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Bioanalytical approach-ageing, exercise and oxidative stress

2020-05-27Journal article Open access
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dc.contributor.authorValado, Ana
dc.contributor.authorLopes, Diana
dc.contributor.authorOsório, Nádia
dc.contributor.authorCaseiro, Armando
dc.contributor.authorFigueiredo, João
dc.contributor.authorPatrício, Cristina
dc.contributor.authorPacheco, Maria Paula
dc.contributor.authorOostingh, Gertie Janneke
dc.contributor.authorGabriel, António José dos Santos
dc.date.accessioned2021-03-05T20:54:15Z
dc.date.available2021-03-05T20:54:15Z
dc.date.issued2020-05-27
dc.description.abstractAbstract: Exercise interferes with the ageing, causing changes in markers of the antioxidant system, such as nitric oxide (NO) and uric acid. Aim: The objective of this study was to evaluate if regular exercise affects the ageing process by causing changes in the antioxidant markers, nitric oxide and uric acid, in individuals aged ≥ 65 years, subjected to an exercise plan. Methods: The study involved 12 participants distributed in an experimental and control group. The experimental group performed exercises guided by a physiotherapist during 12 weeks. Three blood samples were collected from participants: T0, at the start of the study; T1, after 12 weeks of exercise and T2, 12 weeks after finishing the exercise. NO and uric acid were quantified with commercial kits. The statistics were performed using SPSS and the ANOVA and Student t-tests were applied. Result: In the experimental group, the mean values of NO showed an increase between T0 and T1, with a slight decrease between T1 and T2. Similar effects were observed for the uric acid concentration in the experimental group, with statistical significance from T0 to T1. Conclusion: After exercise, there was an increase in blood uric acid and NO levels, highlighting the importance of moderate and controlled exercise practice. Therefore, exercise seems relevant and beneficial in activating antioxidant mechanisms.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.19080/JCMAH.2020.11.555810pt_PT
dc.identifier.issn2572-1232
dc.identifier.urihttp://hdl.handle.net/10400.26/35835
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherJuniper publisherspt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/pt_PT
dc.subjectAgeingpt_PT
dc.subjectExercisept_PT
dc.subjectNitric oxidept_PT
dc.subjectUric acidpt_PT
dc.subjectAgeing processpt_PT
dc.subjectSignalling pathwaypt_PT
dc.subjectPostponementpt_PT
dc.subjectBiological processpt_PT
dc.subjectEnvelhecimentopt_PT
dc.subjectExercício físicopt_PT
dc.subjectÓxido nítricopt_PT
dc.subjectÁcido úricopt_PT
dc.subjectProcessos biológicospt_PT
dc.titleBioanalytical approach-ageing, exercise and oxidative stresspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage49pt_PT
oaire.citation.issue2pt_PT
oaire.citation.startPage45pt_PT
oaire.citation.titleJournal of Complementary Medicine and Alternative Healthcarept_PT
oaire.citation.volume11pt_PT
person.familyNameValado
person.familyNameOsório
person.familyNameCaseiro
person.familyNameFigueiredo
person.familyNameOostingh
person.familyNamedos Santos Gabriel
person.givenNameAna Maria
person.givenNameNádia
person.givenNameArmando
person.givenNameJoão
person.givenNameGertie Janneke
person.givenNameAntónio José
person.identifier.ciencia-idF217-BA65-C0D2
person.identifier.ciencia-id271E-2D9B-E7F3
person.identifier.ciencia-id4012-A0D8-66D6
person.identifier.ciencia-idF41B-EC2F-917F
person.identifier.ciencia-idE819-F5B0-626C
person.identifier.orcid0000-0002-0157-6648
person.identifier.orcid0000-0001-9559-2165
person.identifier.orcid0000-0001-7844-0506
person.identifier.orcid0000-0002-9829-1592
person.identifier.orcid0000-0001-5083-217X
person.identifier.ridL-8385-2013
person.identifier.ridJOZ-8716-2023
person.identifier.scopus-author-id57188973499
person.identifier.scopus-author-id35738464000
person.identifier.scopus-author-id56321727300
person.identifier.scopus-author-id6507748784
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
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