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IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper

2020-02Journal article Open access
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dc.contributor.authorAnsotegui, IJ
dc.contributor.authorMelioli, G
dc.contributor.authorCanonica, GW
dc.contributor.authorCaraballo, L
dc.contributor.authorVilla, E
dc.contributor.authorEbisawa, M
dc.contributor.authorPassalacqua, G
dc.contributor.authorSavi, E
dc.contributor.authorEbo, DJ
dc.contributor.authorGómez, RM
dc.contributor.authorLuengo Sánchez, O
dc.contributor.authorOppenheimer, JJ
dc.contributor.authorJensen-Jarolim, E
dc.contributor.authorFischer, DA
dc.contributor.authorHaahtela, T
dc.contributor.authorAntila, M
dc.contributor.authorBousquet, JJ
dc.contributor.authorCardona, V
dc.contributor.authorChiang, WC
dc.contributor.authorDemoly, PM
dc.contributor.authorDuBuske, LM
dc.contributor.authorFerrer Puga, M
dc.contributor.authorGerth van Wijk, R
dc.contributor.authorGonzález Díaz, SN
dc.contributor.authorGonzalez-Estrada, A
dc.contributor.authorJares, E
dc.contributor.authorKalpaklioğlu, AF
dc.contributor.authorKase Tanno, L
dc.contributor.authorKowalski, ML
dc.contributor.authorLedford, DK
dc.contributor.authorMonge Ortega, OP
dc.contributor.authorMorais Almeida, M
dc.contributor.authorPfaar, O
dc.contributor.authorPoulsen, LK
dc.contributor.authorPawankar, R
dc.contributor.authorRenz, HE
dc.contributor.authorRomano, AG
dc.contributor.authorRosário Filho, NA
dc.contributor.authorRosenwasser, L
dc.contributor.authorSánchez Borges, MA
dc.contributor.authorScala, E
dc.contributor.authorSenna, GE
dc.contributor.authorSisul, JC
dc.contributor.authorTang, MK
dc.contributor.authorThong, By
dc.contributor.authorValenta, R
dc.contributor.authorWood, RA
dc.contributor.authorZuberbier, T
dc.date.accessioned2020-04-16T20:24:09Z
dc.date.available2020-04-16T20:24:09Z
dc.date.issued2020-02
dc.description.abstractCurrently, testing for immunoglobulin E (IgE) sensitization is the cornerstone of diagnostic evaluation in suspected allergic conditions. This review provides a thorough and updated critical appraisal of the most frequently used diagnostic tests, both in vivo and in vitro. It discusses skin tests, challenges, and serological and cellular in vitro tests, and provides an overview of indications, advantages and disadvantages of each in conditions such as respiratory, food, venom, drug, and occupational allergy. Skin prick testing remains the first line approach in most instances; the added value of serum specific IgE to whole allergen extracts or components, as well as the role of basophil activation tests, is evaluated. Unproven, non-validated, diagnostic tests are also discussed. Throughout the review, the reader must bear in mind the relevance of differentiating between sensitization and allergy; the latter entails not only allergic sensitization, but also clinically relevant symptoms triggered by the culprit allergen.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationWorld Allergy Organ J. 2020 Feb 25;13(2):100080.pt_PT
dc.identifier.doi10.1016/j.waojou.2019.100080pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/32012
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectHipersensibilidade/diagnósticopt_PT
dc.subjectTestes Sorológicospt_PT
dc.subjectImunoglobulina Ept_PT
dc.subjectTestes Cutâneospt_PT
dc.subjectSerologic Testspt_PT
dc.subjectHypersensitivity/diagnosispt_PT
dc.subjectImmunoglobulin Ept_PT
dc.subjectSkin Testspt_PT
dc.titleIgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paperpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue2pt_PT
oaire.citation.startPage100080pt_PT
oaire.citation.titleThe World Allergy Organization journalpt_PT
oaire.citation.volume13pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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