Effects of bilateral discectomy and bilateral discopexy on black merino sheep rumination kinematics: TEMPOJIMS – Phase 1 – pilot blinded, randomized preclinical study

Background: The temporomandibular joint interposal study (TEMPOJIMS) is a rigorous preclinical trial divided in 2 phases. In phase 1 the authors investigated the role of the TMJ disc and in phase 2 the authors evaluated 3 different interposal materials. The present work of TEMPOJIMS - phase 1, investigated the effects of bilateral discectomy and discopexy in sheep mastication and rumination. Methods: This randomized, blinded and controlled preclinical trial (in line with the ARRIVE guidelines) was conducted in 9 Black Merino sheep to evaluate changes in mastication and rumination after bilateral discectomy and bilateral discopexy, by comparing with a sham surgery control group. The outcomes evaluated were: (1) absolute masticatory time; (2) ruminant time per cycle; (3) ruminant kinematics, and (4) ruminant area. After baseline evaluation and surgical interventions, the outcomes were recorded over 3 successive days, every 30 days, for 6 months. Results: The first month after intervention seemed to be the critical period for significant kinematic changes in the discectomy and discopexy groups. However, 6 months after the bilateral interventions, no significant changes were noticed when compared with the control group. Conclusions: In this study, bilateral discectomy and discopexy had no significant effect in mastication and ruminatory movement. The introduction of kinematic evaluation presents a new challenge that may contribute to the improvement of future studies on the TMJ domain.

Palavras-chave

Black merino sheep Discectomy Discopexy Kinematics Preclinical trial TMJ

URI

http://hdl.handle.net/10400.26/33033

Citação

Ângelo DF, Gil FM, González-García R, et al. Effects of bilateral discectomy and bilateral discopexy on black Merino sheep rumination kinematics: TEMPOJIMS - phase 1 - pilot blinded, randomized preclinical study. J Craniomaxillofac Surg. 2018;46(2):346-355. doi:10.1016/j.jcms.2017.11.022

Editora

Elsevier

DOI

10.1016/j.jcms.2017.11.022

Coleções

EM - Artigos Científicos

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