clinical trials. The search was performed in the following databases: PubMed/Medline, LILACS, Scopus, Web of Science, Scopus, and Cochrane Library, in addition to gray literature through Google Scholar, Proquest, and Open Grey. The risk of bias was assessed using the Cochrane Collaboration tool. The certainty of the evidence was assessed using the GRADE tool. Meta-analyses of random effects were performed for the outcomes of interest. Results: A total of 1171 references were found. Applying the eligibility criteria, six studies were included in qualitative synthesis. Expiratory exercises showed a decrease in the apnea–hypopnea index (AHI) when compared to baseline (MD = − 8.4; 95% CI = − 12.4 to − 4.4; I2 = 19%). There was a decrease in values compared to baseline (MD = − 4.4; 95% CI = − 8.2 to − 0.6; I2 = 0%) for the Epworth Sleepiness Scale (ESS), when considering the inspiratory exercises. Both groups of breathing exercises showed a significant decrease in the mean index assessed by the Pittsburgh Sleep Quality Index (PSQI). Conclusion: Results of this meta-analysis suggests that breathing exercises lead to a measurable improvement in AHI for patients with mild to moderate OSA, as well as an improvement in sleep quality and daytime sleepiness.
- Front lines of the COVID-19 pandemic: what is the effectiveness of using personal protective equipment in health service environments?: a systematic reviewPublication . Araujo, Cristiano; Guariza‑Filho, Odilon; Gonçalves, Flavio; Basso, Isabela; Schroder, Angela; Cavalcante‑Leão, Bianca; Ravazzi, Glória; Zeigelboim, Bianca; Neto, José; Sampaio Santos, RosanePurpose: This systematic review aimed to evaluate the effectiveness of the use of personal protective equipment (PPE) in closed environments, similar to waiting or exam rooms of healthcare facilities, in the face of exposure to a bioaerosol. Methods: Combinations of words were selected for six electronic databases and for the gray literature. To consider the eligibility of the studies to be included/excluded, the acronym “PECOS” was used: humans and/or experimental models that simulate aerosol (Population); aerosol exposure and the use of masks/respirators (exposition/intervention); controlled or not controlled (comparison); effectiveness of PPE and the receiver exposure (outcomes); and randomized clinical studies or not, observational or laboratory simulation studies (Studies design). Results: A total of 4820 references were retrieved by the search strategy. Thirty-five articles were selected for complete reading, of which 13 articles were included for qualitative synthesis. A surgical mask or N95 respirator reduced the risk of transmission, even over short distances. The use of masks, even those with less filtering power, when used by all individuals in the same environment is more effective in reducing risk than the use of respirators with high filtering power for only some of the individuals present. Conclusion: The use of mask in closed environments is effective in reducing the risk of transmission and contagion of a contaminated bioaerosol, with greater effectiveness when these devices are used by the source and receiver, regardless of the equipment’s filtering power.
- Is there scientific evidence of the mouthwashes effectiveness in reducing viral load in Covid-19?: a systematic reviewPublication . Cavalcante-Leão, Bianca; Araujo, Cristiano; Basso, Isabela; Schroder, Angela; Guariza-Filho, Odilon; Ravazzi, Glória; Gonçalves, Flavio; Zeigelboim, Bianca; Sampaio Santos, Rosane; Neto, José StechmanBackground: The aim of this research is to verify whether there is evidence in the literature regarding the decrease in viral load present in saliva after using three types of mouthwashes. Material and Methods: Clinical and/or in vitro experimental studies that have used mouthwashes as a form of intervention to reduce the viral load in saliva were included. Combinations of words and appropriate truncations were adapted for each of the seven selected electronic bases including grey literature. Results: The selection of articles was carried out in two phases by two independent reviewers. After removing duplicate articles, 1245 references were maintained, and 2 articles were included in the Systematic Review. Both studies were performed in vitro and tested the virucidal action of the PVP-I solution for mouthwash at two different concentrations, 1% without dilution and 7% with 1:30 dilution, on the SARS-CoV and MERS-CoV viruses. Both showed a viral reduction of ≥ 99.99% with 15 s exposure. Conclusions: Based on the evidence currently available in the literature, PVP-I, at concentrations of 1 and 7%, appears to be the most effective mouthwash for reducing the viral load of COVID-19 present in human saliva. However, the guidelines for dental care refer to the use of hydrogen peroxide but there is insufficient scientific evidence to support this recommendation.