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Serum Zn levels in dysphagic patients who underwent endoscopic gastrostomy for long term enteral nutrition

dc.contributor.authorSantos, Carla Adriana
dc.contributor.authorFonseca, Jorge
dc.contributor.authorBrito, José
dc.contributor.authorFernandes, Tânia
dc.contributor.authorGonçalves, Luísa
dc.contributor.authorGuerreiro, António Sousa
dc.date.accessioned2017-08-03T13:08:58Z
dc.date.available2017-08-03T13:08:58Z
dc.date.issued2014-02
dc.description.abstract"Background and aims: Dysphagic patients who underwent endoscopic gastrostomy (PEG) usually present protein-energy malnutrition, but little is known about micronutrient malnutrition. The aim of the present study was the evaluation of serum zinc in patients who underwent endoscopic gastrostomy and its relationship with serum proteins, whole blood zinc, and the nature of underlying disorder. Methods: From patients that underwent gastrostomy a blood sample was obtained minutes before the procedure. Serum and whole blood zinc was evaluated using Wavelength Dispersive X-ray Fluorescence Spectroscopy. Serum albumin and transferrin were evaluated. Patients were studied as a whole and divided into two groups: head and neck cancer (HNC) and neurological dysphagia (ND). Results: The study involved 32 patients (22 males), aged 43-88 years: HNC = 15, ND = 17. Most (30/32) had low serum zinc, 17/32 presented normal values of whole blood zinc. Only two, with traumatic brain injury, presented normal serum zinc. Serum zinc levels showed no differences between HNC and ND patients. There was no association between serum zinc and serum albumin or transferrin. There was no association between serum and whole blood zinc. Conclusions: Patients had low serum zinc when gastrostomy was performed, similar in HNC and ND, being related with prolonged fasting and unrelated with the underlying disease. Decrease serum zinc was unrelated with low serum proteins. Serum zinc was more sensitive than whole blood zinc for identifying reduced zinc intake. Teams taking care of PEG-patients should include zinc evaluation as part of the nutritional assessment, or include systematic dietary zinc supply."pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationADRIANA SANTOS, Carla et al. Serum Zn levels in dysphagic patients who underwent endoscopic gastrostomy for long term enteral nutrition. Nutr. Hosp. [online]. 2014, vol.29, n.2, pp.359-364. ISSN 1699-5198. http://dx.doi.org/10.3305/nh.2014.29.2.7035.pt_PT
dc.identifier.doi10.3305/nh.2014.29.2.7035pt_PT
dc.identifier.issn1699-5198
dc.identifier.urihttp://hdl.handle.net/10400.26/18736
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherGrupo Aránpt_PT
dc.relation.publisherversionhttp://scielo.isciii.es/scielo.php?pid=0212-1611&script=sci_serialpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/pt_PT
dc.subjectZincpt_PT
dc.subjectGastrostomypt_PT
dc.subjectPEGpt_PT
dc.subjectDysphagiapt_PT
dc.subjectMalnutritionpt_PT
dc.titleSerum Zn levels in dysphagic patients who underwent endoscopic gastrostomy for long term enteral nutritionpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage364pt_PT
oaire.citation.startPage359pt_PT
oaire.citation.titleNutricion Hospitalariapt_PT
oaire.citation.volume29(2)pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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