Chromatographic approaches in forensic toxicological analysis

Barroso, Mário

Publication

Chromatographic approaches in forensic toxicological analysis

2023Lecture

dc.contributor.author	Barroso, Mário
dc.date.accessioned	2024-01-24T09:27:28Z
dc.date.available	2024-01-24T09:27:28Z
dc.date.issued	2023
dc.description	Conferência por convite no 13º Encontro Nacional de Cromatografia, que decorreu em Dezembro de 2023 em Lisboa	pt_PT
dc.description.abstract	Chromatography plays a fundamental role in forensic toxicology, serving as a powerful analytical tool for identifying and quantifying toxic substances in biological samples. Indeed, it is the science of separation, and it is used to isolate components from complex mixtures. Gas and liquid chromatography instruments coupled with mass spectrometry equip forensic laboratories nowadays, and enable accurately identifying and quantifying drugs and metabolites in several biological specimens, from the most common blood and urine to the unconventional oral fluid and hair samples. These techniques allow the efficient separation of the compounds of interest from endogenous interferences (e.g. proteins, lipids) and their detection. For most substances of toxicological interest, this detection is performed by mass spectrometry, as only this highly selective and sensitive technology is capable of unequivocally identifying the substances present in a sample, allowing obtaining forensically valid and sound results. In this talk, practical routine cases will be presented and discussed.	pt_PT
dc.description.version	info:eu-repo/semantics/draft	pt_PT
dc.identifier.uri	http://hdl.handle.net/10400.26/49289
dc.language.iso	por	pt_PT
dc.peerreviewed	no	pt_PT
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	pt_PT
dc.subject	Cromatografia	pt_PT
dc.subject	Toxicologia Forense	pt_PT
dc.subject	Chromatography	pt_PT
dc.subject	Forensic Toxicology	pt_PT
dc.title	Chromatographic approaches in forensic toxicological analysis	pt_PT
dc.type	lecture
dspace.entity.type	Publication
oaire.citation.conferencePlace	Lisboa	pt_PT
oaire.citation.title	13º Encontro Nacional de Cromatografia	pt_PT
person.familyName	Barroso
person.givenName	Mário
person.identifier.ciencia-id	5110-F476-ECCC
person.identifier.orcid	0000-0001-8848-2734
person.identifier.scopus-author-id	35329243100
rcaap.rights	openAccess	pt_PT
rcaap.type	lecture	pt_PT
relation.isAuthorOfPublication	294b555e-48c4-4013-b981-b8917400c56c
relation.isAuthorOfPublication.latestForDiscovery	294b555e-48c4-4013-b981-b8917400c56c