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Age-related expression of TGF beta family receptors in human cumulus oophorus cells

2017Journal article Open access
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dc.contributor.authorRibeiro, A.
dc.contributor.authorFreitas, C.
dc.contributor.authorMatos, L.
dc.contributor.authorGouveia, A.
dc.contributor.authorGomes, F.
dc.contributor.authorSilva Carvalho, J. L.
dc.contributor.authorAlmeida, H.
dc.date.accessioned2020-07-28T10:15:02Z
dc.date.available2020-07-28T10:15:02Z
dc.date.issued2017
dc.description.abstractDuring ovarian follicle growth, local cellular interactions are essential for oocyte quality acquisition and successful fertilization. While cumulus cells (CCs) nurture oocytes, they also deliver oocyte-secreted factors (OSFs) that activate receptors on CCs. We hypothesized that disturbance of those interactions contributes to age-related lower reproductive success in women submitted to assisted reproductive technology treatments.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRibeiro, A., Freitas, C., Matos, L. et al. Age-related expression f TGF beta family receptors in human cumulus oophorus cells. J Assist Reprod Genet 34, 1121–1129 (2017).pt_PT
dc.identifier.doi10.1007/s10815-017-0930-6pt_PT
dc.identifier.issn1058-0468 (Print) 1573-7330 (Online)
dc.identifier.urihttp://hdl.handle.net/10400.26/33005
dc.language.isoengpt_PT
dc.publisherSpringerpt_PT
dc.subjectAdultpt_PT
dc.subjectAnaplastic Lymphoma Kinasept_PT
dc.subjectBone Morphogenetic Protein Receptors, Type Ipt_PT
dc.subjectBone Morphogenetic Protein Receptors, Type IIpt_PT
dc.subjectCumulus Cellspt_PT
dc.subjectFemalept_PT
dc.subjectFertilization in Vitropt_PT
dc.subjectGene Expression Regulation, Developmentalpt_PT
dc.subjectHumanspt_PT
dc.subjectMiddle Agedpt_PT
dc.subjectOocytespt_PT
dc.subjectOvarian Folliclept_PT
dc.subjectProtein-Serine-Threonine Kinasespt_PT
dc.subjectReceptor Protein-Tyrosine Kinasespt_PT
dc.subjectReceptor, Transforming Growth Factor-beta Type Ipt_PT
dc.subjectReceptors, Transforming Growth Factor betapt_PT
dc.subjectReproductive Techniques, Assistedpt_PT
dc.subjectPortugalpt_PT
dc.titleAge-related expression of TGF beta family receptors in human cumulus oophorus cellspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1129pt_PT
oaire.citation.issue9pt_PT
oaire.citation.startPage1121pt_PT
oaire.citation.titleJournal of Assisted Reproduction and Geneticspt_PT
oaire.citation.volume34pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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