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Publication
Etiologia e tratamento das infeções endodônticas
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 5.67 MB | Adobe PDF |
Authors
Advisor(s)
Abstract(s)
As infeções endodônticas são causadoras de elevada morbilidade e quando não
adequadamente tratadas podem causar infeções sistémicas muito graves. Para melhor
conhecer e tratar adequadamente estas infeções é importante saber quais os
microrganismos que as causam mais frequentemente e qual a resposta destes
microrganismos ao tratamento com antibióticos e antissépticos aplicados localmente.
Contudo, a informação existente atualmente sobre a etiologia e tratamento das infeções
endodônticas é bastante confusa e dispersa devido à pletora de microrganismos que
podem causar estas infeções, à utilização de diferentes métodos para a identificação
desses microrganismos e às múltiplas estratégias de tratamento disponíveis. Neste
contexto, os objectivos deste trabalho serão caracterizar o estado da arte sobre o
microbioma das infeções endodônticas agudas, crónicas e recidivantes à luz de métodos
de sequencição genómica de última geração, e caracterizar o estado da arte sobre o
tratamento das infeções endodônticas com irrigantes e antibióticos.
Endodontic infections cause high morbidity and when not properly treated can cause very serious systemic infections. To better understand and treat these infections adequately, it is important to know which microorganisms cause them most frequently and what is the response of these microorganisms to treatment with locally applied antibiotics and antiseptics. However, the current information on the etiology and treatment of endodontic infections is very confusing and dispersed due to the plethora of microorganisms that can cause these infections, the use of different methods to identify these microorganisms and the multiple treatment strategies available. In this context, the objectives of this work will be to characterize the state of the art on the microbiome of acute, chronic and recurrent endodontic infections in the light of the latest genomic sequencing methods and to characterize the state of the art on the treatment of endodontic infections with irrigators and antibiotics.
Endodontic infections cause high morbidity and when not properly treated can cause very serious systemic infections. To better understand and treat these infections adequately, it is important to know which microorganisms cause them most frequently and what is the response of these microorganisms to treatment with locally applied antibiotics and antiseptics. However, the current information on the etiology and treatment of endodontic infections is very confusing and dispersed due to the plethora of microorganisms that can cause these infections, the use of different methods to identify these microorganisms and the multiple treatment strategies available. In this context, the objectives of this work will be to characterize the state of the art on the microbiome of acute, chronic and recurrent endodontic infections in the light of the latest genomic sequencing methods and to characterize the state of the art on the treatment of endodontic infections with irrigators and antibiotics.
Description
Dissertação para obtenção do grau de Mestre no Instituto Universitário Egas Moniz
Keywords
Infeção endodôntica Microbiota endopatogénica Tratamento das infeções endodônticas Soluções irrigantes