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The effect of ginger (Zingiber officinale Roscoe) aqueous extract on postprandial glycemia in nondiabetic adults : a randomized controlled trial

datacite.subject.fosCiências Médicas::Ciências da Saúde
datacite.subject.sdg03:Saúde de Qualidade
dc.contributor.authorDiakos, Alda
dc.contributor.authorSilva, Maria Leonor
dc.contributor.authorBrito, José
dc.contributor.authorMoncada, Margarida
dc.contributor.authorMesquita, Maria Fernanda de
dc.contributor.authorBernardo, Maria Alexandra
dc.date.accessioned2026-03-16T14:58:54Z
dc.date.available2026-03-16T14:58:54Z
dc.date.issued2023-03
dc.description.abstractGinger has shown beneficial effects on blood glucose control due to its antioxidant and anti-inflammatory properties. The present study investigated the effect of ginger aqueous extract on postprandial glucose levels in nondiabetic adults and characterized its antioxidant activity. Twenty-four nondiabetic participants were randomly assigned into two groups (NCT05152745), the intervention group (n = 12) and the control group (n = 12). Both groups were administered 200 mL of an oral glucose tolerance test (OGTT), after which participants in the intervention group ingested 100 mL of ginger extract (0.2 g/100 mL). Postprandial blood glucose was measured while fasting and after 30, 60, 90, and 120 min. The total phenolic content, flavonoid content, and antioxidant activity of ginger extract were quantified. In the intervention group, the incremental area under the curve for glucose levels decreased significantly (p < 0.001) and the maximum glucose concentration significantly reduced (p < 0.001). The extract possessed a polyphenolic content of 13.85 mg gallic acid equivalent/L, a flavonoid content of 3.35 mg quercetin equivalent/L, and a high superoxide radical inhibitory capacity (45.73%). This study showed that ginger has a beneficial effect on glucose homeostasis under acute conditions and encourages the use of ginger extract as a promising source of natural antioxidants.eng
dc.identifier.citationDiakos A, Silva ML, Brito J, Moncada M, de Mesquita MF, Bernardo MA. The Effect of Ginger (Zingiber officinale Roscoe) Aqueous Extract on Postprandial Glycemia in Nondiabetic Adults: A Randomized Controlled Trial. Foods. 2023; 12(5):1037. https://doi.org/10.3390/foods12051037
dc.identifier.doi10.3390/foods12051037
dc.identifier.issn2304-8158
dc.identifier.urihttp://hdl.handle.net/10400.26/62205
dc.language.isoeng
dc.peerreviewedyes
dc.publisherMDPI
dc.relation.hasversionhttps://doi.org/10.3390/foods12051037
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectginger
dc.subjectZingibre officinalle Roscoe
dc.subjectpostprandial glycemia
dc.subjectantioxidant
dc.subjectpolyphenols
dc.subjectflavonoids
dc.titleThe effect of ginger (Zingiber officinale Roscoe) aqueous extract on postprandial glycemia in nondiabetic adults : a randomized controlled trialeng
dc.typecontribution to journal
dspace.entity.typePublication
oaire.citation.issue5
oaire.citation.startPage1037
oaire.citation.titleFoods
oaire.citation.volume12
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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