Percorrer por autor "Ramalho, Renata"
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- Avaliação da ingestão de cafeínaPublication . Pereira, Diana; Morcocean, Lídia; Silva, Mariana; Gomes, Raquel; Ramalho, Renata; Auxtero, Maria Deolinda
- Composição corporal e suplementos alimentaresPublication . Palma, Beatriz; Marques, Catarina; Quendera, Catarina; Costa, Inês; Figueiredo, Maria Leonor; Ramalho, Renata; Auxtero, Maria Deolinda
- Docosahexaenoic acid supplementation for children with attention deficit hyperactivity disorder: a comprehensive review of the evidencePublication . Ramalho, Renata; Pereira, Ana Colaço; Vicente, Filipa; Pereira, PaulaAttention deficit hyperactivity disorder (ADHD) is considered the most common behavioural disorder in school-age children. ADHD is a complex and multifactorial disorder characterised by a variety of symptoms, including concentration problems, excessive motor activity and impulsivity which interferes with execution of simple school tasks. Diagnosis has been essentially subjective, since no specific laboratory tests are available. However, ADHD remains overdiagnosed, probably due to social pressures for children to be successful in school from an early age, which leads parents to seek medical support. Although therapeutic approaches for ADHD have been essentially pharmacologic, in recent years several studies were performed to investigate the role of nutrition, especially omega 3 polyunsaturated fatty acid (omega 3-PUFA), in the development and treatment of this disorder. In this review, the authors gathered the most relevant evidence regarding omega 3-PUFA, mainly docosahexaenoic acid, as coadjutant or as a single therapy, in the management of ADHD symptoms. The authors also reviewed this disorder's current medical and therapeutic features.
- Effect of different cooking methods on the content of total vitamin C, ascorbic acid and dehydroascorbic acid of the galega kalePublication . Vieira, Carolina; Silva, Marta da; Simões, Margarida; Rodrigues, Gonçalo; Albuquerque, Tânia; Ramalho, Renata; Pereira, Paula
- Food intake assessment and anthropometric characterisation of teenage gymnastsPublication . Holanda, Marcela; Lavado, Patrícia; Vicente, Filipa; Ramalho, Renata; Pereira, Paula
- Ketogenic diet and neuroinflammation : implications for neuroimmunometabolism and therapeutic approaches to refractory epilepsyPublication . Guerreiro, Daniela; Almeida, Anabela; Ramalho, RenataRefractory epilepsy, characterized by seizures that do not respond to standard antiseizure medications, remains a significant clinical challenge. The central role of the immune system on the occurrence of epileptic disorders has been long studied, but recent perspectives on immunometabolism and neuroinflammation are reshaping scientific knowledge. The ketogenic diet and its variants have been considered an important medical nutrition therapy for refractory epilepsy and may have a potential modulation effect on the immune system, specifically, on the metabolism of immune cells. In this comprehensive review, we gathered current evidence-based practice, ketogenic diet variants and interventional ongoing clinical trials addressing the role of the ketogenic diet in epilepsy. We also discussed in detail the ketogenic diet metabolism and its anticonvulsant mechanisms, and the potential role of this diet on neuroinflammation and neuroimmunometabolism, highlighting Th17/Treg homeostasis as one of the most interesting aspects of ketogenic diet immune modulation in refractory epilepsy, deserving consideration in future clinical trials.
