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Publication
Linfoma canino: novas abordagens terapêuticas
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Advisor(s)
Abstract(s)
O linfoma é uma doença de elevada incidência na população canina, sendo um dos
tumores hematopoiéticos mais frequentes nesta espécie.
Sendo um dos tipos de tumores com maior resposta à quimioterapia, esta é
actualmente a terapia de eleição alcançando, quando devidamente empregue e monitorizada,
um aumento significativo na duração e qualidade de vida do paciente. Com o constante estudo
e compreensão do comportamento deste tipo de tumor têm surgido nos últimos anos novas
abordagens terapêuticas como a imunoterapia, radioterapia e o transplante de medula óssea.
Estas novas terapêuticas são usadas de forma coadjuvante à terapêutica quimioterápica e têm
como objectivo melhorar as respostas e aumentar a sobrevivência dos pacientes, com uma
diminuição dos efeitos secundários.
É assim objectivo desta dissertação fazer uma revisão da literatura actual sobre as
novas linhas terapêuticas do linfoma canino em medicina veterinária, fazendo previamente uma
breve revisão sobre a classificação, apresentação clínica, diagnóstico e tratamento
quimioterápico do linfoma canino.
Lymphoma is a highly incident disease in the canine population, being one the most frequent hematopoietic tumour in this species. Being highly responsive to chemotherapy this is the current treatment of choice, and when correctly used and monitored, a significant increase in length and quality of life is observed. With the continuous study and understanding of the behaviour of this kind of tumour, new therapies have arised, such as Immunotherapy, radiotherapy and bone marrow transplantation. These new therapheutic strategies are used in conjunction with chemotherapy and aim to improve the therapeutic response and increasing survival time of patients, with a decrease in the adverse effects. Therefore, it is the aim of this paper to review all the new therapeutic strategies employed in Veterinary Medicine, along with a brief description of the classification, clinical presentation, diagnosis and chemotherapy treatment of canine lymphoma.
Lymphoma is a highly incident disease in the canine population, being one the most frequent hematopoietic tumour in this species. Being highly responsive to chemotherapy this is the current treatment of choice, and when correctly used and monitored, a significant increase in length and quality of life is observed. With the continuous study and understanding of the behaviour of this kind of tumour, new therapies have arised, such as Immunotherapy, radiotherapy and bone marrow transplantation. These new therapheutic strategies are used in conjunction with chemotherapy and aim to improve the therapeutic response and increasing survival time of patients, with a decrease in the adverse effects. Therefore, it is the aim of this paper to review all the new therapeutic strategies employed in Veterinary Medicine, along with a brief description of the classification, clinical presentation, diagnosis and chemotherapy treatment of canine lymphoma.
Description
Keywords
Linfoma canino Quimioterapia Imunoterapia Imunologia tumural Terapias "convencionais" Terapias "inovadoras" Radioterapia Transplante de medula Canine limphoma Chemotherapy Immunotherapy Cancer immunology Conventional therapies New therapies Radiotherapy Bone marrow trasplantation