- Lower calcium and iron intake in adolescent gymnasts : a case of concern for youth sports nutritionPublication . Vicente, Filipa; Holanda, Marcela; Ramalho, Renata; Mendes, João; Marques-Vidal, Pedro; Pereira, PaulaObjectives: Diet is important for the appropriate development and maturation of young amateur athletes. The aim of this study was to determine whether young gymnasts were consuming adequate amounts of nutrients, particularly calcium and iron. Methods: This cross-sectional survey was conducted in Portugal's Almada and Lisbon regions in 2020. To determine if participants’ diet was adequate, weight, height, and skinfold measurements were taken. Dietary consumption was examined using two 24-h recalls. We collected data from 66 participants (60% females, 12–18 y of age), of whom 82% had normal weight and 39% had ideal body fat. Results: The daily total energy intake (TEI) was1605 ± 601 kcal. Of the TEI, 19%, 31%, and 50% were comprised of protein, fat, and carbohydrates, respectively. The most often consumed protein sources were poultry and ultra-processed meat products (52% and 45%, respectively). The average daily consumption of calcium and iron was 626 ± 293 and 9 ± 3 mg, respectively. Only 2 of the 66 participants had calcium intake within recommended levels, and 1of 5 had iron intake within recommended levels, the percentage of which was lower in girls than boys (7.5% versus 38.5%, P < 0.05). Conclusions: Despite having a sufficient macronutrient distribution, Portuguese gymnasts consume a high amount of ultra-processed items and a low amount of calcium and iron. The low proportion of female gymnasts with adequate iron consumption is cause for worry in sports nutrition.
- Massa de Malagueta : tradition with a twistPublication . Correia, Lia; Mendes, Inês; Ortiz, Sofia; Ramalho, Renata; Pereira, Paula
- Nutritional senolytics and senomorphics : implications to immune cells metabolism and aging – from theory to practicePublication . Luís, Carla; Maduro, Ana T.; Pereira, Paula; Mendes, José João; Soares, Raquel; Ramalho, RenataAging is a natural physiological process, but one that poses major challenges in an increasingly aging society prone to greater health risks such as diabetes, cardiovascular disease, cancer, frailty, increased susceptibility to infection, and reduced response to vaccine regimens. The loss of capacity for cell regeneration and the surrounding tissue microenvironment itself is conditioned by genetic, metabolic, and even environmental factors, such as nutrition. The senescence of the immune system (immunosenescence) represents a challenge, especially when associated with the presence of age-related chronic inflammation (inflammaging) and affecting the metabolic programming of immune cells (immunometabolism). These aspects are linked to poorer health outcomes and therefore present an opportunity for host-directed interventions aimed at both eliminating senescent cells and curbing the underlying inflammation. Senotherapeutics are a class of drugs and natural products that delay, prevent, or reverse the senescence process – senolytics; or inhibit senescence-associated secretory phenotype – senomorphics. Natural senotherapeutics from food sources – nutritional senotherapeutics – may constitute an interesting way to achieve better age-associated outcomes through personalized nutrition. In this sense, the authors present herein a framework of nutritional senotherapeutics as an intervention targeting immunosenescence and immunometabolism, identifying research gaps in this area, and gathering information on concluded and ongoing clinical trials on this subject. Also, we present future directions and ideation for future clinical possibilities in this field.
- Opuntia ficus-indica (L.) Mill. : a multi-benefit potential to be exploitedPublication . Silva, Mafalda Alexandra; Albuquerque, Tânia Gonçalves; Pereira, Paula; Ramalho, Renata; Vicente, Filipa; Oliveira, Maria Beatriz P. P.; Costa, Helena S.Consumer interest in foods with enhanced nutritional quality has increased in recent years. The nutritional and bioactive characterization of fruits and their byproducts, as well as their use in the formulation of new food products, is advisable, contributing to decrease the global concerns related to food waste and food security. Moreover, the compounds present in these raw materials and the study of their biological properties can promote health and help to prevent some chronic diseases. Opuntia ficus-indica (L.) Mill. (prickly pear) is a plant that grows wild in the arid and semi-arid regions of the world, being a food source for ones and a potential for others, but not properly valued. This paper carries out an exhaustive review of the scientific literature on the nutritional composition and bioactive compounds of prickly pear and its constituents, as well as its main biological activities and applications. It is a good source of dietary fiber, vitamins and bioactive compounds. Many of its natural compounds have interesting biological activities such as anti-inflammatory, hypoglycemic and antimicrobial. The antioxidant power of prickly pear makes it a good candidate as an ingredient of new food products with fascinating properties for health promotion and/or to be used as natural extracts for food, pharmaceutic or cosmetic applications. In addition, it could be a key player in food security in many arid and semi-arid regions of the world, where there are often no more plants.